Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Mannil Thomas Abraham"'
Autor:
Sivaraj Raman, Asrul Akmal Shafie, Bee Ying Tan, Mannil Thomas Abraham, Shim Chen Kiong, Sok Ching Cheong
Publikováno v:
Healthcare, Vol 11, Iss 8, p 1198 (2023)
A lack of guidance on economic evaluations for oral cancer screening programs forms a challenge for policymakers and researchers to fill the knowledge gap on their cost-effectiveness. This systematic review thus aims to compare the outcomes and desig
Externí odkaz:
https://doaj.org/article/65aa26227fc043bbb6831d70be50a12e
Autor:
Chuan Wang, Nur Syafinaz Zainal, San Jiun Chai, James Dickie, Chai Phei Gan, Natasha Zulaziz, Bryan Kit Weng Lye, Ruhcha V. Sutavani, Christian H. Ottensmeier, Emma V. King, Mannil Thomas Abraham, Siti Mazlipah binti Ismail, Shin Hin Lau, Thomas George Kallarakkal, Kein Seong Mun, Rosnah binti Zain, Zainal Ariff Abdul Rahman, Gareth J. Thomas, Sok Ching Cheong, Natalia Savelyeva, Kue Peng Lim
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
HPV-independent head and neck squamous cell carcinoma (HNSCC) is a common cancer globally. The overall response rate to anti-PD1 checkpoint inhibitors (CPIs) in HNSCC is ~16%. One major factor influencing the effectiveness of CPI is the level of tumo
Externí odkaz:
https://doaj.org/article/4e3b57700cad491b8b3126170d014e2b
Autor:
Sivaraj Raman, Asrul Akmal Shafie, Mannil Thomas Abraham, Shim Chen Kiong, Thaddius Herman Maling, Senthilmani Rajendran, Sok Ching Cheong
Publikováno v:
Dentistry Journal, Vol 10, Iss 11, p 199 (2022)
This study aims to evaluate the time-to-treatment of oral cancer and potentially malignant oral disorders (PMOD) in a Malaysian public healthcare setting while exploring its contributing factors. It consists of (1) a cross-sectional patient survey to
Externí odkaz:
https://doaj.org/article/786008f8145f455db275045361d7a51c
Autor:
Yin-Ling Wong, Anand Ramanathan, Kar Mun Yuen, Wan Mahadzir Wan Mustafa, Mannil Thomas Abraham, Keng Kiong Tay, Zainal Ariff Abdul Rahman, Yeng Chen
Publikováno v:
PeerJ, Vol 9, p e11548 (2021)
Background Oral squamous cell carcinoma (OSCC) has increased in incidence from 1990 to 2017, especially in South and Southeast Asia. It is often diagnosed at an advanced stage with a poor prognosis. Therefore, early detection of OSCC is essential to
Externí odkaz:
https://doaj.org/article/e0d0253a103d42fcaf17bf7a55c14e5d
Autor:
Sivaraj Raman, Asrul Akmal Shafie, Mannil Thomas Abraham, Chen Kiong Shim, Thaddius Herman Maling, Senthilmani Rajendran, Sok Ching Cheong
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251760 (2021)
Oral cancer has been recognized as a significant challenge to healthcare. In Malaysia, numerous patients frequently present with later stages of cancers to the highly subsidized public healthcare facilities. Such a trend contributes to a substantial
Externí odkaz:
https://doaj.org/article/6cb84060ef3c4735ad6a6702c43163d4
Autor:
Vui King Vincent-Chong, Iman Salahshourifar, Kar Mun Woo, Arif Anwar, Rozaimi Razali, Ranganath Gudimella, Zainal Ariff Abdul Rahman, Siti Mazlipah Ismail, Thomas George Kallarakkal, Anand Ramanathan, Wan Mahadzir Wan Mustafa, Mannil Thomas Abraham, Keng Kiong Tay, Rosnah Binti Zain
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0174865 (2017)
BACKGROUND:Cancers of the oral cavity are primarily oral squamous cell carcinomas (OSCCs). Many of the OSCCs present at late stages with an exceptionally poor prognosis. A probable limitation in management of patients with OSCC lies in the insufficie
Externí odkaz:
https://doaj.org/article/6b4773035b5348bd948bc3346e40040e
Autor:
Yink Heay Kong, Sharifah Nurain Syed Zanaruddin, Shin Hin Lau, Anand Ramanathan, Thomas George Kallarakkal, Vui King Vincent-Chong, Wan Mahadzir Wan Mustafa, Mannil Thomas Abraham, Zainal Ariff Abdul Rahman, Rosnah Binti Zain, Sok Ching Cheong
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134045 (2015)
Oral squamous cell carcinoma (OSCC) is an aggressive disease accounting for more than 260,000 cancer cases diagnosed and 128,000 deaths worldwide. A large majority of cancer deaths result from cancers that have metastasized beyond the primary tumor.
Externí odkaz:
https://doaj.org/article/730f280b845b46368030592a12606e17
Autor:
Vui King Vincent-Chong, Iman Salahshourifar, Lee Peng Karen-Ng, Ming Yhong Siow, Thomas George Kallarakkal, Anand Ramanathan, Yi-Hsin Yang, Goot Heah Khor, Zainal Ariff Abdul Rahman, Siti Mazlipah Ismail, Narayanan Prepageran, Wan Mahadzir Wan Mustafa, Mannil Thomas Abraham, Keng Kiong Tay, Sok Ching Cheong, Rosnah Binti Zain
Publikováno v:
The Scientific World Journal, Vol 2014 (2014)
Matrix metalloproteinase 13 (MMP13) plays a central role in the MMP activation cascade that enables degradation of the extracellular matrix and basement membranes, and it is identified as a potential driver in oral carcinogenesis. Therefore, this stu
Externí odkaz:
https://doaj.org/article/aad56cf16fbd427192cf89d8221db4cd
Autor:
Kue Peng Lim, Nicole Ai Leng Chun, Siti Mazlipah Ismail, Mannil Thomas Abraham, Mohd Nury Yusoff, Rosnah Binti Zain, Wei Cheong Ngeow, Sathibalan Ponniah, Sok Ching Cheong
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103975 (2014)
Regulatory T cells (Tregs), a subset of CD4+ T cells plays a pivotal role in regulating the immune system. An increase in Treg numbers enables cancer progression by dampening the immune system and allowing tumor cells to evade immune detection and de
Externí odkaz:
https://doaj.org/article/6ddb7292674a4a269ca2299e8f4ffb65
Autor:
Vui King Vincent-Chong, Arif Anwar, Lee Peng Karen-Ng, Sok Ching Cheong, Yi-Hsin Yang, Padmaja Jayaprasad Pradeep, Zainal Ariff Abdul Rahman, Siti Mazlipah Ismail, Zuraiza Mohamad Zaini, Narayanan Prepageran, Thomas George Kallarakkal, Anand Ramanathan, Nur Aaina Binti Mohd Mohayadi, Nurul Shielawati Binti Mohamed Rosli, Wan Mahadzir Wan Mustafa, Mannil Thomas Abraham, Keng Kiong Tay, Rosnah Binti Zain
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e54705 (2013)
Despite the advances in diagnosis and treatment of oral squamous cell carcinoma (OSCC), mortality and morbidity rates have not improved over the past decade. A major drawback in diagnosis and treatment of OSCC is the lack of knowledge relating to how
Externí odkaz:
https://doaj.org/article/b556b6e3499243d299dc70b8f4baae2e