Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Manon Wiersma"'
Autor:
Nhi T. Tran, Nadia Hale, Anawar Aung Win Maung, Manon Wiersma, David W. Walker, Graeme Polglase, Margie Castillo-Melendez, Flora Y. Wong
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-16 (2024)
Abstract Background Intrauterine inflammation is considered a major cause of brain injury in preterm infants, leading to long-term neurodevelopmental deficits. A potential contributor to this brain injury is dysregulation of neurovascular coupling. W
Externí odkaz:
https://doaj.org/article/47540c476b82405f889a6287862d3e8a
Autor:
Nhi T Tran, James T. Pearson, Graeme R. Polglase, Anton Maksimenko, Ishmael Miguel Inocencio, Flora Y. Wong, Song J. Khor, Shinji Nakamura, Manon Wiersma, Katja Stoecker, David W. Walker
Publikováno v:
J Cereb Blood Flow Metab
Neurovascular coupling has been well-defined in the adult brain, but variable and inconsistent responses have been observed in the neonatal brain. The mechanisms that underlie functional haemodynamic responses in the developing brain are unknown. Syn
Autor:
Ishmael M. Inocencio, Nhi T. Tran, Manon Wiersma, Katja Stoecker, Shinji Nakamura, Timothy J. Moss, David W. Walker, Flora Y. Wong
Publikováno v:
Experimental Neurology. 352:114049
Neurovascular coupling leads to an increase in local cerebral blood flow and oxygenation in response to increased neural activity. Reduced cerebral functional responses may predispose to tissue hypoxia when neural activity is increased. Intrauterine
Autor:
Flora Y. Wong, Nhi T. Tran, Manon Wiersma, David W. Walker, Song J. Khor, Ishmael M. Inocencio, Shinji Nakamura
Publikováno v:
Experimental neurology. 341
Background In the adult brain, increases in neural activity lead to increases in local blood flow. However, in the preterm neonate, studies of cerebral functional haemodynamics have yielded inconsistent results, including negative responses suggestin
Autor:
Flora Y. Wong, Nhi Thao Tran, James T. Pearson, Katja Stoecker, Shinji Nakamura, Song J. Khor, Ishmael Miguel Inocencio, Manon Wiersma, Graeme R. Polglase
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 129(5)
Positive end-expiratory pressure (PEEP) improves oxygenation in mechanically ventilated preterm neonates by preventing lung collapse. However, high PEEP may alter cerebral blood flow secondarily to the increased intrathoracic pressure, predisposing t