Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Mano Ram Maurya"'
Publikováno v:
Frontiers in Physiology, Vol 4 (2013)
Originally discovered as regulators of developmental timing in C. elegans, microRNAs (miRNAs) have emerged as modulators of nearly every cellular process, from normal development to pathogenesis. With the advent of whole genome libraries of miRNA mim
Externí odkaz:
https://doaj.org/article/b7cbb907c3a440ca85d8905315b67c02
Identification of crosstalk between phosphoprotein signaling pathways in RAW 264.7 macrophage cells.
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 1, p e1000654 (2010)
Signaling pathways mediate the effect of external stimuli on gene expression in cells. The signaling proteins in these pathways interact with each other and their phosphorylation levels often serve as indicators for the activity of signaling pathways
Externí odkaz:
https://doaj.org/article/a555afc1498c4e33b7818b23c13154c9
Autor:
Shankar Subramaniam, Rubesh Raja, Sana Khanum, Lina Aboulmouna, Mano Ram Maurya, Ananth Grama, Doraiswami Ramkrishna, Shakti Gupta
Publikováno v:
Current Opinion in Chemical Engineering. 30:120-127
Regulation of metabolism in mammalian cells is achieved through a complex interplay between cellular signaling, metabolic reactions, and transcriptional changes. The modeling of metabolic fluxes in a cell requires the knowledge of all these mechanism
Autor:
Shankar Subramaniam, John Y.-J. Shyy, Mano Ram Maurya, Zhen Chen, Shakti Gupta, Shu Chien, Julie Yi-Shuan Li, Nassim E. Ajami
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 4
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
The two main blood flow patterns, namely, pulsatile shear (PS) prevalent in straight segments of arteries and oscillatory shear (OS) observed at branch points, are associated with atheroprotective (healthy) and atheroprone (unhealthy) vascular phenot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dabf6659446a11fdd672b7866554b03
https://escholarship.org/uc/item/1t36r845
https://escholarship.org/uc/item/1t36r845
Autor:
Mano Ram Maurya, Manish Sud, Eoin Fahy, Coakley K, Kumari Sonal Choudhary, Shankar Subramaniam
With the advent of high throughput mass spectrometric methods, metabolomics has emerged as an essential area of research in biomedicine with the potential to provide deep biological insights into normal and diseased functions in physiology. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fddb7a92aad83de4baf175021311fb5
https://doi.org/10.1101/2020.11.20.391912
https://doi.org/10.1101/2020.11.20.391912
Autor:
Bing He, Shankar Subraminiam, Yu Liu, Cameron Lassiter, Hui Li, Mano Ram Maurya, Paula Benny, Lana X. Garmire
Preeclampsia is a pregnancy specific syndrome characterized by hypertension and proteinuria after 20 weeks of gestation. To reveal the relationship between lipids and preeclampsia, we conduct lipidomic profiling of maternal serums of 44 severe preecl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43bfff4febf3d4250a6ce353eea3d4c8
https://doi.org/10.1101/2020.07.05.20145292
https://doi.org/10.1101/2020.07.05.20145292
Autor:
Shankar Subramaniam, Ke Wei, Mark Mercola, Pilar Ruiz-Lozano, Marta Diez-Cuñado, Mano Ram Maurya, Paul J. Bushway, Ranjan J. Perera
Publikováno v:
Cell reports
SUMMARY Understanding the mechanisms that control human cardiomyocyte proliferation might be applicable to regenerative medicine. We screened a whole genome collection of human miRNAs, identifying 96 to be capable of increasing proliferation (DNA syn
Autor:
Hsien Da Huang, Hsi-Yuan Huang, Shankar Subramaniam, Ting Lei, Yong Jiang Xu, Jiao Zhang, Mano Ram Maurya, Jie Li, Liang Bai, Jian Kang, Marcy Martin, Shakti Gupta, John Y.-J. Shyy, Guangjin Zhou, Zhao Li, Jin Zhang, Mohit Jain, Mukesh K. Jain, Ming He, Panjamaporn Sangwung
Publikováno v:
Circulation, vol 136, iss 14
Background: Atherosclerosis is a multifaceted inflammatory disease involving cells in the vascular wall (eg, endothelial cells [ECs]), as well as circulating and resident immunogenic cells (eg, monocytes/macrophages). Acting as a ligand for liver X r
Autor:
Nassim E. Ajami, Phu Nguyen, Shankar Subramaniam, John Y.-J. Shyy, Mano Ram Maurya, Shakti Gupta, Shu Chien, Julie Yi-Shuan Li, Zhen Chen
Publikováno v:
Proceedings of the National Academy of Sciences. 114:10990-10995
Blood flow and vascular shear stress patterns play a significant role in inducing and modulating physiological responses of endothelial cells (ECs). Pulsatile shear (PS) is associated with an atheroprotective endothelial phenotype, while oscillatory
Publikováno v:
HISB
Reconstruction of biological and biochemical networks is a crucial step in extracting knowledge and causal information from large biological data sets. This task is particularly challenging when dealing with time-series data from dynamic networks. We