Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Mansoor Amiji"'
Publikováno v:
Bioactive Materials, Vol 22, Iss , Pp 551-566 (2023)
Cancer therapy is undergoing a paradigm shift toward immunotherapy focusing on various approaches to activate the host immune system. As research to identify appropriate immune cells and activate anti-tumor immunity continues to expand, scientists ar
Externí odkaz:
https://doaj.org/article/934e592e4d2f442c85b6e0bdf573db83
Autor:
Christopher Francis, Mansoor Amiji
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 30, Iss , Pp 64-65 (2022)
The field of gene editing continues to expand significantly and is entering a time of unprecedented utility. Academia and industry look to conquer genetic-based disease with viral and non-viral-delivered CRISPR-Cas9. The most widely used Cas9 protein
Externí odkaz:
https://doaj.org/article/60718ddfda4c4709a4fca460f86fa602
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Abstract Therapies targeting epigenetic changes for cancer treatment are in Phase I/II trials; however, all of these target only nuclear DNA. Emerging evidence suggests presence of methylation marks on mitochondrial DNA (mtDNA); but their contributio
Externí odkaz:
https://doaj.org/article/f6288c51414948cfa657e839016a80ed
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24075 (2011)
The treatment of multi-drug resistant (MDR) cancer is a clinical challenge. Many MDR cells over-express epidermal growth factor receptor (EGFR). We exploit this expression through the development of EGFR-targeted, polymer blend nanocarriers for the t
Externí odkaz:
https://doaj.org/article/a13eef515d4547849c173f3c16a164b3
Publikováno v:
Expert Opinion on Drug Delivery. 20:489-506
Publikováno v:
Nucleic Acid Therapeutics. 33:35-44
Autor:
Sevde Altuntas, Harkiranpreet Kaur Dhaliwal, Ahmed Eid Radwan, Mansoor Amiji, Fatih Buyukserin
Publikováno v:
Biomaterials Science. 11:181-194
Epidermal growth factor (EGF) is required for various regulations of skin tissue including wound healing; however, it has limited stability due to the physicochemical conditions of the wound milieu. The lack of functional EGF within the wound can cau
Publikováno v:
Journal of Controlled Release. 345:721-733
Current methods of STING activation based on intra-tumoral injections of cyclic dinucleotides (CDNs) are not suitable for addressing tumor heterogeneity or for inaccessible, metastatic and abscopal tumors. In this study, we developed systemically adm
Publikováno v:
Nucleic acid therapeutics.
Despite wide recognition as a disease of pandemic proportions, effective treatments for nonalcoholic fatty liver disease (NAFLD) remain elusive. Most of the current clinical programs aim to reduce hepatic fat accumulation and, thus, prevent downstrea
Publikováno v:
Bioactive materials. 22
Cancer therapy is undergoing a paradigm shift toward immunotherapy focusing on various approaches to activate the host immune system. As research to identify appropriate immune cells and activate anti-tumor immunity continues to expand, scientists ar