Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Manolis Georgarakis"'
Autor:
Sofia A. Papadimitriou, Dimitrios N. Bikiaris, Manolis Georgarakis, George Z. Papageorgiou, Feras Imad Kanaze
Publikováno v:
Journal of Nanomaterials, Vol 2009 (2009)
Biocompatible poly(propylene-co-butylene succinate) (PPBSu) copolyesters, containing up to 50 mol% butylene succinate units, were synthesized by the two-stage melt polycondensation method (esterification and polycondensation). The copolymers were ful
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 95:903-915
In this work, the enhancement of drug dissolution rate through the preparation of new formulations containing Nimodipine in molecular level dispersion or in nanodispersion into poly(vinyl pyrrolidone) (PVP) matrix, was investigated. Differential scan
Autor:
Sofia A. Papadimitriou, Manolis Georgarakis, Konstantinos Avgoustakis, Evangelos Karavas, Dimitrios N. Bikiaris
Publikováno v:
Carbohydrate Polymers. 73:44-54
Chitosan (CS) nanoparticles of dorzolamide hydrochloride (Dorzo) and pramipexole hydrochloride (Prami) were prepared by the ionic gelation method and their in vitro properties were studied. The long-term objective is the development of efficient ocul
Publikováno v:
International Journal of Pharmaceutics. 340:76-83
The aim of the present study was to experimentally examine whether poorly water-soluble drugs dispersed in a polymeric matrix exist as amorphous nanodispersions or molecularly dispersed compounds. Felodipine (Felo) dispersed in PVP matrix (solid disp
Publikováno v:
European Journal of Pharmaceutical Sciences. 30:1-6
The objective of the present investigations was to develop oblong tablets which expand after contact with gastrointestinal fluids within a few minutes to a length of 4-6 cm and which should remain in the stomach for a prolonged period of time due to
Publikováno v:
European Journal of Clinical Nutrition. 61:472-477
Hesperetin and naringenin, the aglycones of the flavanone glycosides hesperidin and naringin, occur naturally in citrus fruits. They exert interesting pharmacological properties such as antioxidant, anti-inflammatory, blood lipid and cholesterol lowe
Autor:
A.C. Stergiou, Feras Imad Kanaze, Manolis Georgarakis, Dimitrios N. Bikiaris, Ioannis Niopas, Eugene Kokkalou
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 83:283-290
Purposes of this paper were to prepare and study new drug delivery systems for both flavanone glycosides and their aglycones based on solid-dispersion systems. These compounds are poor water soluble drugs, so an enhancement of their dissolution is a
Autor:
Manolis Georgarakis, Ioannis Niopas, Feras Imad Kanaze, A.C. Stergiou, Eugene Kokkalou, Dimitrios N. Bikiaris
Publikováno v:
Journal of Applied Polymer Science. 102:460-471
Polyvinylpyrrolidone (PVP) and poly(ethylene glycol) (PEG) solid dispersion systems with flavanone glycosides, naringin and hesperidin, and their aglycones, naringenin and hesperetin, were prepared, using solvent evaporation method, to enhance their
Autor:
George Z. Papageorgiou, Evangelos Karavas, A.C. Stergiou, Eleni Pavlidou, Ferras Kanaze, Manolis Georgarakis, Dimitrios N. Bikiaris
Publikováno v:
Thermochimica Acta. 439:58-67
Polyvinylpyrrolidone (PVP) and poly(ethylene glycol) (PEG) solid dispersions with Felodipine or Hesperetin having up to 20 wt% drug were prepared using solvent evaporation method. Solid dispersions in comparison with their physical mixtures were stud
Publikováno v:
Journal of Chromatography B. 783:425-432
In this study, a sensitive, specific, precise and accurate method for lisonopril quantitative determination in human serum was developed and validated. The method comprises lisinopril isolation from serum by means of solid-phase extraction followed b