Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Manohary Rajendram"'
Autor:
Melanie R. Silvis, Manohary Rajendram, Handuo Shi, Hendrik Osadnik, Andrew N. Gray, Spencer Cesar, Jason M. Peters, Cameron C. Hearne, Parth Kumar, Horia Todor, Kerwyn Casey Huang, Carol A. Gross
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
Essential genes make up only ∼5 to 10% of the genetic complement in most organisms but occupy much of their protein synthesis and account for almost all antibiotic targets. Despite the importance of essential genes, their intractability has, until
Externí odkaz:
https://doaj.org/article/ac0ea87fcbd444e6a5571025f19f94b5
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102348- (2021)
Summary: Fixation facilitates imaging of subcellular localization and cell morphology, yet it remains unknown how fixation affects cellular dimensions and intracellular fluorescence patterns, particularly during long-term storage. Here, we characteri
Externí odkaz:
https://doaj.org/article/a1d44f88dbbf4adbb298e54d0da0a6f0
Autor:
Esha Atolia, Spencer Cesar, Heidi A. Arjes, Manohary Rajendram, Handuo Shi, Benjamin D. Knapp, Somya Khare, Andrés Aranda-Díaz, Richard E. Lenski, Kerwyn Casey Huang
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT Bacterial growth under nutrient-rich and starvation conditions is intrinsically tied to the environmental history and physiological state of the population. While high-throughput technologies have enabled rapid analyses of mutant libraries,
Externí odkaz:
https://doaj.org/article/7ba8cdbef49643fca248f598ea6e92fd
Autor:
George K. Auer, Piercen M. Oliver, Manohary Rajendram, Ti-Yu Lin, Qing Yao, Grant J. Jensen, Douglas B. Weibel
Publikováno v:
mBio, Vol 10, Iss 5 (2019)
ABSTRACT Swarmer cells of the Gram-negative uropathogenic bacteria Proteus mirabilis and Vibrio parahaemolyticus become long (>10 to 100 μm) and multinucleate during their growth and motility on polymer surfaces. We demonstrated that the increasing
Externí odkaz:
https://doaj.org/article/e6e11d42cad94fd08e6c6329f9bfb407
Autor:
Parth Kumar, Carol A. Gross, Hendrik Osadnik, Spencer Cesar, Melanie R. Silvis, Kerwyn Casey Huang, Cameron C. Hearne, Handuo Shi, Horia Todor, Jason M. Peters, Andrew N. Gray, Manohary Rajendram
Publikováno v:
mBio
mBio, Vol 12, Iss 5 (2021)
mBio, Vol 12, Iss 5 (2021)
CRISPR interference (CRISPRi) has facilitated the study of essential genes in diverse organisms using both high-throughput and targeted approaches. Despite the promise of this technique, no comprehensive arrayed CRISPRi library targeting essential ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb7411aca698d520e96b5ae041d7d83f
https://pubmed.ncbi.nlm.nih.gov/34634934
https://pubmed.ncbi.nlm.nih.gov/34634934
Autor:
Karina B. Xavier, Andrés Aranda-Díaz, Nate Cira, Kerwyn Casey Huang, Benjamin H. Good, Feiqiao Brian Yu, Kimberly S. Vasquez, Gavin Sherlock, Lisa Willis, Norma Neff, Justin L. Sonnenburg, Miguel F. Pedro, Steven K. Higginbottom, Manohary Rajendram, Stephen R. Quake, Katharine M. Ng
Publikováno v:
Cell Host Microbe
Summary Due to limitations on high-resolution strain tracking, selection dynamics during gut microbiota colonization and transmission between hosts remain mostly mysterious. Here, we introduced hundreds of barcoded Escherichia coli strains into germ-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878e8db9e80b0ba1592b71c1c116638c
https://europepmc.org/articles/PMC8445907/
https://europepmc.org/articles/PMC8445907/
Autor:
Douglas B. Weibel, Manohary Rajendram, Brandon M. Hoover, Heidi Y. Shi, Ming Zhang, Nitin Mahajan, Kiyoshi Kawasaki
Publikováno v:
The FASEB Journal. 33:6354-6364
A central question in cell biology is how cells respond to stress signals and biochemically regulate apoptosis. One critical pathway involves the change of mitochondrial function and release of cytochrome c to initiate apoptosis. In response to apopt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0daf0174781c1571c0e070105e053bd
https://doi.org/10.1096/fj.201802182r
https://doi.org/10.1096/fj.201802182r
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102348-(2021)
iScience
iScience
Summary Fixation facilitates imaging of subcellular localization and cell morphology, yet it remains unknown how fixation affects cellular dimensions and intracellular fluorescence patterns, particularly during long-term storage. Here, we characteriz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::766f2d7714695884139ec08030f97474
http://www.sciencedirect.com/science/article/pii/S2589004221003163
http://www.sciencedirect.com/science/article/pii/S2589004221003163
Autor:
Spencer Cesar, Manohary Rajendram, Benjamin D. Knapp, Esha Atolia, Handuo Shi, Heidi A. Arjes, Somya Khare, Richard E. Lenski, Kerwyn Casey Huang, Andrés Aranda-Díaz
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
mBio
mBio
How starved bacteria adapt and multiply under replete nutrient conditions is intimately linked to their history of previous growth, their physiological state, and the surrounding environment. While automated equipment has enabled high-throughput grow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7305514de6d73eb824ac80452ea225ad
https://doi.org/10.1101/2020.06.16.156182
https://doi.org/10.1101/2020.06.16.156182
Autor:
Qing Yao, Manohary Rajendram, Douglas B. Weibel, George K. Auer, Ti-Yu Lin, Grant J. Jensen, Piercen M. Oliver
Publikováno v:
mBio, Vol 10, Iss 5 (2019)
mBio
mBio, Vol 10, Iss 5, p e00210-19 (2019)
mBio
mBio, Vol 10, Iss 5, p e00210-19 (2019)
Proteus mirabilis and Vibrio parahaemolyticus are bacteria that infect humans. To adapt to environmental changes, these bacteria alter their cell morphology and move collectively to access new sources of nutrients in a process referred to as “swarm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::267f1593c7dc8cda60ec02d7263ccd53
https://journals.asm.org/doi/10.1128/mBio.00210-19
https://journals.asm.org/doi/10.1128/mBio.00210-19