Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Manogaran, Elumalai"'
Publikováno v:
Beni-Suef University Journal of Basic and Applied Sciences, Vol 11, Iss 1, Pp 1-13 (2022)
Abstract Background Vorinostat is a histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) with anticancer properties. However, it is plagued by low water solubility, low permeability (BCS class IV drug), and suboptimal pharmacokinetics
Externí odkaz:
https://doaj.org/article/d379294370be4339b9a8511b8fc77045
Autor:
Mudduluru Niranjan Babu, Karthikeyan Elumalai, Sivaneswari Srinivasan, Kalpana Eluri, Manogaran Elumalai, Srinivasan Sivannan
Publikováno v:
Carbon Resources Conversion, Vol 2, Iss 3, Pp 191-197 (2019)
A novel Acetazolamide condensed 1, 4-dihydropyridines was set up by treating of N-(5-acetamido-1, 3, 4-thiadiazol-2-ylsulfonyl)-3-oxobutanamide with an aryl aldehyde and 25–30% alkali with sight amount of barium nitrate as a catalyst. Confirmation
Externí odkaz:
https://doaj.org/article/a4f217828c75430aa0c3bee53d51cae2
Autor:
Karthikeyan Elumalai, Mohammed Ashraf Ali, Sivaneswari Srinivasan, Manogaran Elumalai, Kalpana Eluri
Publikováno v:
Journal of Taibah University for Science, Vol 11, Iss 1, Pp 46-56 (2017)
The purpose of the study was to synthesize potent antimicrobial and cytotoxic agents by condensing sulphanilamide with 1,2,3,4-tetrahydropyrimidines. A new series of novel sulphanilamide condensed 1,2,3,4-tetrahydropyrimidines was prepared by reactin
Externí odkaz:
https://doaj.org/article/d16023d9f4624816aafccaceb7219e3d
Autor:
Karthikeyan Elumalai, Manogaran Elumalai, Kalpana Eluri, Sivaneswari Srinivasan, Mohamed Ashraf Ali, Basu Venkateswara Reddy, Sarada Prasad Sarangi
Publikováno v:
Bulletin of Faculty of Pharmacy Cairo University, Vol 54, Iss 1, Pp 77-86 (2016)
A new series of some novel isoniazid condensed 1,4-dihydropyridines was prepared by reaction of N-(3-oxobutanoyl) isonicotinohydrazide with aryl aldehyde and 25–30% ammonia solution in the presence of catalytic amount of barium nitrate as an effici
Externí odkaz:
https://doaj.org/article/c6d598a1e8fd46ceaaeaa3ae6485198e
Autor:
Manogaran Elumalai, Habibur Rahman Shiek Abdul Kadhar Mohamed Ebrahim, Hariprasad Ranganathan, Sivaselvakumar Muthusamy, Karthik Siram, Karthik Sridhar, Telny Thomas Chungath
Publikováno v:
Turk J Pharm Sci
OBJECTIVES: The present study aimed to develop and validate a discriminative dissolution method for tetrahydrocurcumin (THC), a Biopharmaceutical Classification System class II drug, by a simple ultraviolet (UV) spectrophotometric analysis. The final
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bca1f4b5e90cc1531284bc882741b00
https://doi.org/10.4274/tjps.galenos.2021.91145
https://doi.org/10.4274/tjps.galenos.2021.91145
Publikováno v:
Current Drug Therapy. 16:430-438
Background: Tetrahydrocurcumin is a hydrogenated active metabolite of curcumin that exhibits similar pharmacological effects to curcumin. However, its hydrophobic nature has limited its aqueous solubility and bioavailability. By incorporating the tet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d023d275b5916e0c1c5f0b5cb225813
https://doi.org/10.2174/1574885516666211210153741
https://doi.org/10.2174/1574885516666211210153741
Autor:
Karthikeyan Elumalai, Mohammed Ashraf Ali, Manogaran Elumalai, Kalpana Eluri, Sivaneswari Srinivasan
Publikováno v:
Biotechnology Reports, Vol 5, Iss C, Pp 1-6 (2015)
A new series of some novel pyrazinamide condensed 1,2,3,4-tetrahydropyrimidines was prepared by reacting of N-(3-oxobutanoyl)pyrazine-2-carboxamide with urea/thiourea and appropriate aldehyde in the presence of catalytic amount of laboratory made p-t
Externí odkaz:
https://doaj.org/article/13e06f9aff684ad3a45200c86c45891d
Publikováno v:
Research Journal of Pharmacy and Technology. :3553-3558
The drug of choice in the treatment of postmenopausal osteoporosis is alendronate. Antidepressive agents are currently used in combination with alendronate to protect against depression and may affect the condition of osteoporosis. The aim is to stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e294503475bc5f6dd1aa2ab447ea668
https://doi.org/10.52711/0974-360x.2021.00615
https://doi.org/10.52711/0974-360x.2021.00615
Autor:
Karthikeyan Elumalai, Mohammed Ashraf Ali, Manogaran Elumalai, Kalpana Eluri, Sivaneswari Srinivasan, Sujit Kumar Mohanty
Publikováno v:
Beni-Suef University Journal of Basic and Applied Sciences, Vol 3, Iss 1, Pp 24-31 (2014)
A new series of some novel acetazolamide cyclocondensed 1,2,3,4-tetrahydropyrimidines was prepared by reacting of N-{[5-(acetylamino)-1,3,4-thiadiazol-2-yl]sulfonyl}-3-oxobutanamide with urea/thiourea and appropriate aldehyde in the presence of catal
Externí odkaz:
https://doaj.org/article/34d5aaade0f4436fa2ace276703c285b
Autor:
Palanirajan Vijayaraj Kumar, Marwan Abdelmahmoud Abdelkarim Maki, Manogaran Elumalai, Omer Bayazeid
Publikováno v:
Current Drug Discovery Technologies. 18:451-456
Aims:: To utilize in silico-based approach for investigating the ability of PEGylated rapamycin as a competitive inhibitor to Galectin-3 for curing various diseases or that may provide an attractive strategy for treatment of a wide variety of tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::787b962486358b8bc9182e3dc53044ba
https://doi.org/10.2174/1570163817666200122162042
https://doi.org/10.2174/1570163817666200122162042