Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Mans, Broekgaarden"'
Autor:
Anne‐Laure Bulin, Mans Broekgaarden, Frédéric Chaput, Victor Baisamy, Jan Garrevoet, Benoît Busser, Dennis Brueckner, Antonia Youssef, Jean‐Luc Ravanat, Christophe Dujardin, Vincent Motto‐Ros, Frédéric Lerouge, Sylvain Bohic, Lucie Sancey, Hélène Elleaume
Publikováno v:
Advanced Science, Vol 7, Iss 20, Pp n/a-n/a (2020)
Abstract To improve the prognosis of glioblastoma, innovative radiotherapy regimens are required to augment the effect of tolerable radiation doses while sparing surrounding tissues. In this context, nanoscintillators are emerging radiotherapeutics t
Externí odkaz:
https://doaj.org/article/0d109878c2e542a3b14e42c6b5bc669c
Autor:
Nazareth Milagros Carigga Gutierrez, Núria Pujol-Solé, Qendresa Arifi, Jean-Luc Coll, Tristan le Clainche, Mans Broekgaarden
Publikováno v:
Cancer and Metastasis Reviews. 41:899-934
The dense cancer microenvironment is a significant barrier that limits the penetration of anticancer agents, thereby restraining the efficacy of molecular and nanoscale cancer therapeutics. Developing new strategies to enhance the permeability of can
Autor:
Tayyaba Hasan, Imran Rizvi, Edward V. Maytin, Mari Mino-Kenudson, Diane M. Simeone, Pushpamali De Silva, Yan Baglo, Mans Broekgaarden, Srivalleesha Mallidi, Huang-Chiao Huang, Michael Pigula, Sriram Anbil
Supplementary Methods Supplemental Figure 1: The MIA-PaCa-2 + PCAF model exhibits histologic features consistent with desmoplasia 90 days post implantation Supplemental Figure 2: 1 μM calcipitriol activates the vitamin D receptor (VDR) in cancer ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001caed6246fa8dbf16ec250549cd00e
https://doi.org/10.1158/1535-7163.22520601.v1
https://doi.org/10.1158/1535-7163.22520601.v1
Autor:
Tayyaba Hasan, Imran Rizvi, Edward V. Maytin, Mari Mino-Kenudson, Diane M. Simeone, Pushpamali De Silva, Yan Baglo, Mans Broekgaarden, Srivalleesha Mallidi, Huang-Chiao Huang, Michael Pigula, Sriram Anbil
Patients with cancer often confront the decision of whether to continue high-dose chemotherapy at the expense of cumulative toxicities. Reducing the dose of chemotherapy regimens while preserving efficacy is sorely needed to preserve the performance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e774c1d9962c91ce98c83f84e42ae64
https://doi.org/10.1158/1535-7163.c.6542694
https://doi.org/10.1158/1535-7163.c.6542694
Autor:
Megan J. Reiniers, Lianne R. de Haan, Laurens F. Reeskamp, Mans Broekgaarden, Rowan F. van Golen, Michal Heger
Publikováno v:
Antioxidants, Vol 10, Iss 5, p 674 (2021)
Numerous liver pathologies encompass oxidative stress as molecular basis of disease. The use of 2′,7′-dichlorodihydrofluorescein-diacetate (DCFH2-DA) as fluorogenic redox probe is problematic in liver cell lines because of membrane transport prot
Externí odkaz:
https://doaj.org/article/0ac759543ed44582b1bf42a92f2e21b1
Autor:
Tristan Le Clainche, Nazareth Milagros Carigga Gutierrez, Núria Pujol-Solé, Jean-Luc Coll, Mans Broekgaarden
Publikováno v:
Onco; Volume 2; Issue 1; Pages: 19-33
Photodynamic therapy (PDT) is a cancer treatment that relies on the remote-controlled activation of photocatalytic dyes (photosensitizers) in cancer tissues. To effectively treat cancer, a variety of pharmacological and optical parameters require opt
Publikováno v:
Cancers, Vol 12, Iss 9, p 2491 (2020)
Peritoneal carcinomatosis occurs frequently in patients with advanced stage gastrointestinal and gynecological cancers. The wide-spread peritoneal micrometastases indicate a poor outlook, as the tumors are difficult to diagnose and challenging to com
Externí odkaz:
https://doaj.org/article/b059e3a0a7ae42c19c8e5ecad012d47c
Autor:
Ghadir Kalot, Amélie Godard, Benoît Busser, Jacques Pliquett, Mans Broekgaarden, Vincent Motto-Ros, Karl David Wegner, Ute Resch-Genger, Ulli Köster, Franck Denat, Jean-Luc Coll, Ewen Bodio, Christine Goze, Lucie Sancey
Publikováno v:
Cells, Vol 9, Iss 9, p 1953 (2020)
Boron neutron capture therapy (BNCT) is a radiotherapeutic modality based on the nuclear capture of slow neutrons by stable 10B atoms followed by charged particle emission that inducing extensive damage on a very localized level (10B should accumulat
Externí odkaz:
https://doaj.org/article/9c7f289ec41e4680853ce03990b52aef
Autor:
Mans Broekgaarden, Ahmed Alkhateeb, Shazia Bano, Anne-Laure Bulin, Girgis Obaid, Imran Rizvi, Tayyaba Hasan
Publikováno v:
Cancers, Vol 12, Iss 6, p 1401 (2020)
Extensive desmoplasia is a hallmark of pancreatic ductal adenocarcinoma (PDAC), which frequently associates with treatment resistance. Recent findings indicate that a combination of photodynamic therapy and the multi-kinase inhibitor cabozantinib ach
Externí odkaz:
https://doaj.org/article/8414431ac6594bb1b8df4ebb8232f72e
Inhibition of NF-κB in Tumor Cells Exacerbates Immune Cell Activation Following Photodynamic Therapy
Autor:
Mans Broekgaarden, Milan Kos, Freek A. Jurg, Adriaan A. van Beek, Thomas M. van Gulik, Michal Heger
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 8, Pp 19960-19977 (2015)
Although photodynamic therapy (PDT) yields very good outcomes in numerous types of superficial solid cancers, some tumors respond suboptimally to PDT. Novel treatment strategies are therefore needed to enhance the efficacy in these therapy-resistant
Externí odkaz:
https://doaj.org/article/e4d2e410168d423f93a812d9a4b6947d