Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Manoela V Fogaça"'
Autor:
Aviva Breuer, Christeene G Haj, Manoela V Fogaça, Felipe V Gomes, Nicole Rodrigues Silva, João Francisco Pedrazzi, Elaine A Del Bel, Jaime C Hallak, José A Crippa, Antonio W Zuardi, Raphael Mechoulam, Francisco S Guimarães
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0162087 (2016)
[This corrects the article DOI: 10.1371/journal.pone.0158779.].
Externí odkaz:
https://doaj.org/article/a6e436726417429786cd77082b260ba9
Autor:
Aviva Breuer, Christeene G Haj, Manoela V Fogaça, Felipe V Gomes, Nicole Rodrigues Silva, João Francisco Pedrazzi, Elaine A Del Bel, Jaime C Hallak, José A Crippa, Antonio W Zuardi, Raphael Mechoulam, Francisco S Guimarães
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158779 (2016)
Cannabidiol (CBD) is a major Cannabis sativa constituent, which does not cause the typical marijuana psychoactivity. However, it has been shown to be active in a numerous pharmacological assays, including mice tests for anxiety, obsessive-compulsive
Externí odkaz:
https://doaj.org/article/22e3c2f661ed44f687ffb78e00bffb58
Autor:
Chan Li, Jiping Zhang, Hanhe Liu, Huijie Yuan, Jianxin Cai, Manoela V. Fogaça, Yuan-Wei Zhang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 165, Iss , Pp 115137- (2023)
Depression is a multifactorial syndrome with a variety of underlying pathological mechanisms. While ketamine, an N-methyl-D-aspartate receptor (NMDAR) antagonist, exhibits a rapid antidepressant action in the central never system (CNS), the potential
Externí odkaz:
https://doaj.org/article/f01489682cd54e5788972de7ec16e48c
Autor:
Débora A. E. Colodete, Nicole R. Silva, João Francisco C. Pedrazzi, Manoela V. Fogaça, Isadora Cortez, Elaine A. Del-Bel, Aviva Breuer, Raphael Mechoulam, Felipe V. Gomes, Francisco S. Guimarães
Publikováno v:
Behavioural Pharmacology. 34:213-224
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d032733165c3161673a0ba0bd55d51a
https://doi.org/10.1097/fbp.0000000000000727
https://doi.org/10.1097/fbp.0000000000000727
Autor:
Gisele A. Locachevic, Morgana K. B. Prado, Karina F. Zoccal, Priscilla A. T. Pereira, Carlos A. Sorgi, Mariza Bortolanza, Ana Paula F. Peti, Manoela V. Fogaça, Francisco S. Guimarães, Elaine Del Bel, Lúcia H. Faccioli
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 13 (2019)
Depression is a mental illness with a complex and multifactorial etiology, which has been associated with stress and inflammation. Infections, autoimmune diseases, envenomation, and trauma induce an inflammatory response that is characterized by incr
Externí odkaz:
https://doaj.org/article/65ddae0a20e146afb71abc13b16a00dc
Publikováno v:
Neuropsychopharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22c5611491c6156f9fa83336f0d65d32
https://doi.org/10.1038/s41386-023-01583-7
https://doi.org/10.1038/s41386-023-01583-7
Publikováno v:
Molecular psychiatry
Major depressive disorder (MDD) is associated with alterations of GABAergic interneurons, notably somatostatin (Sst) as well as parvalbumin (Pvalb), in cortical brain areas. In addition, the antidepressant effects of rapid-acting drugs are thought to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3dc1af9d2ca479498deb3ba242a9057
http://europepmc.org/articles/PMC8052382
http://europepmc.org/articles/PMC8052382
Autor:
Catharine H. Duman, Manoela V. Fogaça, Kenichi Fukumoto, Shigeyuki Chaki, Ronald S. Duman, Xiaoyuan Li, Rong-Jian Liu
Publikováno v:
Neuropsychopharmacology. 45:1725-1734
We previously reported that the serotonergic system is important for the antidepressant-like effects of ketamine, a non-competitive N-methyl-D-aspartate receptor antagonist, which produces rapid and long-lasting antidepressant effects in patients wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4bd7611f779fc3cc60b308750bc8587
https://doi.org/10.1038/s41386-020-0705-0
https://doi.org/10.1038/s41386-020-0705-0
Autor:
Catharine H. Duman, Tina C. Franklin, Kenichi Fukumoto, Ronald S. Duman, Ottavio V. Vitolo, Manoela V. Fogaça, Rong-Jian Liu
Publikováno v:
Neuropsychopharmacology
Currently available antidepressants have a delayed onset and limited efficacy, highlighting the need for new, rapid and more efficacious agents. Ketamine, an NMDA receptor antagonist, has emerged as a new rapid-acting antidepressant, effective even i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e449fc2728124b7e6fa5063da1b9da17
https://doi.org/10.1038/s41386-019-0501-x
https://doi.org/10.1038/s41386-019-0501-x
Autor:
Manoela V. Fogaça, Rong-Jian Liu, Xiaoyuan Li, Taro Kato, Ronald S. Duman, Catharine H. Duman, Kenichi Fukumoto
Publikováno v:
Proceedings of the National Academy of Sciences. 116:297-302
Ketamine, a noncompetitive N-methyl-d-aspartate (NMDA) receptor antagonist, produces rapid and long-lasting antidepressant effects in major depressive disorder (MDD) patients. (2R,6R)-Hydroxynorketamine [(2R,6R)-HNK], a metabolite of ketamine, is rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc2989ec18e63caf43e9398ed870cff3
https://doi.org/10.1073/pnas.1814709116
https://doi.org/10.1073/pnas.1814709116