Oncogene-Induced Reprogramming in Acute Lymphoblastic Leukemia: Towards Targeted Therapy of Leukemia-Initiating Cells

Autor: Vincent Fregona, Manon Bayet, Bastien Gerby

Publikováno v: Cancers
Cancers, MDPI, 2021, 13 (21), pp.5511. ⟨10.3390/cancers13215511⟩
Cancers, 2021, 13 (21), pp.5511. ⟨10.3390/cancers13215511⟩
Cancers, Vol 13, Iss 5511, p 5511 (2021)

Simple Summary Acute lymphoblastic leukemia is a heterogeneous disease characterized by a diversity of genetic alterations, following a sophisticated and controversial organization. In this review, we present and discuss the concepts exploring the ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2994e72ba10b1e5ee10d464378b6186f
https://hal.archives-ouvertes.fr/hal-03420678/document

New Approach to Decipher GATA2 Deficiency Syndrome: Focus on the Recurrent GATA2 R396Q Mutation

Autor: Esmaa Sellam, Vincent Fregona, Cyril Broccardo, Naïs Prade, Laetitia Largeaud, Camille Hamelle, Stephanie Dufrechou, Manon Bayet, Christine Didier, Eric Delabesse, Sylvie Hébrard, Marlène Pasquet, Laura Jamrog, Bastien Gerby

Publikováno v: Blood. 138:27-27

Germline GATA2 mutations are identified in a complex disorder termed GATA2 deficiency syndrome. Clinical heterogeneous manifestations are associated with a wide diversity of molecular alterations (missense, frameshift, nonsense, intronic or splicing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c0dc3b780aaefb90418fce2b207a7dfc
https://doi.org/10.1182/blood-2021-148307