Viral emissions into the air and environment after SARS-CoV-2 human challenge: a phase 1, open label, first-in-human study

Autor: Zhou, Jie ^†, Singanayagam, Anika ^†, Goonawardane, Niluka, Moshe, Maya, Sweeney, Fiachra P, Sukhova, Ksenia, Killingley, Ben, Kalinova, Mariya, Mann, Alex J, Catchpole, Andrew P, Barer, Michael R, Ferguson, Neil M, Chiu, Christopher, Barclay, Wendy S ^*

Publikováno v: In The Lancet Microbe

Intranasal H5N1 Vaccines, Adjuvanted with Chitosan Derivatives, Protect Ferrets against Highly Pathogenic Influenza Intranasal and Intratracheal Challenge.

Autor: Mann, Alex J.¹ a.mann@retroscreen.com, Noulin, Nicolas¹, Catchpole, Andrew¹, Stittelaar, Koert J.², de Waal, Leon², Veldhuis Kroeze, Edwin J. B.², Hinchcliffe, Michael³, Smith, Alan³, Montomoli, Emanuele^4,5, Piccirella, Simona⁵, Osterhaus, Albert D. M. E.^2,6, Knight, Alastair⁷, Oxford, John S.¹, Lapini, Giulia⁴, Cox, Rebecca^8,9, Lambkin-Williams, Rob¹

Publikováno v: PLoS ONE. May2014, Vol. 9 Issue 5, p1-11. 11p.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults.

Autor: Killingley B; Department of Infectious Diseases, University College London Hospital, London, UK., Mann AJ; hVIVO Services Ltd., London, UK., Kalinova M; hVIVO Services Ltd., London, UK., Boyers A; hVIVO Services Ltd., London, UK., Goonawardane N; Department of Infectious Disease, Imperial College London, London, UK., Zhou J; Department of Infectious Disease, Imperial College London, London, UK., Lindsell K; UK Vaccine Taskforce, Department for Business, Energy and Industrial Strategy, London, UK., Hare SS; Department of Radiology, Royal Free London NHS Foundation Trust, London, UK., Brown J; Department of Infectious Disease, Imperial College London, London, UK., Frise R; Department of Infectious Disease, Imperial College London, London, UK., Smith E; National Heart and Lung Institute, Imperial College London, London, UK., Hopkins C; ENT Department, Guy's and St. Thomas' NHS Foundation Trust, London, UK., Noulin N; hVIVO Services Ltd., London, UK., Löndt B; hVIVO Services Ltd., London, UK., Wilkinson T; Faculty of Medicine and Institute for Life Sciences, University of Southampton, and NIHR Southampton Biomedical Research Centre, University Hospital Southampton, Southampton, UK., Harden S; Department of Radiology, Southampton General Hospital, Southampton, UK., McShane H; Department of Paediatrics, University of Oxford, Oxford, UK., Baillet M; S-cubed Biometrics, Abingdon, UK., Gilbert A; UK Vaccine Taskforce, Department for Business, Energy and Industrial Strategy, London, UK., Jacobs M; Department of Infectious Diseases, Royal Free London NHS Foundation Trust, London, UK., Charman C; UK Vaccine Taskforce, Department for Business, Energy and Industrial Strategy, London, UK., Mande P; UK Vaccine Taskforce, Department for Business, Energy and Industrial Strategy, London, UK., Nguyen-Van-Tam JS; Division of Epidemiology and Public Health, University of Nottingham School of Medicine, Nottingham, UK., Semple MG; Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool; Respiratory Department, Alder Hey Children's Hospital, Liverpool, UK., Read RC; Faculty of Medicine and Institute for Life Sciences, University of Southampton, and NIHR Southampton Biomedical Research Centre, University Hospital Southampton, Southampton, UK., Ferguson NM; MRC Centre for Global Infectious Disease Analysis, School of Public Health, Imperial College London, London, UK., Openshaw PJ; National Heart and Lung Institute, Imperial College London, London, UK., Rapeport G; National Heart and Lung Institute, Imperial College London, London, UK., Barclay WS; Department of Infectious Disease, Imperial College London, London, UK., Catchpole AP; hVIVO Services Ltd., London, UK., Chiu C; Department of Infectious Disease, Imperial College London, London, UK. c.chiu@imperial.ac.uk.

Publikováno v: Nature medicine [Nat Med] 2022 May; Vol. 28 (5), pp. 1031-1041. Date of Electronic Publication: 2022 Mar 31.