Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Mann‑Jen Hour"'
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background This retrospective cohort study examined the impact of tetracyclines (TCs) and proton pump inhibitors (PPIs) alone or in combination on the efficacy of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) in pat
Externí odkaz:
https://doaj.org/article/0de2f653013e45c78aea54a2ef5e9ddc
Publikováno v:
Therapeutic Advances in Drug Safety, Vol 14 (2023)
Background: Clinical trials investigating the effects of beta-blockers (BBs) on cancer are underway. Evidence from preclinical research suggests that BBs could serve as anticancer agents and immune boosters. There is conflicting evidence regarding th
Externí odkaz:
https://doaj.org/article/32467566ff2f4eb495c93b46b57e415b
Publikováno v:
Integrative Cancer Therapies, Vol 22 (2023)
Background: Non-cancer drugs are currently being repurposed for cancer treatment. Mounting evidence highlights the influence of calcium channels on tumorigenesis and progression. Hence, inhibition of calcium signaling may be a promising cancer treatm
Externí odkaz:
https://doaj.org/article/ed736efb5b934b8286d1f14cc5454e5b
Autor:
Mann-Jen Hour, Yeh Chen, Chen-Sheng Lin, Lidia A. Baltina, Ju-Ying Kan, Yan-Ting Tsai, Yan-Tung Kiu, Hsueh-Chou Lai, Lia A. Baltina, Svetlana F. Petrova, Cheng-Wen Lin
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10309 (2022)
Dengue virus (DENV) is one of the most geographically distributed mosquito-borne flaviviruses, like Japanese encephalitis virus (JEV), and Zika virus (ZIKV). In this study, a library of the known and novel Glycyrrhizic acid (GL) derivatives bearing a
Externí odkaz:
https://doaj.org/article/bcb83f3da0d64504b5c01b2fe42223ba
Autor:
Ching-Ying Wang, An-Cheng Huang, Mann-Jen Hour, Su-Hua Huang, Szu-Hao Kung, Chao-Hsien Chen, I-Chieh Chen, Yuan-Shiun Chang, Jin-Cherng Lien, Cheng-Wen Lin
Publikováno v:
Viruses, Vol 7, Iss 6, Pp 3155-3171 (2015)
Enterovirus A71 (EV-A71) in the Picornaviridae family causes hand-foot-and-mouth disease, aseptic meningitis, severe central nervous system disease, even death. EV-A71 2A protease cleaves Type I interferon (IFN)-α/β receptor 1 (IFNAR1) to block IFN
Externí odkaz:
https://doaj.org/article/67718cd19cac493ebfd335015c8ec4ad
Autor:
Chien-Yi Lu, Yi-Chih Chang, Chun-Hung Hua, Chieh Chuang, Su-Hua Huang, Szu-Hao Kung, Mann-Jen Hour, Cheng-Wen Lin
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 5, p 954 (2017)
Japanese encephalitis virus (JEV), a neurotropic flavivirus, annually causes over 30,000 Japanese Encephalitis (JE) cases in East and Southeast Asia. Histone deacetylases (HDACs) modulate lysine acetylation of histones and non-histone proteins, regul
Externí odkaz:
https://doaj.org/article/61616577fdc4470fa3f51204c0595c80
Autor:
Chien-Yi Lu, Mann-Jen Hour, Ching-Ying Wang, Su-Hua Huang, Wen-Xiang Mu, Yu-Chun Chang, Cheng-Wen Lin
Publikováno v:
Viruses, Vol 9, Iss 4, p 76 (2017)
Japanese Encephalitis virus (JEV) is a mosquito-borne flavivirus with a positive-sense single-stranded RNA genome that contains a big open reading frame (ORF) flanked by 5′- and 3′- untranslated regions (UTRs). Nearly 30,000 JE cases with 10,000
Externí odkaz:
https://doaj.org/article/f079b34a788b49059dfe2d6e55337cc9
Autor:
Han-Ching Lin, Tzu-Hung Lin, Ming-Yueh Wu, Yung-Cheng Chiu, Chih-Hsin Tang, Mann-Jen Hour, Houng-Chi Liou, Huang-Ju Tu, Rong-Sen Yang, Wen-Mei Fu
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107890 (2014)
The lipoxygenase isoform of 5-lipoxygenase (5-LOX) is reported to be overexpressed in human rheumatoid arthritis synovial tissue and involved in the progress of inflammatory arthritis. However, the detailed mechanism of how 5-lipoxygenase regulates t
Externí odkaz:
https://doaj.org/article/9fb9451055a4499eb6ea38273e2c8efd
Autor:
Chi-Cheng Lu, Jai-Sing Yang, Jo-Hua Chiang, Mann-Jen Hour, Kuei-Li Lin, Jen-Jyh Lin, Wen-Wen Huang, Minoru Tsuzuki, Tsung-Han Lee, Jing-Gung Chung
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36831 (2012)
The present study was to explore the biological responses of the newly compound, MJ-29 in murine myelomonocytic leukemia WEHI-3 cells in vitro and in vivo fates. We focused on the in vitro effects of MJ-29 on ER stress and mitochondria-dependent apop
Externí odkaz:
https://doaj.org/article/033ca8ad6c8b4eeda4706d318a39f42d
Autor:
Mann-Jen Hour, 侯曼貞
88
As part of our continuing search for potential anticancer candidates of 2-phenyl-4-quinazolinones and 2-phenyl-4-quinolones, two series of 6,7,2',3',4',5'-substituted 2-phenyl-4-quinazolinones and 6,2',3',4',5'-substituted 2,3-dihydro-2-pheny
As part of our continuing search for potential anticancer candidates of 2-phenyl-4-quinazolinones and 2-phenyl-4-quinolones, two series of 6,7,2',3',4',5'-substituted 2-phenyl-4-quinazolinones and 6,2',3',4',5'-substituted 2,3-dihydro-2-pheny
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/66215076548891573814