Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Manoj Kandpal"'
Autor:
Yifan Tai, Angela Chow, Seoyoung Han, Courtney Coker, Wanchao Ma, Yifan Gu, Valeria Estrada Navarro, Manoj Kandpal, Hanina Hibshoosh, Kevin Kalinsky, Katia Manova-Todorova, Anton Safonov, Elaine M Walsh, Mark Robson, Larry Norton, Richard Baer, Taha Merghoub, Anup K Biswas, Swarnali Acharyya
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 8, Pp 1957-1980 (2024)
Abstract Acquired resistance to PARP inhibitors (PARPi) remains a treatment challenge for BRCA1/2-mutant breast cancer that drastically shortens patient survival. Although several resistance mechanisms have been identified, none have been successfull
Externí odkaz:
https://doaj.org/article/2b7acab7d8864163a88c5615d51c25ce
Autor:
Rhonda G. Kost, Rita K. Devine, Mark Fernands, Riva Gottesman, Manoj Kandpal, Robert B. MacArthur, Barbara O’Sullivan, Michelle Romanick, Andrea Ronning, Sarah Schlesinger, Jonathan N. Tobin, Roger Vaughan, Maija Neville-Williams, James G. Krueger, Barry S. Coller
Publikováno v:
Journal of Clinical and Translational Science, Vol 7 (2023)
Abstract Introduction: Clinical trials are a vital component of translational science, providing crucial information on the efficacy and safety of new interventions and forming the basis for regulatory approval and/or clinical adoption. At the same
Externí odkaz:
https://doaj.org/article/2c491e0718d2494eb07cd2435ab8b0d4
Autor:
Maria Martinez-Lage, Timothy M. Lynch, Yingtao Bi, Carolina Cocito, Gregory P. Way, Sharmistha Pal, Josephine Haller, Rachel E. Yan, Amy Ziober, Aivi Nguyen, Manoj Kandpal, Donald M. O’Rourke, Jeffrey P. Greenfield, Casey S. Greene, Ramana V. Davuluri, Nadia Dahmane
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-12 (2019)
Abstract Recent work has highlighted the tumor microenvironment as a central player in cancer. In particular, interactions between tumor and immune cells may help drive the development of brain tumors such as glioblastoma multiforme (GBM). Despite si
Externí odkaz:
https://doaj.org/article/a45cf177d9b84fa4a1138bb10a48ae14
Autor:
Justin E. Ideozu, Vittobai Rangaraj, Hiam Abdala-Valencia, Xi Zhang, Manoj Kandpal, Marc A. Sala, Ramana V. Davuluri, Hara Levy
Publikováno v:
BMC Medical Genomics, Vol 12, Iss 1, Pp 1-16 (2019)
Abstract Background In cystic fibrosis (CF), impaired immune cell responses, driven by the dysfunctional CF transmembrane conductance regulator (CFTR) gene, may determine the disease severity but clinical heterogeneity remains a major therapeutic cha
Externí odkaz:
https://doaj.org/article/b38291cc096a40c9a4af6e783d83ea7f
Autor:
Daniela Matei, Ramana V. Davuluri, Jianjun Chen, Edward J. Tanner, Anusha Chaparala, Yanrong Ji, Horacio Cardenas, Guangyuan Zhao, Manoj Kandpal, Yinu Wang, Hao Huang
Supplemental tables include gene lists related to Figure 5, additional experimental data related to Figure S3I, and primers sequence. Table S1. Numbers of spheroids were counted for each cell dilution; Table S2. List of 20 genes that exhibit a signif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4db76b7ecfc0ad59596eb28359bec1c
https://doi.org/10.1158/0008-5472.22426420.v1
https://doi.org/10.1158/0008-5472.22426420.v1
Autor:
Daniela Matei, Ramana V. Davuluri, Jianjun Chen, Edward J. Tanner, Anusha Chaparala, Yanrong Ji, Horacio Cardenas, Guangyuan Zhao, Manoj Kandpal, Yinu Wang, Hao Huang
N6-Methyladenosine (m6A) is the most abundant modification of mammalian mRNAs. RNA methylation fine tunes RNA stability and translation, altering cell fate. The fat mass- and obesity-associated protein (FTO) is an m6A demethylase with oncogenic prope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39fa8ff554637f215faedce96bb13452
https://doi.org/10.1158/0008-5472.c.6512335
https://doi.org/10.1158/0008-5472.c.6512335
Autor:
Daniela Matei, Ramana V. Davuluri, Jianjun Chen, Edward J. Tanner, Anusha Chaparala, Yanrong Ji, Horacio Cardenas, Guangyuan Zhao, Manoj Kandpal, Yinu Wang, Hao Huang
Additional experimental results supporting the main figures are included. Figure S1. Expression of key RNA methylation regulators in OC; Figure S2. Flow cytometry analysis for ALDH and CD133 in single cell suspensions derived from human ovarian tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58586bffed12f0249ddde8730d686066
https://doi.org/10.1158/0008-5472.22426426
https://doi.org/10.1158/0008-5472.22426426
Autor:
Daniela Matei, Ramana V. Davuluri, Jianjun Chen, Edward J. Tanner, Anusha Chaparala, Yanrong Ji, Horacio Cardenas, Guangyuan Zhao, Manoj Kandpal, Yinu Wang, Hao Huang
Detailed information regarding materials and methods are included in this file.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::789fb8c2e51f444d790d3c503ca8da45
https://doi.org/10.1158/0008-5472.22426423.v1
https://doi.org/10.1158/0008-5472.22426423.v1
Publikováno v:
American Journal of Transplantation. 22:532-540
Donor-derived cell-free DNA (dd-cfDNA) has been evaluated as a rejection marker in organ transplantation. This study sought to assess the utility of dd-cfDNA to diagnose graft injury in liver transplant recipients (LTR) and as a predictive biomarker
Publikováno v:
2023 IEEE Applied Sensing Conference (APSCON).