Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mansi K. Aparnathi"'
Autor:
Sami Ul Haq, Sabine Schmid, Mansi K. Aparnathi, Katrina Hueniken, Luna Jia Zhan, Danielle Sacdalan, Janice J.N. Li, Nicholas Meti, Devalben Patel, Dangxiao Cheng, Vivek Philip, Ming S. Tsao, Michael Cabanero, Daniel de Carvalho, Geoffrey Liu, Scott V. Bratman, Benjamin H. Lok
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105487- (2022)
Summary: Small-cell lung cancer (SCLC) methylome is understudied. Here, we comprehensively profile SCLC using cell-free methylated DNA immunoprecipitation followed by sequencing (cfMeDIP-seq). Cell-free DNA (cfDNA) from plasma of 74 patients with SCL
Externí odkaz:
https://doaj.org/article/0bd1264da87846d4b7d0eed1a930952d
Autor:
Benjamin H. Lok, Geoffrey Liu, Ming S. Tsao, Aaron D. Schimmer, Rod Bremner, Joel D. Pearson, Samir H. Barghout, Vijithan Sugumar, Ranya Barayan, Jessica Weiss, Lifang Song, Fariha Rahman, Vidhyasagar Venkatasubramanian, Kevin C.J. Nixon, Mansi K. Aparnathi, Safa Majeed
Supplementary Data from Targeting the Ubiquitin–Proteasome System Using the UBA1 Inhibitor TAK-243 is a Potential Therapeutic Strategy for Small-Cell Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07dec1598a9f1c977852b1ad0084664a
https://doi.org/10.1158/1078-0432.22483878.v1
https://doi.org/10.1158/1078-0432.22483878.v1
Autor:
Benjamin H. Lok, Geoffrey Liu, Ming S. Tsao, Aaron D. Schimmer, Rod Bremner, Joel D. Pearson, Samir H. Barghout, Vijithan Sugumar, Ranya Barayan, Jessica Weiss, Lifang Song, Fariha Rahman, Vidhyasagar Venkatasubramanian, Kevin C.J. Nixon, Mansi K. Aparnathi, Safa Majeed
Purpose:Small cell lung cancer (SCLC) is an aggressive disease with an overall 5-year survival rate of less than 10%. Treatment for SCLC with cisplatin/etoposide chemotherapy (C/E) ± radiotherapy has changed modestly over several decades. The ubiqui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62960533f4307a56243682fafcc1f621
https://doi.org/10.1158/1078-0432.c.6531261.v1
https://doi.org/10.1158/1078-0432.c.6531261.v1
Autor:
Safa Majeed, Mansi K. Aparnathi, Kevin C.J. Nixon, Vidhyasagar Venkatasubramanian, Fariha Rahman, Lifang Song, Jessica Weiss, Ranya Barayan, Vijithan Sugumar, Samir H. Barghout, Joel D. Pearson, Rod Bremner, Aaron D. Schimmer, Ming S. Tsao, Geoffrey Liu, Benjamin H. Lok
Publikováno v:
Clinical Cancer Research. 28:1966-1978
Purpose: Small cell lung cancer (SCLC) is an aggressive disease with an overall 5-year survival rate of less than 10%. Treatment for SCLC with cisplatin/etoposide chemotherapy (C/E) ± radiotherapy has changed modestly over several decades. The ubiqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfea56c4f506400bdeb1588b362d4102
https://doi.org/10.1158/1078-0432.ccr-21-0344
https://doi.org/10.1158/1078-0432.ccr-21-0344
Autor:
Sami Ul Haq, Sabine Schmid, Mansi K. Aparnathi, Katrina Hueniken, Luna J. Zhan, Danielle Sacdalan, Janice J.N. Li, Devalben Patel, Dangxiao Cheng, Vivek Philip, Geoffrey Liu, Scott V. Bratman, Benjamin H. Lok
Publikováno v:
Cancer Research. 82:3396-3396
Introduction: Small cell lung cancer (SCLC) is a deadly disease and patients often suffer from recurrent disease. Biologic mechanisms of recurrence are unclear. Epigenetic mechanisms, like DNA methylation, may be operant. SCLC is rarely resected; the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cb7b20960dfb4dbcc03fc6cb69ffa3c
https://doi.org/10.1158/1538-7445.am2022-3396
https://doi.org/10.1158/1538-7445.am2022-3396
Autor:
Jagdish S. Patel, Mansi K. Aparnathi
Publikováno v:
Bioscience Biotechnology Research Communications. 9:463-470
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68fd7c5f8f2f00189e2e060409d594ed
https://doi.org/10.21786/bbrc/9.3/18
https://doi.org/10.21786/bbrc/9.3/18
Autor:
Mansi K, Aparnathi, Jagdish S, Patel
Publikováno v:
Journal of stem cells. 11(3)
Therapeutic potential of adipose derived stem cells (ADSCs) has widely been explored for treatment of orthopedic ailments. Transplantation of cells encapsulated in a scaffold facilitates 3 dimensional modelling of the tissue for the cases where well-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9a1f9a419f14a3c847616ea9b662f9df
https://pubmed.ncbi.nlm.nih.gov/28296875
https://pubmed.ncbi.nlm.nih.gov/28296875
Autor:
Mansi K. Aparnathi, Rima Al-awar, Lifang Song, Ratheesh Subramaniam, Richard C. Marcellus, Benjamin H. Lok
Publikováno v:
Cancer Research. 79:3925-3925
Objective: Small cell lung cancer (SCLC) is a highly aggressive neuroendocrine malignancy. Post-platinum-based chemotherapy, rapid relapse of chemoresistant tumor is commonly seen. Unidentifiable causative mutations and from reversible nature of acqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69ddc35141b2d2b0e5230ffa89c1974e
https://doi.org/10.1158/1538-7445.am2019-3925
https://doi.org/10.1158/1538-7445.am2019-3925
Publikováno v:
Biotechnology Progress. 29:425-431
RNA interference represents one of the potential mechanisms of regulation of gene expression. Selective downregulation of myostatin (MSTN), a member of transforming growth factor-β (TGF-β) superfamily and a negative regulator of myogenesis, has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b42a388862ba5d9e2596cf51cbb8501
https://doi.org/10.1002/btpr.1681
https://doi.org/10.1002/btpr.1681