Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Manohar, Pradhan"'
Autor:
Bilal Unal, Omer Faruk Kuzu, Yang Jin, Daniel Osorio, Wanja Kildal, Manohar Pradhan, Sonia H. Y. Kung, Htoo Zarni Oo, Mads Daugaard, Mikkel Vendelbo, John B. Patterson, Martin Kristian Thomsen, Marieke Lydia Kuijjer, Fahri Saatcioglu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Unfolded protein response (UPR) is a central stress response pathway that is hijacked by tumor cells for their survival. Here, we find that IRE1α signaling, one of the canonical UPR arms, is increased in prostate cancer (PCa) patient tumors
Externí odkaz:
https://doaj.org/article/874eae97dbf2430b9b55fe9cb39598cb
Autor:
Wanja Kildal, Karolina Cyll, Joakim Kalsnes, Rakibul Islam, Frida M. Julbø, Manohar Pradhan, Elin Ersvær, Neil Shepherd, Ljiljana Vlatkovic, Xavier Tekpli, Øystein Garred, Gunnar B. Kristensen, Hanne A. Askautrud, Tarjei S. Hveem, Håvard E. Danielsen, Tone F. Bathen, Elin Borgen, Anne-Lise Børresen-Dale, Olav Engebråten, Britt Fritzman, Olaf Johan Hartman-Johnsen, Jürgen Geisler, Gry Aarum Geitvik, Solveig Hofvind, Rolf Kåresen, Anita Langerød, Ole Christian Lingjærde, Gunhild M. Mælandsmo, Bjørn Naume, Hege G. Russnes, Kristine Kleivi Sahlberg, Torill Sauer, Helle Kristine Skjerven, Ellen Schlichting, Therese Sørlie
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e32529- (2024)
We aimed to develop deep learning (DL) models to detect protein expression in immunohistochemically (IHC) stained tissue-sections, and to compare their accuracy and performance with manually scored clinically relevant proteins in common cancer types.
Externí odkaz:
https://doaj.org/article/e0dc5fe8cfec49769db7555ff4402d86
Publikováno v:
Journal of Gandaki Medical College, Vol 15, Iss 2, Pp 128-132 (2022)
Introduction: Hypovolemic shock is diagnosed by the signs of hemodynamic instability and when the source of volume loss is obvious. Among various types, hypovolemic shock is the most common which results either from the loss of blood from hemorrhage
Externí odkaz:
https://doaj.org/article/33980a4a02e54b0d9c876640f61267ba
Publikováno v:
International Journal of Emergency Medicine, Vol 15, Iss 1, Pp 1-10 (2022)
Abstract Background Emergency medical care, including prehospital treatment, forms an important component of any healthcare system. Like most low-middle-income countries, Nepal has an emergency medical system that can be described as underdeveloped.
Externí odkaz:
https://doaj.org/article/79c8457bb19f4212b95595b9fe2e6787
Publikováno v:
Journal of Nepal Medical Association, Vol 61, Iss 258 (2023)
Introduction: Road traffic accidents are a public health problem and have emerged as the leading cause of mortality and morbidity. Head is the most commonly affected site of road traffic accidents. The aim of this study was to find out the prevalence
Externí odkaz:
https://doaj.org/article/0416e60d3a6c4ef1bb1ecfd9450098ab
Autor:
Anjani Kumar Jha, Pradeep Neupane, Manohar Pradhan, Krishna Sagar Sharma, Sadina Shrestha, Padma Raj Sigdel, Sigbjørn Smeland, Øyvind S. Bruland
Publikováno v:
Journal of Global Oncology, Vol 5, Pp 1-10 (2019)
PURPOSE: To our knowledge, we conducted the first prospective oncologic clinical trial in Nepal aimed at providing state-of-the-art chemotherapy to patients with Ewing sarcoma. The efficacy of external-beam radiotherapy (RT) as the sole local treatme
Externí odkaz:
https://doaj.org/article/b2f2f16c34a6488a9bbcef9d8baebe74
Publikováno v:
Journal of Chitwan Medical College. 12:77-81
Background: Introduction to Clinical Medicine (ICM) is a relatively new and innovative approach for teaching medicine. ICM engages medical students in their understanding of the disease process from clinical feature to diagnosis, studying abnormaliti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::139194432b7f90278d2004beee3eaac1
https://doi.org/10.54530/jcmc.1217
https://doi.org/10.54530/jcmc.1217
Publikováno v:
Journal of College of Medical Sciences-Nepal. 18:304-310
Introduction: Poisoning is an acute medical emergency. Organophosphorus (OP) poison, being easily available and relatively cheaper, is mostly used by people for suicide. It is a major health problem worldwide also a major cause of suicide in Nepal. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abc2b5264c2af0df578c8419572be71b
https://doi.org/10.3126/jcmsn.v18i3.48994
https://doi.org/10.3126/jcmsn.v18i3.48994
Autor:
Manohar Pradhan
Publikováno v:
Journal of College of Medical Sciences-Nepal, Vol 13, Iss 3, Pp 323-326 (2017)
Background & Objectives:Students of colleges may be vulnerable to consume tobacco, alcohol and psychoactive drugs due to various factors. This study was conducted with objectives of determining the prevalence of smoking, alcohol and psychoactive drug
Externí odkaz:
https://doaj.org/article/a8dca5ddce9b4097bfb9d94b32fd1c65
Autor:
Maria P. Silva, João D. Barros-Silva, Elin Ersvær, Wanja Kildal, Tarjei Sveinsgjerd Hveem, Manohar Pradhan, Joana Vieira, Manuel R. Teixeira, Håvard E. Danielsen
Publikováno v:
Translational Oncology, Vol 9, Iss 6, Pp 575-582 (2016)
Overtreatment is a major concern in men diagnosed with prostate cancer. The aim of this study was to evaluate the combined prognostic role of three frequent molecular alterations in prostate cancer, namely relative 8q gain, ERG overexpression, and lo
Externí odkaz:
https://doaj.org/article/11ff607597444a0e898f195f3e27f591