NEDD4 degrades TUSC2 to promote glioblastoma progression

Autor: Rimkus, Tadas K., Arrigo, Austin B., Zhu, Dongqin, Carpenter, Richard L., Sirkisoon, Sherona, Doheny, Daniel, Regua, Angelina T., Wong, Grace L., Manore, Sara, Wagner, Calvin, Lin, Hui-Kuan, Jin, Guangxu, Ruiz, Jimmy, Chan, Michael, Debinski, Waldemar, Lo, Hui-Wen

Publikováno v: In Cancer Letters 10 April 2022 531:124-135

An FDA-Approved Antifungal, Ketoconazole, and Its Novel Derivative Suppress tGLI1-Mediated Breast Cancer Brain Metastasis by Inhibiting the DNA-Binding Activity of Brain Metastasis-Promoting Transcription Factor tGLI1.

Autor: Doheny, Daniel¹ (AUTHOR), Manore, Sara¹ (AUTHOR), Sirkisoon, Sherona R.¹ (AUTHOR), Zhu, Dongqin¹ (AUTHOR), Aguayo, Noah R.¹ (AUTHOR), Harrison, Alexandria¹ (AUTHOR), Najjar, Mariana¹ (AUTHOR), Anguelov, Marlyn¹ (AUTHOR), Cox, Anderson O'Brien² (AUTHOR), Furdui, Cristina M.^2,3,4 (AUTHOR), Watabe, Kounosuke^1,4 (AUTHOR), Hollis, Thomas^4,5 (AUTHOR), Thomas, Alexandra^4,6 (AUTHOR), Strowd, Roy^4,7 (AUTHOR), Lo, Hui-Wen^1,4 (AUTHOR) hlo@wakehealth.edu

Publikováno v: Cancers. Sep2022, Vol. 14 Issue 17, p4256. 21p.

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Design, synthesis and analysis of novel sphingosine kinase-1 inhibitors to improve oral bioavailability

Autor: Butler, Kendarius J., Castro, Angel A., Dwyer, Tiffany S., Hardwick, Louise M., Iacino, Melody C., Manore, Sara G., Mays, Kevin M., McGlade, Caylie A., Hair, Lisa N., Parker, Erin W., Smith, Mikala R., Turnow, Morgan T., Wilson, Matthew R., Woodson, Stephanie R., Cotham, William E., Walla, Michael D., Hurlbert, Jason C., Christian Grattan, T.

Publikováno v: In Bioorganic & Medicinal Chemistry Letters 15 October 2021 50

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