Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Mansi Prakash"'
Autor:
Mansi Prakash, Jeremy Murphy, Robyn St Laurent, Nina Friedman, Emmanuel L. Crespo, Andreas Bjorefeldt, Akash Pal, Yuvraj Bhagat, Julie A. Kauer, Nathan C. Shaner, Diane Lipscombe, Christopher I. Moore, Ute Hochgeschwender
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Prakash et al. develop an approach to control synaptically connected elements using bioluminescent light, in which Luciferase-generated light, originating from a presynaptic axon terminal, modulates an opsin in its postsynaptic target to form an ‘o
Externí odkaz:
https://doaj.org/article/466740bf581a4a9e9e4cf7688016fe99
Autor:
Eric D. Petersen, Erik D. Sharkey, Akash Pal, Lateef O. Shafau, Jessica Zenchak-Petersen, Alex J. Peña, Anu Aggarwal, Mansi Prakash, Ute Hochgeschwender
Publikováno v:
Frontiers in Neurology, Vol 12 (2022)
The ability to manipulate specific neuronal populations of the spinal cord following spinal cord injury (SCI) could prove highly beneficial for rehabilitation in patients through maintaining and strengthening still existing neuronal connections and/o
Externí odkaz:
https://doaj.org/article/c6ec47f021a347ae8a0141fc29f29613
Autor:
Emmanuel L. Crespo, Mansi Prakash, Andreas Bjorefeldt, William E. Medendorp, Nathan C. Shaner, Diane Lipscombe, Christopher I. Moore, Ute Hochgeschwender
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100667- (2021)
Summary: Bioluminescent optogenetics (BL-OG) allows activation of photosensory proteins, such as opsins, by either fiberoptics or by administering a luciferin. BL-OG thus confers both optogenetic and chemogenetic access within the same genetically ta
Externí odkaz:
https://doaj.org/article/3c21176793034b0dae2223b29eebc3f3
Autor:
Ebenezer C. Ikefuama, Griffin E. Kendziorski, Kevin Anderson, Lateef Shafau, Mansi Prakash, Ute Hochgeschwender, Eric D. Petersen
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 12994 (2022)
Irrespective of the many strategies focused on dealing with spinal cord injury (SCI), there is still no way to restore motor function efficiently or an adequate regenerative therapy. One promising method that could potentially prove highly beneficial
Externí odkaz:
https://doaj.org/article/c152378dad224d60b702492d347b367c
Autor:
William E. Medendorp, Andreas Bjorefeldt, Emmanuel L. Crespo, Mansi Prakash, Akash Pal, Madison L. Waddell, Christopher I. Moore, Ute Hochgeschwender
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102157- (2021)
Summary: In genetic and pharmacological models of neurodevelopmental disorders, and human data, neural activity is altered within the developing neocortical network. This commonality begs the question of whether early enhancement in excitation might
Externí odkaz:
https://doaj.org/article/2fac34280f43468297b5619b71767bfc
Autor:
Sonia Franco, Stephen Desiderio, David L. Huso, Tameca Jefferson, Mansi Prakash, Jeremy Chou, Taylor L. Reynolds, Ivana Rybanska-Spaeder
PDF file - 7618K, S1. Analysis of the genetic interaction between 53BP1 and ATM in organismal growth and development. S2. Analysis of ploidy in Trp53bp1-/-/Atm-/- lymphomas. S3. Analysis of Trp53bp1-/-/Atm-/- thymic lymphomas by TCRα/δ locus FISH.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31767e5ab37baddd45741c9e34e6f321
https://doi.org/10.1158/1541-7786.22510146.v1
https://doi.org/10.1158/1541-7786.22510146.v1
Autor:
Sonia Franco, Stephen Desiderio, David L. Huso, Tameca Jefferson, Mansi Prakash, Jeremy Chou, Taylor L. Reynolds, Ivana Rybanska-Spaeder
The DNA damage response (DDR) factors ataxia telangiectasia mutated (ATM) and p53 binding protein 1 (53BP1) function as tumor suppressors in humans and mice, but the significance of their mutual interaction to the suppression of oncogenic translocati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::909f6f3dc37c7ac20e644f7ac4b433c1
https://doi.org/10.1158/1541-7786.c.6539526
https://doi.org/10.1158/1541-7786.c.6539526
Autor:
Nathan C. Shaner, Ute Hochgeschwender, Mansi Prakash, Julie A. Kauer, Emmanual Crespo, Andreas Bjorefeldt, Akash Pal, Nina Friedman, Diane Lipscombe, Robyn St Laurent, Jeremy W. Murphy, Yuvraj Bhagat, Christopher I. Moore
Publikováno v:
Communications Biology
Communications biology, vol 5, iss 1
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Communications biology, vol 5, iss 1
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Understanding percepts, engrams and actions requires methods for selectively modulating synaptic communication between specific subsets of interconnected cells. Here, we develop an approach to control synaptically connected elements using bioluminesc
Publikováno v:
Journal of visualized experiments : JoVE. (174)
Bioluminescence - light emitted by a luciferase enzyme oxidizing a small molecule substrate, a luciferin - has been used in vitro and in vivo to activate light-gated ion channels and pumps in neurons. While this bioluminescent optogenetics (BL-OG) ap
Publikováno v:
Journal of Visualized Experiments.
Bioluminescence - light emitted by a luciferase enzyme oxidizing a small molecule substrate, a luciferin - has been used in vitro and in vivo to activate light-gated ion channels and pumps in neurons. While this bioluminescent optogenetics (BL-OG) ap