Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Manoel Jorge Nobre"'
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Fear and anxiety are generally assessed as responses of prey to high or low levels of threatening environments, fear-conditioned or unconditioned stimuli, or the intensity and distance between predator and prey. Depending on whether a threat is close
Externí odkaz:
https://doaj.org/article/a533128069b542f1ae9f53f5ea2b1bfe
Publikováno v:
Neurochemical Research. 46:1686-1700
Like other drugs, ketamine is abused due to its ability to act as a positive reinforcer in the control of behavior, just as natural reinforcers do. Besides, through Pavlovian conditioning, tolerance to drug effects can become conditioned to specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2909f6cf4ea7cefd9d186bb0f7160b4e
https://doi.org/10.1007/s11064-021-03300-6
https://doi.org/10.1007/s11064-021-03300-6
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Emotional disturbances emerge following alcohol withdrawal. The anxiolytic effect of alcohol may be one important motivation for its consumption in conditions where alcohol intake is anxiety reducing. Besides, early alcohol experience will predict fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f75bdee80d6c9fe93bf1e4bea52d8717
Autor:
Manoel Jorge Nobre
Publikováno v:
International Journal of Developmental Neuroscience. 55:15-27
Exposure to stress and prolonged exposure to alcohol leads to neuronal damages in several brain regions, being the medial prefrontal cortex (mPFC) one of the most affected. These changes presumably reduce the ability of the organism to cope with thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::474b7062a1304d234cba3eeaa25d8afa
https://doi.org/10.1016/j.ijdevneu.2016.09.003
https://doi.org/10.1016/j.ijdevneu.2016.09.003
Publikováno v:
Hormones and Behavior. 84:84-96
Hormones highly influence female behaviors. However, research on this topic has not usually considered the variable hormonal status. The prelimbic cortex (PrL) is commonly engaged in fear learning. Connections from and to this region are known to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a60afd7887f8b1e7cdafb8eb07453ef
https://doi.org/10.1016/j.yhbeh.2016.05.017
https://doi.org/10.1016/j.yhbeh.2016.05.017
Publikováno v:
Neurotoxicology. 69
Ketamine (KET) is a non-competitive N-Methyl-d-aspartate (NMDA) receptors antagonist that intensifies sensory experiences, prompts hallucinations and delusions, exacerbates previously installed psychosis and disrupts physiological evoked potentials (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c453b28e951a863a677b4d28b9adae
https://pubmed.ncbi.nlm.nih.gov/30170016
https://pubmed.ncbi.nlm.nih.gov/30170016
Publikováno v:
Neuroscience. 392
Auditory-evoked potentials (AEPs) can be modified by associative learning, where the appearance of learned compensatory responses (CCRs) may result in the emergence of drug withdrawal symptoms and relapse. Although CCRs’ influence on later attentiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e5fb0907dcbe84aa627cfaaa2c2e98b
https://pubmed.ncbi.nlm.nih.gov/30267831
https://pubmed.ncbi.nlm.nih.gov/30267831
Autor:
Manoel Jorge Nobre, Gabriel Shimizu Bassi, Alexandre Kanashiro, Francele M. Santin, Norberto Cysne Coimbra, Glória Emília Petto de Souza
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 110:359-369
The fact that there is a complex and bidirectional communication between the immune and nervous systems has been well demonstrated. Lipopolysaccharide (LPS), a component of gram-negative bacteria, is widely used to systematically stimulate the immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b1336e0fd3d493dc01c8f152e149240
https://doi.org/10.1111/j.1742-7843.2011.00824.x
https://doi.org/10.1111/j.1742-7843.2011.00824.x
Publikováno v:
Neuroscience. 171:1152-1163
The inferior colliculus (IC) is primarily involved in the processing of acoustic stimuli, being in a position to send auditory information to motor centers that participate in behaviors such as prey catching and predators' avoidance. The role of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3137e5e2254e2047c3f67b7dae79c2c7
https://doi.org/10.1016/j.neuroscience.2010.10.011
https://doi.org/10.1016/j.neuroscience.2010.10.011
Publikováno v:
Neuroscience. 161:707-717
Rats segregated according to low (LA) or high (HA) anxiety levels have been used as an important tool in the study of fear and anxiety. Since the efficacy of an anxiolytic compound is a function of the animal's basal anxiety level, it is possible tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65210f76a4a482b890008b62ddd53c4f
https://doi.org/10.1016/j.neuroscience.2009.03.073
https://doi.org/10.1016/j.neuroscience.2009.03.073