Zobrazeno 1 - 10 of 40 pro vyhledávání: '"Manoj K Bhasin"'
1
Akademický článek
Taxane chemotherapy induces stromal injury that leads to breast cancer dormancy escape.
Autor: Ramya Ganesan, Swati S Bhasin, Mojtaba Bakhtiary, Upaasana Krishnan, Nagarjuna R Cheemarla, Beena E Thomas, Manoj K Bhasin, Vikas P Sukhatme
Publikováno v: PLoS Biology, Vol 21, Iss 9, p e3002275 (2023)
A major cause of cancer recurrence following chemotherapy is cancer dormancy escape. Taxane-based chemotherapy is standard of care in breast cancer treatment aimed at killing proliferating cancer cells. Here, we demonstrate that docetaxel injures str
Externí odkaz: https://doaj.org/article/6859078ccfb9422a941de4b39a3b32a9
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3
Akademický článek
SB225002 Induces Cell Death and Cell Cycle Arrest in Acute Lymphoblastic Leukemia Cells through the Activation of GLIPR1.
Autor: Jaíra Ferreira de Vasconcellos, Angelo Brunelli Albertoni Laranjeira, Paulo C Leal, Manoj K Bhasin, Priscila Pini Zenatti, Ricardo J Nunes, Rosendo A Yunes, Alexandre E Nowill, Towia A Libermann, Luiz Fernando Zerbini, José Andrés Yunes
Publikováno v: PLoS ONE, Vol 10, Iss 8, p e0134783 (2015)
Acute Lymphoblastic Leukemia (ALL) is the most frequent childhood malignancy. In the effort to find new anti-leukemic agents, we evaluated the small drug SB225002 (N-(2-hydroxy-4-nitrophenyl)-N'-(2-bromophenyl)urea). Although initially described as a
Externí odkaz: https://doaj.org/article/e9843bd459894264bbf568c153565b4f
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4
Akademický článek
Transcriptional patterns in peritoneal tissue of encapsulating peritoneal sclerosis, a complication of chronic peritoneal dialysis.
Autor: Fabian R Reimold, Niko Braun, Zsuzsanna K Zsengellér, Isaac E Stillman, S Ananth Karumanchi, Hakan R Toka, Joerg Latus, Peter Fritz, Dagmar Biegger, Stephan Segerer, M Dominik Alscher, Manoj K Bhasin, Seth L Alper
Publikováno v: PLoS ONE, Vol 8, Iss 2, p e56389 (2013)
Encapsulating peritoneal sclerosis (EPS) is a devastating complication of peritoneal dialysis (PD), characterized by marked inflammation and severe fibrosis of the peritoneum, and associated with high morbidity and mortality. EPS can occur years afte
Externí odkaz: https://doaj.org/article/73834b03127542b58f03b8354b5f77ea
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5
Akademický článek
Relaxation response induces temporal transcriptome changes in energy metabolism, insulin secretion and inflammatory pathways.
Autor: Manoj K Bhasin, Jeffery A Dusek, Bei-Hung Chang, Marie G Joseph, John W Denninger, Gregory L Fricchione, Herbert Benson, Towia A Libermann
Publikováno v: PLoS ONE, Vol 8, Iss 5, p e62817 (2013)
The relaxation response (RR) is the counterpart of the stress response. Millennia-old practices evoking the RR include meditation, yoga and repetitive prayer. Although RR elicitation is an effective therapeutic intervention that counteracts the adver
Externí odkaz: https://doaj.org/article/e3d86dd20758475594a481511a5fbf69
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6
Akademický článek
A20 modulates lipid metabolism and energy production to promote liver regeneration.
Autor: Scott M Damrauer, Peter Studer, Cleide G da Silva, Christopher R Longo, Haley E Ramsey, Eva Csizmadia, Gautam V Shrikhande, Salvatore T Scali, Towia A Libermann, Manoj K Bhasin, Christiane Ferran
Publikováno v: PLoS ONE, Vol 6, Iss 3, p e17715 (2011)
Liver regeneration is clinically of major importance in the setting of liver injury, resection or transplantation. We have demonstrated that the NF-κB inhibitory protein A20 significantly improves recovery of liver function and mass following extend
Externí odkaz: https://doaj.org/article/1053768293f84ec89484e1c398dfb7f5
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8
Akademický článek
Functional and Transcriptomic Characterization of Peritoneal Immune-Modulation by Addition of Alanyl-Glutamine to Dialysis Fluid
Autor: Rebecca Herzog, Lilian Kuster, Julia Becker, Tobias Gluexam, Dietmar Pils, Andreas Spittler, Manoj K. Bhasin, Seth L. Alper, Andreas Vychytil, Christoph Aufricht, Klaus Kratochwill
Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Peritonitis remains a major cause of morbidity and mortality during chronic peritoneal dialysis (PD). Glucose-based PD fluids reduce immunological defenses in the peritoneal cavity. Low concentrations of peritoneal extracellular glutamine du
Externí odkaz: https://doaj.org/article/9cfa7994a28245e394ea579d9e00800f
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