Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Manon Bosseler"'
Autor:
Muhammad Zaeem Noman, Irene Adelaide Bocci, Manale Karam, Kris Van Moer, Manon Bosseler, Akinchan Kumar, Guy Berchem, Christian Auclair, Bassam Janji
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Harmine is a dual-specificity tyrosine-regulated kinase 1A (DYRK1A) inhibitor that displays a number of biological and pharmacological properties. Also referred to as ACB1801 molecule, we have previously reported that harmine increases the presentati
Externí odkaz:
https://doaj.org/article/d3916eff71a8457593b72dfca6856050
Autor:
Delphine Sauvage, Manon Bosseler, Elodie Viry, Georgia Kanli, Anais Oudin, Guy Berchem, Olivier Keunen, Bassam Janji
Publikováno v:
Cells, Vol 11, Iss 18, p 2783 (2022)
Anti-programmed death 1 (PD-1) is a revolutionary treatment for many cancers. The response to anti-PD-1 relies on several properties of tumor and immune cells, including the expression of PD-L1 and PD-1. Despite the impressive clinical benefit achiev
Externí odkaz:
https://doaj.org/article/0520fbadde834acaa63516fc834d000e
Autor:
Nassera Aouali, Angeliki Broukou, Manon Bosseler, Olivier Keunen, Vincent Schlesser, Bassam Janji, Valerie Palissot, Philippe Stordeur, Guy Berchem
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130339 (2015)
Epigenetic modifications play a major role in the development of multiple myeloma. We have previously reported that the PPARγ agonist pioglitazone (PIO) enhances, in-vitro, the cytotoxic effect of the Histone deacetylase inhibitor (HDACi), valproic
Externí odkaz:
https://doaj.org/article/4618f31380ff4482bcd7a6a0a2546720
Autor:
Kris Van Moer, Tsolere Arakelian, Meriem Hasmim, Salem Chouaib, Manon Bosseler, Alice Benoit, Audrey Lequeux, Bassam Janji, Muhammad Zaeem Noman, Guy Berchem, Elodie Viry, Malina Xiao
Publikováno v:
Oncogene
Hypoxia is a key factor responsible for the failure of therapeutic response in most solid tumors and promotes the acquisition of tumor resistance to various antitumor immune effectors. Reshaping the hypoxic immune suppressive tumor microenvironment t
Autor:
Markus Ollert, Malina Xiao, Martyna Szpakowska, Bassam Janji, Ludovic Ménard, Andy Chevigné, Muhammad Zaeem Noman, Manon Bosseler, Guy Berchem
Publikováno v:
Critical Reviews™ in Oncogenesis. 23:321-332
Autophagy is a quality control process executed at the basal level in almost all cell types. However, in cancer cells, autophagy is activated by several stimuli, including hypoxia. Depending on tumor type, stage, and genetic context, autophagy is a d
Autor:
Irene Bocci, Malina Xiao, Kris Van Moer, Delphine Sauvage, Meriem Hasmim, Bassam Janji, Guy Berchem, Muhammad Zaeem Noman, Manon Bosseler, Audrey Lequeux, Elodie Viry
Publikováno v:
Cancer letters. 458
Compared to traditional therapies, such as surgery, radio-chemotherapy, or targeted approaches, immunotherapies based on immune checkpoint blockers (ICBs) have revolutionized the treatment of cancer. Although ICBs have yielded long-lasting results an
Autor:
Angelina Broukou, Vincent Schlesser, Manon Bosseler, Amandine Lequeux, Bassam Janji, Nassera Aouali, Guy Berchem, Tony Kaoma, Jean-Hugues François, Vanessa Marani, Valérie Palissot
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 19; Issue 6; Pages: 1551
International Journal of Molecular Sciences; Volume 19; Issue 6; Pages: 1551
The introduction of novel frontline agents in multiple myeloma (MM), like immunomodulatory drugs and proteasome inhibitors, has improved the overall survival of patients. Yet, MM is still not curable, and drug resistance (DR) remains the main challen
Publikováno v:
Hypoxia and Human Diseases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24229f54859b4e7235de3ef3c788d856
http://www.intechopen.com/articles/show/title/the-critical-role-of-hypoxia-in-tumor-mediated-immunosuppression
http://www.intechopen.com/articles/show/title/the-critical-role-of-hypoxia-in-tumor-mediated-immunosuppression
Autor:
Victoria El-Khoury, Guy Berchem, Kris Van Moer, Etienne Moussay, Manon Bosseler, Valérie Palissot, Sandrine Pierson, Bassam Janji, Laurent Kellner, Nicolaas H. C. Brons, Nassera Aouali
Publikováno v:
British Journal of Haematology. 147:662-671
The main challenge in using chemotherapy to treat multiple myeloma (MM) is drug resistance. In order to evaluate the anti-neoplastic properties of a new drug combination in MM, two clinically available drugs, valproic acid (VPA) a histone deacetylase
Autor:
Vincent Schlesser, Bassam Janji, Angeliki Broukou, Nassera Aouali, Manon Bosseler, Olivier Keunen, Philippe Stordeur, Guy Berchem, Valérie Palissot
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130339 (2015)
PLoS ONE
PLoS ONE
Epigenetic modifications play a major role in the development of multiple myeloma. We have previously reported that the PPARγ agonist pioglitazone (PIO) enhances, in-vitro, the cytotoxic effect of the Histone deacetylase inhibitor (HDACi), valproic