Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mansi Narula"'
Autor:
Yael Gernez, Mansi Narula, Alma-Martina Cepika, Juanita Valdes Camacho, Elisabeth G. Hoyte, Kirsten Mouradian, Bertil Glader, Deepika Singh, Bindu Sathi, Latha Rao, Ana L. Tolin, Kenneth I. Weinberg, David B. Lewis, Rosa Bacchetta, Katja G. Weinacht
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Biallelic mutations in the ACP5 gene cause spondyloenchondrodysplasia with immune dysregulation (SPENCDI). SPENCDI is characterized by the phenotypic triad of skeletal dysplasia, innate and adaptive immune dysfunction, and variable neurologic finding
Externí odkaz:
https://doaj.org/article/3352cc1afba34f049e385d6523a3af06
Autor:
Spyridoula Vasileiou, Manik Kuvalekar, Yovana Velazquez, Ayumi Watanabe, Mansi Narula, Aster G. Workineh, Matthew French-Kim, Alejandro Torres Chavez, Sarah Gilmore, Cliona M. Rooney, Ann M. Leen
Publikováno v:
Haematologica, Vol 108, Iss 7 (2022)
Externí odkaz:
https://doaj.org/article/6cfcb57140cf4ef5bab7606016e44333
Autor:
Mark M Davis, Alice Bertaina, Alma-Martina Cepika, Pauline P Chen, Molly Uyeda, Brandon Cieniewicz, Mansi Narula, Laura Amaya, David M Louis, Liwen Xu, Xuhuai Ji, Rajni Agarwal-Hashmi, Everett Meyer, Rosa Bacchetta, Maria Grazia Roncarolo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/f9799575cfe141379cda2fae237c1005
Autor:
Šimon Borna, Esmond Lee, Uma Lakshmanan, Melissa Mavers, Mansi Narula, Akshaya Ramachandran, Jeanette Baker, Janika Schulze, Sven Olek, Louis Marois, Yael Gernez, Monica Bhatia, Alice Bertaina, Maria Grazia Roncarolo, Eric Meffre, Rosa Bacchetta
The monogenic autoimmune disease Immunedysregulation polyendocrynopathy entheropathy X-linked syndrome (IPEX) has elucidated the essential function of the transcription factor FOXP3 and of thymic-derived regulatory T (Treg) cells in controlling autoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0519159d5ff8a9bc293382f3e0e0aea
https://doi.org/10.1101/2022.07.10.499494
https://doi.org/10.1101/2022.07.10.499494
Autor:
Mansi Narula, Uma Lakshmanan, Simon Borna, Janika J. Schulze, Tyson H. Holmes, Nicholas Harre, Matthew Kirkey, Akshaya Ramachandran, Veronica Maria Tagi, Federica Barzaghi, Eyal Grunebaum, Julia E.M. Upton, Vy Hong-Diep Kim, Christian Wysocki, Victoria R. Dimitriades, Kenneth Weinberg, Katja G. Weinacht, Yael Gernez, Bindu K. Sathi, Magdalena Schelotto, Matthew Johnson, Sven Olek, Christoph Sachsenmaier, Maria-Grazia Roncarolo, Rosa Bacchetta
Publikováno v:
The Journal of allergy and clinical immunology. 151(1)
Forkhead box protein 3 (FOXP3) is the master transcription factor in CD4We sought to study the type and extent of immunologic abnormalities that remain ill-defined in IPEX, across genetic and clinical heterogeneity.We performed Treg-cell-specific epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b89fbdb16a8dec9dc59ba6458a6fdaa6
https://pubmed.ncbi.nlm.nih.gov/36152823
https://pubmed.ncbi.nlm.nih.gov/36152823
Autor:
Alice Bertaina, Laura Amaya, Maria Grazia Roncarolo, Alma-Martina Cepika, Rajni Agarwal-Hashmi, Mark M. Davis, David M. Louis, Rosa Bacchetta, Mansi Narula, Everett Meyer, Molly Javier Uyeda, Liwen Xu, Pauline P. Chen, Brandon Cieniewicz, Xuhuai Ji
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Graft-vs-host-disease (GvHD) is a life-threatening complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT), limiting the use of this potentially curative treatment for hematological malignancies. To address this, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212e053736e83c17e18816d788c12699
https://doi.org/10.1136/jitc-2020-sitc2020.0146
https://doi.org/10.1136/jitc-2020-sitc2020.0146
Autor:
Spyridoula Vasileiou, Manik Kuvalekar, Yovana Velazquez, Ayumi Watanabe, Mansi Narula, Aster G. Workineh, Matthew French-Kim, Alejandro Torres Chavez, Sarah Gilmore, Cliona M. Rooney, Ann M. Leen
Publikováno v:
Haematologica.
Not available.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd614151faa6f2550a70f72fec376057
https://pubmed.ncbi.nlm.nih.gov/36373251
https://pubmed.ncbi.nlm.nih.gov/36373251
Autor:
Ciaran M. Lee, Gang Bao, C. S. Bauer, M. Garcia-Lloret, Ayal Hendel, Adam Sheikali, Rosa Bacchetta, Ami J. Shah, Federica Barzaghi, Alice Bertaina, S. Shipp, Maria Grazia Roncarolo, L. Froessl, Mara Pavel-Dinu, Matt Porteus, U. Lakshmanan, Mansi Narula, Esmond Lee, Holly K. Miller, Manish J. Butte, Marianne Goodwin, Laura Passerini
Publikováno v:
Science advances, vol 6, iss 19
Science Advances
Science Advances
Gene editing of FOXP3 ensures regulated expression and restored function in T cells, supporting clinical applicability.
The prototypical genetic autoimmune disease is immune dysregulation polyendocrinopathy enteropathy X-linked (IPEX) syndrome,
The prototypical genetic autoimmune disease is immune dysregulation polyendocrinopathy enteropathy X-linked (IPEX) syndrome,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aba5971fe26bda15f359faefd78db95
https://doi.org/10.1126/sciadv.aaz0571
https://doi.org/10.1126/sciadv.aaz0571
Tumor necrosis factor receptor (TNFR)-associated factor 6 (TRAF6) is an important adaptor molecule that mediates the TNFR family and interleukin-1 (IL-1)/Toll-like receptor (TLR) signaling cascades. These pathways are important for the host to contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::060404489b9d48642dacc7f13a7b0cd1
https://europepmc.org/articles/PMC5110169/
https://europepmc.org/articles/PMC5110169/