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Dominant Role for Regulatory T Cells in Protecting Females Against Pulmonary Hypertension

Autor: Tamosiuniene, Rasa, Manouvakhova, Olga, Mesange, Paul, Saito, Toshie, Qian, Jin, Sanyal, Mrinmoy, Lin, Yu-Chun, Nguyen, Linh P, Luria, Amir, Tu, Allen B, Sante, Joshua M, Rabinovitch, Marlene, Fitzgerald, Desmond J, Graham, Brian B, Habtezion, Aida, Voelkel, Norbert F, Aurelian, Laure, Nicolls, Mark R

Publikováno v: Circulation research, vol 122, iss 12

RationalePulmonary arterial hypertension (PH) is a life-threatening condition associated with immune dysregulation and abnormal regulatory T cell (Treg) activity, but it is currently unknown whether and how abnormal Treg function differentially affec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::8f59282ca5a21eee8bc669498dcb26cf
https://escholarship.org/uc/item/6pw4t054

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Dominant Role for Regulatory T Cells in Protecting Females Against Pulmonary Hypertension.

Autor: Tamosiuniene R; From the Stanford University School of Medicine, Department of Medicine, CA (R.T., P.M., T.S., J.Q., M.S., L.P.N., A.L., M.R., A.H., L.A., M.R.N.)., Manouvakhova O; VA Palo Alto Health Care System, CA (O.M., Y.-C.L., A.L., A.B.T., J.M.S., M.R.N.)., Mesange P; From the Stanford University School of Medicine, Department of Medicine, CA (R.T., P.M., T.S., J.Q., M.S., L.P.N., A.L., M.R., A.H., L.A., M.R.N.)., Saito T; From the Stanford University School of Medicine, Department of Medicine, CA (R.T., P.M., T.S., J.Q., M.S., L.P.N., A.L., M.R., A.H., L.A., M.R.N.)., Qian J; From the Stanford University School of Medicine, Department of Medicine, CA (R.T., P.M., T.S., J.Q., M.S., L.P.N., A.L., M.R., A.H., L.A., M.R.N.)., Sanyal M; From the Stanford University School of Medicine, Department of Medicine, CA (R.T., P.M., T.S., J.Q., M.S., L.P.N., A.L., M.R., A.H., L.A., M.R.N.)., Lin YC; VA Palo Alto Health Care System, CA (O.M., Y.-C.L., A.L., A.B.T., J.M.S., M.R.N.)., Nguyen LP; From the Stanford University School of Medicine, Department of Medicine, CA (R.T., P.M., T.S., J.Q., M.S., L.P.N., A.L., M.R., A.H., L.A., M.R.N.)., Luria A; From the Stanford University School of Medicine, Department of Medicine, CA (R.T., P.M., T.S., J.Q., M.S., L.P.N., A.L., M.R., A.H., L.A., M.R.N.).; VA Palo Alto Health Care System, CA (O.M., Y.-C.L., A.L., A.B.T., J.M.S., M.R.N.)., Tu AB; VA Palo Alto Health Care System, CA (O.M., Y.-C.L., A.L., A.B.T., J.M.S., M.R.N.)., Sante JM; VA Palo Alto Health Care System, CA (O.M., Y.-C.L., A.L., A.B.T., J.M.S., M.R.N.)., Rabinovitch M; From the Stanford University School of Medicine, Department of Medicine, CA (R.T., P.M., T.S., J.Q., M.S., L.P.N., A.L., M.R., A.H., L.A., M.R.N.)., Fitzgerald DJ; University of Limerick, President, Ireland (D.J.F.)., Graham BB; University of Colorado Denver, School of Medicine, Department of Medicine, Aurora (B.B.G.)., Habtezion A; From the Stanford University School of Medicine, Department of Medicine, CA (R.T., P.M., T.S., J.Q., M.S., L.P.N., A.L., M.R., A.H., L.A., M.R.N.)., Voelkel NF; Virginia Commonwealth University School of Medicine, Department of Internal Medicine, Richmond (N.F.V.)., Aurelian L; From the Stanford University School of Medicine, Department of Medicine, CA (R.T., P.M., T.S., J.Q., M.S., L.P.N., A.L., M.R., A.H., L.A., M.R.N.).; University of Maryland School of Medicine, Baltimore (L.A.)., Nicolls MR; From the Stanford University School of Medicine, Department of Medicine, CA (R.T., P.M., T.S., J.Q., M.S., L.P.N., A.L., M.R., A.H., L.A., M.R.N.) mnicolls@stanford.edu.; VA Palo Alto Health Care System, CA (O.M., Y.-C.L., A.L., A.B.T., J.M.S., M.R.N.).

Publikováno v: Circulation research [Circ Res] 2018 Jun 08; Vol. 122 (12), pp. 1689-1702. Date of Electronic Publication: 2018 Mar 15.