Zobrazeno 1 - 10
of 437
pro vyhledávání: '"Manojit, Pal"'
Autor:
Manam Sreenivasa Rao, Meda Haritha, N. Chandrasekhar, Mandava V. Basaveswara Rao, Manojit Pal
Publikováno v:
Arabian Journal of Chemistry, Vol 12, Iss 8, Pp 2697-2703 (2019)
Designed as potential cytotoxic agents a series of 6-substituted 2,3-dihydro-1H-pyrrolo[3,2,1-ij]quinoline derivatives were synthesized by using a Bischler type reaction. The methodology involved the cyclodehydration of 2-(3,4-dihydroquinolin-1(2H)-y
Externí odkaz:
https://doaj.org/article/eafc3eeef1bf481b844a61f4a1864b9a
Publikováno v:
Arabian Journal of Chemistry, Vol 12, Iss 8, Pp 3911-3920 (2019)
A new and greener approach has been developed for the direct and one-pot synthesis of 2-aryl substituted N-(4-oxo-1,2-dihydroquinazolin-3(4H)-yl)aryl or alkylamide derivatives. The methodology involved reaction of isatoic anhydride, acid hydrazides a
Externí odkaz:
https://doaj.org/article/69c2cfd65a734269a34165cf901db7f4
Publikováno v:
Arabian Journal of Chemistry, Vol 12, Iss 8, Pp 3667-3677 (2019)
In view of known antitumor and cytotoxic properties of 2- and 3-pyridinyl substituted indole derivatives, respectively a number of isomeric N-pyridinyl substituted indoles and their analogs were synthesized as potential cytotoxic agents. A greener ap
Externí odkaz:
https://doaj.org/article/b3871e056c3a41d3b74e9a15728de77d
Publikováno v:
Arabian Journal of Chemistry, Vol 12, Iss 8, Pp 4189-4196 (2019)
A convenient synthetic method has been developed for accessing 2,6-dialkynyl-3,5-dichloropyridine derivatives in acceptable to good yields. The methodology involved ultrasound assisted site-selective alkynylation of 2,3,5,6-tetrachloropyridines under
Externí odkaz:
https://doaj.org/article/31cab8d6eaa1493ba88137ad1e67bc4c
Publikováno v:
Arabian Journal of Chemistry, Vol 12, Iss 8, Pp 2749-2759 (2019)
Prompted by the literature report on anticancer properties of mefenamic acid, a series of mefenamic acid based indole derivatives were designed via a rational approach. Synthesis of this class of compounds was carried out via a 3-step method starting
Externí odkaz:
https://doaj.org/article/e2b380fea6fd4eb5be81af769f252b4c
Autor:
Namburi Suresh, Gutta Lakshmi Prasanna, A. Ratnakar, Mandava Venkata Basaveswara Rao, Manojit Pal
Publikováno v:
Arabian Journal of Chemistry, Vol 12, Iss 8, Pp 5370-5379 (2019)
An ultrasound assisted method has been developed for the Pd-mediated synthesis of indole derivatives in good to acceptable yields. The methodology involved Pd/C-catalyzed coupling–cyclization of 2-iodosulfanilide with alkynes under ultrasound irrad
Externí odkaz:
https://doaj.org/article/6942eeb81a0f407893feb3f5c3c6a078
Publikováno v:
Arabian Journal of Chemistry, Vol 12, Iss 8, Pp 3836-3846 (2019)
The Pd/C–PPh3 catalyst system facilitated the C–C bond forming reaction between 3-iodo-1-methyl-1H-indole and various terminal alkenes under ultrasound irradiation. The present ultrasound assisted Mizoroki–Heck coupling afforded a number of 3-v
Externí odkaz:
https://doaj.org/article/7724fdacc51640479b7466c0e3efac78
Publikováno v:
Arabian Journal of Chemistry, Vol 12, Iss 8, Pp 4320-4330 (2019)
A one-pot protocol based on coupling-cyclization strategy has been developed for the construction of indole ring leading to 2-substituted indole derivatives. The methodology involved ultrasound assisted Mizoroki–Heck coupling in the initial step fo
Externí odkaz:
https://doaj.org/article/b331cc5ded92406cb84a2d302139b5e9
Publikováno v:
Arabian Journal of Chemistry, Vol 12, Iss 8, Pp 4220-4230 (2019)
Pd/C facilitated Suzuki–Miyaura coupling of 2-aryl-3-bromoflavones with 4,4-disubstituted (1,4-dihydro-2-oxo-2H-3,1-benzoxazin-6-yl)boronic acids under ultrasound irradiation. The methodology involving the use of 10%Pd/C-TBAB-K2CO3 system in DMF/H2
Externí odkaz:
https://doaj.org/article/90256298850c4616b503899dc27dd2fe
Autor:
Bethala Jawahar Luther, Chekuri Sharmila Rani, Namburi Suresh, Mandava V. Basaveswara Rao, Ravikumar Kapavarapu, Chakali Suresh, P. Vijaya Babu, Manojit Pal
Publikováno v:
Arabian Journal of Chemistry, Vol 12, Iss 8, Pp 3108-3117 (2019)
A series of novel hybrid molecules were designed rationally by connecting an indole moiety with a quinoxaline ring through a linker as potential inhibitors of PDE4. Their design was validated initially in silico by performing docking studies using a
Externí odkaz:
https://doaj.org/article/56da9551b68646ef9ec132a07a900e53