Zobrazeno 1 - 10
of 12 536
pro vyhledávání: '"Manoj M."'
Autor:
Matthew S. Jeffers, Cheng En Xi, Raj Bapuji, Hannah Wotherspoon, Jonathan Kimmelman, Patrick Bedford, Daniel I. McIsaac, Manoj M. Lalu, Dean A. Fergusson
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Regulatory applications for cell therapy face more objections compared to conventional small molecule or biological drugs, leading to delays in market approval and clinical adoption. Increased regulatory objections frequently rela
Externí odkaz:
https://doaj.org/article/7044491a50f94be9b8a292b7553bc30e
Publikováno v:
CJC Open, Vol 6, Iss 7, Pp 893-900 (2024)
Background: Embracing patient viewpoints can enhance the translation of novel therapeutics to clinical settings. This study evaluated the acceptability of using extracellular vesicles (EVs) as a biological therapy for preventing postoperative atrial
Externí odkaz:
https://doaj.org/article/2694576a7c9146e9b3319f761ed67c82
Autor:
Aileen MacLellan, Manoj M. Lalu
Publikováno v:
EBioMedicine, Vol 110, Iss , Pp 105473- (2024)
Externí odkaz:
https://doaj.org/article/fa0f2f9f9b5446fc87802b0fbd9ccf6b
Autor:
Adrianna Douvris, Jose L. Viñas, Shareef Akbari, Karishma Tailor, Manoj M. Lalu, Dylan Burger, Kevin D. Burns
Publikováno v:
Renal Failure, Vol 46, Iss 2 (2024)
Introduction Early diagnosis of acute kidney injury (AKI) is limited with current tools. MicroRNAs (miRNAs) are implicated in AKI pathogenesis in preclinical models, but less is known about their role in humans. We conducted a systematic review to id
Externí odkaz:
https://doaj.org/article/4262fa0e70724158837337083a378322
Autor:
Neha Sharma, Alex Chen, Leah Heinen, Ruth Liu, Dhruva J. Dwivedi, Ji Zhou, Manoj M. Lalu, Asher A. Mendelson, Braedon McDonald, Colin A. Kretz, Alison E. Fox-Robichaud, Patricia C. Liaw
Publikováno v:
Intensive Care Medicine Experimental, Vol 12, Iss 1, Pp 1-13 (2024)
Abstract Introduction Despite older adults being more vulnerable to sepsis, most preclinical research on sepsis has been conducted using young animals. This results in decreased scientific validity since age is an independent predictor of poor outcom
Externí odkaz:
https://doaj.org/article/27fd2b1cf7f24f92a98ec9a101867c38
Autor:
Manoj M. Lalu, Dawn Richards, Madison Foster, Brittany French, Angela M. Crawley, Kirsten M. Fiest, Kathryn Hendrick, Kimberly F. Macala, Asher A. Mendelson, Pat Messner, Stuart G. Nicholls, Justin Presseau, Cheryle A. Séguin, Patrick Sullivan, Bernard Thébaud, Dean A. Fergusson
Publikováno v:
Research Involvement and Engagement, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract Background Patient engagement in research is the meaningful and collaborative interaction between patients and researchers throughout the research process. Patient engagement can help to ensure patient-oriented values and perspectives are in
Externí odkaz:
https://doaj.org/article/d1346b77fe94404e9245270fe80b7977
Autor:
Radhika Vala, Manoj M. Lunagaria
Publikováno v:
Journal of Water and Climate Change, Vol 14, Iss 12, Pp 4544-4560 (2023)
A Two-Source Energy Balance (TSEB) model computes surface energy fluxes using soil surface temperature and canopy temperature. An experiment was carried out in a research farm near the agrometeorological observatory, at Anand, India to parameterize t
Externí odkaz:
https://doaj.org/article/a45797b8796f4db6b8b8c25939a9e6e5
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-20 (2023)
Abstract Background Feature selection is an essential task in single-cell RNA-seq (scRNA-seq) data analysis and can be critical for gene dimension reduction and downstream analyses, such as gene marker identification and cell type classification. Mos
Externí odkaz:
https://doaj.org/article/c31c3be8d8db4c28a21d2de841f25325
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Background Mesenchymal stromal cell-derived extracellular vesicles (MSC-EVs) are a promising cell-free therapy for acute lung injury (ALI). To date, no studies have investigated their biodistribution in ALI or discerned the timing of adminis
Externí odkaz:
https://doaj.org/article/167e6d7cf2a64263b653474a28528649
Autor:
Grace Fox, Manoj M. Lalu, Tara Sabloff, Stuart G. Nicholls, Maureen Smith, Dawn Stacey, Faris Almoli, Dean A. Fergusson
Publikováno v:
Research Involvement and Engagement, Vol 9, Iss 1, Pp 1-30 (2023)
Abstract Background Patient engagement in research refers to collaboration between researchers and patients (i.e., individuals with lived experience including informal caregivers) in developing or conducting research. Offering non-financial (e.g., co
Externí odkaz:
https://doaj.org/article/a98d96ce70ba4b2ea89e42ce4318a33e