Zobrazeno 1 - 10
of 355
pro vyhledávání: '"Manoalide"'
Autor:
Yinyun Ni, Jiaye Liu, Lingyan Zeng, Ying Yang, Lei Liu, Menglin Yao, Li Chai, Lu Zhang, Yi Li, Li Zhang, Weimin Li
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2023)
Background: Manoalide (MA), a proven natural inhibitor of PLA2 has anticancer effects, but its potential application and mechanism as an anticancer drug to promote EGFR-TKI sensitivity in lung cancer cells have not been studied.Methods: KRAS-mutated
Externí odkaz:
https://doaj.org/article/13c9a0e86b254d1695e37f092c8a4c20
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The activation of NLRP3 inflammasome leads to cell pyroptosis and inflammatory cytokines secretion and gets involved in the development of many diseases, such as neuroinflammation and metabolic syndrome, but the drugs targeting NLRP3 are not clinical
Externí odkaz:
https://doaj.org/article/286174661fb748a2a7d25295b86bf8b6
Publikováno v:
Environmental Health Perspectives, 1996 Jan 01. 104(1), 52-58.
Externí odkaz:
https://www.jstor.org/stable/3432760
Akademický článek
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Publikováno v:
Immunopharmacology and Immunotoxicology. 43:799-805
Many people are troubled by allergic inflammation including ocular allergic diseases, anaphylaxis, allergic rhinitis, atopic dermatitis, and eczema. Consequently, finding medications for use in allergic inflammation therapy is crucial in human health
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6886f9b5446e90e02ff537bdbeb037cc
https://doi.org/10.1080/08923973.2021.1988101
https://doi.org/10.1080/08923973.2021.1988101
Publikováno v:
Journal of Natural Products. 84:1676-1680
Oshimalides A (1) and B (2) were isolated from a Luffariella sp. marine sponge. The absolute configurations of the stereogenic centers in the cyclohexenone ring were determined by the modified Mosher's analysis of the reduction product. The absolute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::340dbd19d73dcc62c468b0fd921310f6
https://doi.org/10.1021/acs.jnatprod.1c00320
https://doi.org/10.1021/acs.jnatprod.1c00320
Publikováno v:
Journal of Natural Products. 84:61-70
Thirteen new linear terpenes, including 11 rare acyclic manoalide derivatives (1-11), one polyprenylphenol derivative (12), and one polyprenylbenzaldehyde derivative (13), together with three known compounds (14-16) were isolated from the sponge Luff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4da5251dcdc0b49d4f26da80e8f5d4e9
https://doi.org/10.1021/acs.jnatprod.0c01026
https://doi.org/10.1021/acs.jnatprod.0c01026
Autor:
Christian Melander, Justin J. Richards, Richele Thompson, Ashley T. Tucker, Sean D. Stowe, John Cavanagh
Publikováno v:
Marine Drugs, Vol 9, Iss 10, Pp 2010-2035 (2011)
Bacterial biofilms are surface-attached communities of microorganisms that are protected by an extracellular matrix of biomolecules. In the biofilm state, bacteria are significantly more resistant to external assault, including attack by antibiotics.
Externí odkaz:
https://doaj.org/article/5d4f5dfd650f438b942f6e5afd4fdde2
Publikováno v:
Marine Drugs, Vol 8, Iss 1, Pp 190-199 (2010)
The viviparous Great Barrier Reef sponge Luffariella variabilis (Poléjaeff 1884) contains a range of secondary metabolites, including manoalide (1) and manoalide monoacetate (3). ESI (+) FTICR-MS accurate mass determination has, for the first time,
Externí odkaz:
https://doaj.org/article/f706a3debab24a189e48f0f10fd76f3c
Akademický článek
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