Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Manreet K. Chehal"'
Autor:
Israel Matos, Maunish Barvalia, Manreet K. Chehal, A. Gordon Robertson, Iva Kulic, Jessica A.F.D. Silva, Abhinandan Ranganathan, Amy Short, Yu-Hsuan Huang, Erin Long, John J. Priatel, Salim Dhanji, Brad H. Nelson, Danielle L. Krebs, Kenneth W. Harder
Publikováno v:
Cancer Research Communications. 3:404-419
While immunotherapies such as immune checkpoint blockade and adoptive T-cell therapy improve survival for a subset of human malignancies, many patients fail to respond. Phagocytes including dendritic cells (DC), monocytes, and macrophages (MF) orches
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c58b03e0d87c5b4e0ad543399513670
https://doi.org/10.1158/2767-9764.crc-22-0278
https://doi.org/10.1158/2767-9764.crc-22-0278
Autor:
Kenneth W. Harder, Danielle L. Krebs, Brad H. Nelson, Salim Dhanji, John J. Priatel, Erin Long, Yu-Hsuan Huang, Amy Short, Abhinandan Ranganathan, Jessica A.F.D. Silva, Iva Kulic, A. Gordon Robertson, Manreet K. Chehal, Maunish Barvalia, Israel Matos
Flow cytometry antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ec9a995ecaa9958ac355be08a4e49ab
https://doi.org/10.1158/2767-9764.22546750
https://doi.org/10.1158/2767-9764.22546750
Autor:
Kenneth W. Harder, Danielle L. Krebs, Brad H. Nelson, Salim Dhanji, John J. Priatel, Erin Long, Yu-Hsuan Huang, Amy Short, Abhinandan Ranganathan, Jessica A.F.D. Silva, Iva Kulic, A. Gordon Robertson, Manreet K. Chehal, Maunish Barvalia, Israel Matos
Supplementary Figure S1 shows the characterization of MT and MTG-CSF-/- cell lines and tumors, including surface protein expression, tumor volume/weight, and immune cell subset content. Composition of immune cells in blood and spleen of MT and MTG-CS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4966f5bc3a991561c45cd11aa6dd401f
https://doi.org/10.1158/2767-9764.22546768
https://doi.org/10.1158/2767-9764.22546768
Autor:
Kenneth W. Harder, Danielle L. Krebs, Brad H. Nelson, Salim Dhanji, John J. Priatel, Erin Long, Yu-Hsuan Huang, Amy Short, Abhinandan Ranganathan, Jessica A.F.D. Silva, Iva Kulic, A. Gordon Robertson, Manreet K. Chehal, Maunish Barvalia, Israel Matos
Supplementary Figure S3 shows deep phenotyping of Neut/MDSCs and B cells in the bone marrow of mice bearing MT or MTG-CSF-/- tumors, using FlowSOM applied in tSNE maps.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c8c0f73ead8b30f58ce885afd185c9
https://doi.org/10.1158/2767-9764.22546759
https://doi.org/10.1158/2767-9764.22546759
Autor:
Kenneth W. Harder, Danielle L. Krebs, Brad H. Nelson, Salim Dhanji, John J. Priatel, Erin Long, Yu-Hsuan Huang, Amy Short, Abhinandan Ranganathan, Jessica A.F.D. Silva, Iva Kulic, A. Gordon Robertson, Manreet K. Chehal, Maunish Barvalia, Israel Matos
Supplementary Figure S2 compares the immune cell content in peripheral blood and spleens from immunocompetent, immunocompromised and G-CSFR-/- mice harboring MT or MTG-CSF-/- tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad9566fed7c1d54831812bddbdba8aa
https://doi.org/10.1158/2767-9764.22546765.v1
https://doi.org/10.1158/2767-9764.22546765.v1
Autor:
Kenneth W. Harder, Danielle L. Krebs, Brad H. Nelson, Salim Dhanji, John J. Priatel, Erin Long, Yu-Hsuan Huang, Amy Short, Abhinandan Ranganathan, Jessica A.F.D. Silva, Iva Kulic, A. Gordon Robertson, Manreet K. Chehal, Maunish Barvalia, Israel Matos
CyTOF panels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a30dceefceb20ad74c8062fe9380b34
https://doi.org/10.1158/2767-9764.22546753.v1
https://doi.org/10.1158/2767-9764.22546753.v1
Autor:
Kenneth W. Harder, Danielle L. Krebs, Brad H. Nelson, Salim Dhanji, John J. Priatel, Erin Long, Yu-Hsuan Huang, Amy Short, Abhinandan Ranganathan, Jessica A.F.D. Silva, Iva Kulic, A. Gordon Robertson, Manreet K. Chehal, Maunish Barvalia, Israel Matos
While immunotherapies such as immune checkpoint blockade and adoptive T-cell therapy improve survival for a subset of human malignancies, many patients fail to respond. Phagocytes including dendritic cells (DC), monocytes, and macrophages (MF) orches
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b701a55c408a41306b8541cf640048d
https://doi.org/10.1158/2767-9764.c.6551242
https://doi.org/10.1158/2767-9764.c.6551242
Autor:
Kenneth W. Harder, Danielle L. Krebs, Tomasz Cierpicki, Jolanta Grembecka, Brad H. Nelson, Morgan E. Roberts, Xueling Fan, Kevin Tsai, Manreet K. Chehal, Alexander Sio
PDF file, 353K, Supplemental Figure S1: Mammary tumors induce significant changes in granulocyte and monocyte numbers in mice. Supplemental Figure S2: 4T1 tumor development is associated with impaired BM myelopoiesis and erythropoiesis, and disrupts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba4ce2d9eb65c9dfb7f7e7efc3823b23
https://doi.org/10.1158/0008-5472.22396644.v1
https://doi.org/10.1158/0008-5472.22396644.v1
Autor:
Kenneth W. Harder, Danielle L. Krebs, Tomasz Cierpicki, Jolanta Grembecka, Brad H. Nelson, Morgan E. Roberts, Xueling Fan, Kevin Tsai, Manreet K. Chehal, Alexander Sio
Cancer is associated with immune dysfunction characterized by the presence of proinflammatory and immunosuppressive cells and factors that contribute to tumor growth and progression. Here we show that mammary tumor growth is associated with defects i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c1ab1d44a57173c59ef8c3900f46865
https://doi.org/10.1158/0008-5472.c.6504621
https://doi.org/10.1158/0008-5472.c.6504621
Autor:
Gary P. Anderson, Mei Lin Da, Margaret L. Hibbs, Manreet K. Chehal, Danielle L. Krebs, Jessica E Jones, Melissa Inglese, Pascal Ziltener, Alexander Sio, John J. Priatel, Nicole Kountouri, David M. Tarlinton, Nicholas D. Huntington, Kenneth W. Harder
Publikováno v:
The Journal of Immunology. 188:5094-5105
The innate immune response is a first line of defense against invading pathogens; however, the magnitude of this response must be tightly regulated, as hyper- or suboptimal responses can be detrimental to the host. Systemic inflammation resulting fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c69f9aefc3aaeaa478af03e3435dd65
https://doi.org/10.4049/jimmunol.1103395
https://doi.org/10.4049/jimmunol.1103395