Prioritization of Drug Targets for Neurodegenerative Diseases by Integrating Genetic and Proteomic Data From Brain and Blood

Autor: Ferrari, Raffaele, Hernandez, Dena G., Nalls, Michael A., Rohrer, Jonathan D., Ramasamy, Adaikalavan, Kwok, John B.J., Dobson-Stone, Carol, Brooks, William S., Schofield, Peter R., Halliday, Glenda M., Hodges, John R., Piguet, Olivier, Bartley, Lauren, Thompson, Elizabeth, Haan, Eric, Hernández, Isabel, Ruiz, Agustín, Boada, Mercè, Borroni, Barbara, Padovani, Alessandro, Cruchaga, Carlos, Cairns, Nigel J., Benussi, Luisa, Binetti, Giuliano, Ghidoni, Roberta, Forloni, Gianluigi, Galimberti, Daniela, Fenoglio, Chiara, Serpente, Maria, Scarpini, Elio, Clarimón, Jordi, Lleó, Alberto, Blesa, Rafael, Waldö, Maria Landqvist, Nilsson, Karin, Nilsson, Christer, Mackenzie, Ian R.A., Hsiung, Ging-Yuek R., Mann, David M.A., Grafman, Jordan, Morris, Christopher M., Attems, Johannes, Griffiths, Timothy D., McKeith, Ian G., Thomas, Alan J., Pietrini, P., Huey, Edward D., Wassermann, Eric M., Baborie, Atik, Jaros, Evelyn, Tierney, Michael C., Pastor, Pau, Razquin, Cristina, Ortega-Cubero, Sara, Alonso, Elena, Perneczky, Robert, Diehl-Schmid, Janine, Alexopoulos, Panagiotis, Kurz, Alexander, Rainero, Innocenzo, Rubino, Elisa, Pinessi, Lorenzo, Rogaeva, Ekaterina, St. George-Hyslop, Peter, Rossi, Giacomina, Tagliavini, Fabrizio, Giaccone, Giorgio, Rowe, James B., Schlachetzki, Johannes C.M., Uphill, James, Collinge, John, Mead, Simon, Danek, Adrian, Van Deerlin, Vivianna M., Grossman, Murray, Trojanowski, John Q., van der Zee, Julie, Deschamps, William, Van Langenhove, Tim, Cruts, Marc, Van Broeckhoven, Christine, Cappa, Stefano F., Le Ber, Isabelle, Hannequin, Didier, Golfier, Véronique, Vercelletto, Martine, Brice, Alexis, Nacmias, Benedetta, Sorbi, Sandro, Bagnoli, Silvia, Piaceri, Irene, Nielsen, Jørgen E., Hjermind, Lena E., Riemenschneider, Matthias, Mayhaus, Manuel, Ibach, Bernd, Gasparoni, Gilles, Pichler, Sabrina, Gu, Wei, Rossor, Martin N., Fox, Nick C., Warren, Jason D., Spillantini, Maria Grazia, Morris, Huw R., Rizzu, Patrizia, Heutink, Peter, Snowden, Julie S., Rollinson, Sara, Richardson, Anna, Gerhard, Alexander, Bruni, Amalia C., Maletta, Raffaele, Frangipane, Francesca, Cupidi, Chiara, Bernardi, Livia, Anfossi, Maria, Gallo, Maura, Conidi, Maria Elena, Smirne, Nicoletta, Rademakers, Rosa, Baker, Matt, Dickson, Dennis W., Graff-Radford, Neill R., Petersen, Ronald C., Knopman, David, Josephs, Keith A., Boeve, Bradley F., Parisi, Joseph E., Seeley, William W., Miller, Bruce L., Karydas, Anna M., Rosen, Howard, van Swieten, John C., Dopper, Elise G.P., Seelaar, Harro, Pijnenburg, Yolande A.L., Scheltens, Philip, Logroscino, Giancarlo, Capozzo, Rosa, Novelli, Valeria, Puca, Annibale A., Franceschi, Massimo, Postiglione, Alfredo, Milan, Graziella, Sorrentino, Paolo, Kristiansen, Mark, Chiang, Huei-Hsin, Graff, Caroline, Pasquier, Florence, Rollin, Adeline, Deramecourt, Vincent, Lebert, Florence, Kapogiannis, Dimitrios, Ferrucci, Luigi, Pickering-Brown, Stuart, Singleton, Andrew B., Hardy, John, Momeni, Parastoo, Ge, Yi-Jun ^{a, 1}, Ou, Ya-Nan ^{a, 1}, Deng, Yue-Ting ^b, Wu, Bang-Sheng ^b, Yang, Liu ^b, Zhang, Ya-Ru ^b, Chen, Shi-Dong ^b, Huang, Yu-Yuan ^b, Dong, Qiang ^b, Tan, Lan ^a, Yu, Jin-Tai ^{b, ∗}

Publikováno v: In Biological Psychiatry 1 May 2023 93(9):770-779

Self-Reported Late-Life Hypertension Is Associated with a Healthy Cognitive Status and Reduced Alzheimer's Disease Pathology Burden.

Autor: Robinson, Andrew C., Bin Rizwan, Tawfique, Davidson, Yvonne S., Minshull, James, Tinkler, Phillip, Payton, Antony, Mann, David M.A., Roncaroli, Federico

Publikováno v: Journal of Alzheimer's Disease; 2024, Vol. 98 Issue 4, p1457-1466, 10p

Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology

Autor: Vaikath, Nishant N. ^{a, b}, Majbour, Nour K. ^{a, c}, Paleologou, Katerina E. ^d, Ardah, Mustafa T. ^a, van Dam, Esther ^c, van de Berg, Wilma D.J. ^c, Forrest, Shelley L. ^e, Parkkinen, Laura ^f, Gai, Wei-Ping ^g, Hattori, Nobutaka ^{h, i}, Takanashi, Masashi ⁱ, Lee, Seung-Jae ^j, Mann, David M.A. ^k, Imai, Yuzuru ^h, Halliday, Glenda M. ^l, Li, Jia-Yi. ^b, El-Agnaf, Omar M.A. ^{a, m, ⁎}

Publikováno v: In Neurobiology of Disease July 2015 79:81-99

Prion-like Properties of Pathological TDP-43 Aggregates from Diseased Brains

Autor: Nonaka, Takashi ^{1, ∗}, Masuda-Suzukake, Masami ¹, Arai, Tetsuaki ^{2, 3}, Hasegawa, Yoko ¹, Akatsu, Hiroyasu ⁴, Obi, Tomokazu ⁵, Yoshida, Mari ⁶, Murayama, Shigeo ⁷, Mann, David M.A. ⁸, Akiyama, Haruhiko ², Hasegawa, Masato ^{1, ∗∗}

Publikováno v: In Cell Reports 11 July 2013 4(1):124-134

Glucocerebrosidase mutations in diffuse Lewy body disease

Autor: Nishioka, Kenya ^a, Ross, Owen A. ^a, Vilariño-Güell, Carles ^{a, h}, Cobb, Stephanie A. ^a, Kachergus, Jennifer M. ^a, Mann, David M.A. ^b, Snowden, Julie ^b, Richardson, Anna M.T. ^b, Neary, David ^b, Robinson, Christopher A. ^c, Rajput, Alex ^{c, d}, Papapetropoulos, Spiridon ^e, Mash, Deborah C. ^e, Pahwa, Rajesh ^f, Lyons, Kelly E. ^f, Wszolek, Zbigniew K. ^g, Dickson, Dennis W. ^a, Farrer, Matthew J. ^{a, h, ∗}

Publikováno v: In Parkinsonism and Related Disorders January 2011 17(1):55-57