Zobrazeno 1 - 10
of 341
pro vyhledávání: '"Manrubia, Susanna"'
Autor:
Catalán, Pablo, García-Martín, Juan Antonio, Aguirre, Jacobo, Cuesta, José A., Manrubia, Susanna
All possible phenotypes are not equally accessible to evolving populations. In fact, only phenotypes of large size, i.e. those resulting from many different genotypes, are found in populations of sequences, presumably because they are easier to disco
Externí odkaz:
http://arxiv.org/abs/2304.05311
Autor:
Manrubia, Susanna
At odds with a traditional view of molecular evolution that seeks a descent-with-modification relationship between functional sequences, new functions can emerge {\it de novo} with relative ease. At early times of molecular evolution, random polymers
Externí odkaz:
http://arxiv.org/abs/2105.11784
Autor:
Zanette, Damián H., Manrubia, Susanna
Publikováno v:
Chaos 30, 033104 (2020)
We consider a class of multiplicative processes which, added with stochastic reset events, give origin to stationary distributions with power-law tails -- ubiquitous in the statistics of social, economic, and ecological systems. Our main goal is to p
Externí odkaz:
http://arxiv.org/abs/2105.11679
Autor:
Manrubia, Susanna, Zanette, Damián H.
Changes in human behavior are increasingly recognized as a major determinant of epidemic dynamics. Although collective activity can be modified through imposed measures to control epidemic progression, spontaneous changes can also arise as a result o
Externí odkaz:
http://arxiv.org/abs/2105.10572
Publikováno v:
Proceedings of the National Academy of Sciences (USA), 117, 26190-26196 (2020)
No, they can't. Epidemic spread is characterized by exponentially growing dynamics, which are intrinsically unpredictable. The time at which the growth in the number of infected individuals halts and starts decreasing cannot be calculated with certai
Externí odkaz:
http://arxiv.org/abs/2004.08842
Autor:
Manrubia, Susanna, Cuesta, José A., Aguirre, Jacobo, Ahnert, Sebastian E., Altenberg, Lee, Cano, Alejandro V., Catalán, Pablo, Diaz-Uriarte, Ramon, Elena, Santiago F., García-Martín, Juan Antonio, Hogeweg, Paulien, Khatri, Bhavin S., Krug, Joachim, Louis, Ard A., Martin, Nora S., Payne, Joshua L., Tarnowski, Matthew J., Weiß, Marcel
Publikováno v:
Physics of Life Reviews 38, 55-106 (2021)
Understanding how genotypes map onto phenotypes, fitness, and eventually organisms is arguably the next major missing piece in a fully predictive theory of evolution. We refer to this generally as the problem of the genotype-phenotype map. Though we
Externí odkaz:
http://arxiv.org/abs/2002.00363
Publikováno v:
Royal Society Open Science 7, 191813 (2020)
Every now and then the cultural paradigm of a society changes. Human history can be regarded as a sequence of long periods of cultural stasis punctuated by paradigm shifts that transform culture upside-down over the turn of a few generations. We prop
Externí odkaz:
http://arxiv.org/abs/1904.12972
Publikováno v:
Europhysics Letters 123, 28001 (2018)
The evolutionary dynamics of molecular populations are strongly dependent on the structure of genotype spaces. The map between genotype and phenotype determines how easily genotype spaces can be navigated and the accessibility of evolutionary innovat
Externí odkaz:
http://arxiv.org/abs/1806.03885
Pathogen transmission and virulence are main evolutionary variables broadly assumed to be linked through trade-offs. In well-mixed populations, these trade-offs are often ascribed to physiological restrictions, while populations with spatial self-str
Externí odkaz:
http://arxiv.org/abs/1804.08463