Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Manmohan S Bajaj"'
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50153 (2012)
HT1080 - a human fibrosarcoma-derived cell line - forms aggressive angiogenic tumours in immuno-compromised mice. In spite of its extensive use as a model of tumour angiogenesis, the molecular event(s) initiating the angiogenic program in these cells
Externí odkaz:
https://doaj.org/article/e1fe4542706e4a4eb7204bd8155a4c47
Publikováno v:
Haematologica, Vol 100, Iss 8 (2015)
Externí odkaz:
https://doaj.org/article/6161ed41d64044e39e1f5abd0608e74a
Autor:
Sapana Jalnapurkar, Rohan S. Kulkarni, Suprita S. Ghode, Vaijayanti Kale, Manmohan S. Bajaj, Lalita Limaye
Publikováno v:
Stem Cells. 36:420-433
Donor age is one of the major concerns in bone marrow transplantation, as the aged hematopoietic stem cells (HSCs) fail to engraft efficiently. Here, using murine system, we show that a brief interaction of aged HSCs with young mesenchymal stromal ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e2b404c5f2d8696d56bd48fcda53cef
https://doi.org/10.1002/stem.2756
https://doi.org/10.1002/stem.2756
Autor:
Lalita Limaye, Yogesh S Shouche, Vaijayanti Kale, Suprita S. Ghode, Manmohan S. Bajaj, Rohan S. Kulkarni
Publikováno v:
Stem Cells and Development. 26:35-48
Marrow adipocytes pose a significant problem in post-transplant regeneration of hematopoiesis owing to their negative effects on regeneration of hematopoiesis. However, the precise mechanism operative in this negative regulation is not clear. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c81f23627be78f02d3f487f3c8c5923f
https://doi.org/10.1089/scd.2016.0096
https://doi.org/10.1089/scd.2016.0096
Publikováno v:
Stem Cell Research. 17:646-653
Pre-transplant myeloablation is associated with marrow adipogenesis, resulting in delayed engraftment of hematopoietic stem cells (HSCs). This is strongly undesirable, especially when the donor HSCs are fewer in numbers or have compromised functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4443426d1712dc363eee8836094491f6
https://doi.org/10.1016/j.scr.2016.11.015
https://doi.org/10.1016/j.scr.2016.11.015
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1854
Autophagy is an important cellular process for maintenance of quality and functionality of cells. This happens through repair and renewal of cellular components like proteins and mitochondria. Reduction in autophagy process in aged hematopoietic stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e08885bd748c6c2c28dfd110253b6764
https://pubmed.ncbi.nlm.nih.gov/29951740
https://pubmed.ncbi.nlm.nih.gov/29951740
Publikováno v:
Stem Cell Biology and Regenerative Medicine ISBN: 9783319981451
Stem cell transplantation (SCT) is the only curative therapy for various malignant as well as nonmalignant disorders like leukemia, lymphoma, and aplastic anemia. Efficacy of clinical transplantation critically depends on functionality of the hematop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e8ec4d2fcb1fc1e42e6f396867aab70
https://doi.org/10.1007/978-3-319-98146-8_3
https://doi.org/10.1007/978-3-319-98146-8_3
Publikováno v:
Autophagy in Differentiation and Tissue Maintenance ISBN: 9781493987474
Autophagy is an important cellular process for maintenance of quality and functionality of cells. This happens through repair and renewal of cellular components like proteins and mitochondria. Reduction in autophagy process in aged hematopoietic stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6caafca90a0ab544c94287b23148cdef
https://doi.org/10.1007/7651_2018_166
https://doi.org/10.1007/7651_2018_166
Autor:
Lalita Limaye, Avadhesha Surolia, Rajesh Kumar Gupta, Ashwini Hinge, Manmohan S. Bajaj, Vaijayanti Kale
Publikováno v:
Glycobiology. 21:521-529
We have recently demonstrated that the mannose-binding lectins, namely banana lectin (BL) and garlic lectin (GL), interacted with the insulin receptors on M210B4 cells--an established mesenchymal cell line of murine marrow origin--and initiate mitoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::763fd8117e62e81774d858b3db225d32
https://doi.org/10.1093/glycob/cwq194
https://doi.org/10.1093/glycob/cwq194
Publikováno v:
Haematologica.
Pre-transplant myeloablation increases bone marrow (BM) adipogenesis and destroys the niche cells, adversely affecting the hematopoietic stem cell (HSC) engraftment. This becomes a serious issue when donor HSCs are few or if their functionality is co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55d153e061d902b8b99bf4f5d4230e86
https://doi.org/10.3324/haematol.2015.124750
https://doi.org/10.3324/haematol.2015.124750