Metabolic adaptation towards glycolysis supports resistance to neoadjuvant chemotherapy in early triple negative breast cancers

Autor: Françoise Derouane, Manon Desgres, Camilla Moroni, Jérôme Ambroise, Martine Berlière, Mieke R. Van Bockstal, Christine Galant, Cédric van Marcke, Marianela Vara-Messler, Stefan J. Hutten, Jos Jonkers, Larissa Mourao, Colinda L. G. J. Scheele, Francois P. Duhoux, Cyril Corbet

Publikováno v: Breast Cancer Research, Vol 26, Iss 1, Pp 1-19 (2024)

Abstract Background Neoadjuvant chemotherapy (NAC) is the standard of care for patients with early-stage triple negative breast cancers (TNBC). However, more than half of TNBC patients do not achieve a pathological complete response (pCR) after NAC,

Externí odkaz: https://doaj.org/article/cbcb7ddcc69b4cbbb96f42be1600415c

Rbm24 displays dynamic functions required for myogenic differentiation during muscle regeneration

Autor: Raphaëlle Grifone, Audrey Saquet, Manon Desgres, Claudia Sangiorgi, Caterina Gargano, Zhenlin Li, Dario Coletti, De-Li Shi

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)

Abstract Skeletal muscle has a remarkable capacity of regeneration after injury, but the regulatory network underlying this repair process remains elusive. RNA-binding proteins play key roles in the post-transcriptional regulation of gene expression

Externí odkaz: https://doaj.org/article/7e2df0f3ea7e404ead019033bc8f3956

Extracellular vesicles from human cardiovascular progenitors trigger a reparative immune response in infarcted hearts

Autor: Sisareuth Tan, Jean-Sébastien Silvestre, Kamaleswaran Keirththana, Alain Brisson, Thi Anh-Dao Tran, José Vilar, Philippe Menasché, Paul Alayrac, Thomas Hamada, Maria Franca Perotto, Nadia El Harane, Reem Al-Daccak, Dominique Charron, Laetitia Pidial, Valérie Bellamy, Nisa Renault, Hocine Rachid Hocine, Chloé Guillas, Manon Desgres, Ingrid Gomez, Bruna Lima Correa

Publikováno v: Cardiovascular Research
Cardiovascular Research, Oxford University Press (OUP), 2020, pp.cvaa028. ⟨10.1093/cvr/cvaa028⟩
Cardiovascular Research, 2020, pp.cvaa028. ⟨10.1093/cvr/cvaa028⟩

AimsThe cardioprotective effects of human induced pluripotent stem cell-derived cardiovascular progenitor cells (CPC) are largely mediated by the paracrine release of extracellular vesicles (EV). We aimed to assess the immunological behaviour of EV-C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8005c68d96df6fd43058ccc331c80b6
https://doi.org/10.1093/cvr/cvaa028

Rbm24 Displays Dynamic Functions Required for Myogenic Differentiation During Muscle Regeneration

Autor: Caterina Gargano, Manon Desgres, De-Li Shi, Zhenlin Li, Claudia Sangiorgi, Dario Coletti, Raphaëlle Grifone, Audrey Saquet

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2021, 11 (1), pp.9423. ⟨10.1038/s41598-021-88563-3⟩
Scientific Reports, 2021, 11 (1), pp.9423. ⟨10.1038/s41598-021-88563-3⟩

Skeletal muscle has a remarkable capacity of regeneration after injury, but the regulatory network underlying this repair process remains elusive. RNA-binding proteins play key roles in the post-transcriptional regulation of gene expression and the m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c33bba97f75d159319c371ed8ac3ad
https://doi.org/10.21203/rs.3.rs-129292/v1

Clinical Translation of Pluripotent Stem Cell Therapies: Challenges and Considerations

Autor: Manon Desgres, Philippe Menasché

Publikováno v: Cell Stem Cell
Cell Stem Cell, Cambridge, MA : Cell Press, 2019, 25, pp.594-606. ⟨10.1016/j.stem.2019.10.001⟩

Although the clinical outcomes of cell therapy trials have not met initial expectations, emerging evidence suggests that injury-mediated tissue damage might benefit from the delivery of cells or their secreted products. Pluripotent stem cells (PSCs)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aa30b7de5084c1f889127e6ec69ec04
https://hal.archives-ouvertes.fr/hal-03489221