Výsledky vyhledávání - "Manling Peng"

Interaction of Echicetin with a High Affinity Thrombin Binding Site on Platelet Glycoprotein GPIb

Autor: Ahua Mao, Edward P. Kirby, Stefan Niewiarowski, F. A. Emig, Manling Peng, M. A. Kowalska, Weiqi Lu

Publikováno v: Thrombosis and Haemostasis. 74:954-957

SummaryEchicetin, a protein isolated from Echis carinatus snake venom, inhibited platelet aggregation and secretion induced by low concentrations of thrombin (0.2 U/ml). Echicetin competed with thrombin for binding to the high affinity site on GPIb.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dec6b2043705496297439a65bce69eb2
https://doi.org/10.1055/s-0038-1649854

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Isolation, Characterization and Amino Acid Sequence of Echicetin β Subunit, a Specific Inhibitor of von Willebrand Factor and Thrombin Interaction with Glycoprotein Ib

Autor: Manling Peng, J. C. Holt, Stefan Niewiarowski

Publikováno v: Biochemical and Biophysical Research Communications. 205:68-72

Echicetin is a dimeric protein isolated from the venom of Echis carinatus that is a potent inhibitor of von Willebrand Factor and thrombin binding to glycoprotein Ib. Here, we report isolation and amino acid sequence of the β subunit of echicetin th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1bddfa752cf13991efddd885a16783e
https://doi.org/10.1006/bbrc.1994.2630

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Alboaggregin-B: a new platelet agonist that binds to platelet membrane glycoprotein Ib

Autor: Edward P. Kirby, Weiqi Lu, Manling Peng

Publikováno v: Biochemistry. 30:11529-11536

A new protein, called alboaggregin-B (AL-B), has been isolated from Trimeresurus albolabris venom by ion-exchange chromatography. It agglutinated platelets without the need for Ca2+ or any other cofactor. The purified protein showed an apparent molec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe6789bb74b928515e2a858dc5127a8
https://doi.org/10.1021/bi00113a007

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Separation of different receptor-mediated effects of a prostaglandin H2 analogue (U46619) on human platelets by means of human granulocytic elastase and chymotrypsin

Autor: Hanna Lukasiewicz, T. A. Morinelli, Edward P. Kirby, Annette Eckardt, Manling Peng, Stefan Niewiarowski

Publikováno v: Biochemical Pharmacology. 38:3213-3217

Previous investigations indicated two classes of thromboxane A 2 /prostaglandin H 2 (TXA 2 /PGH 2 ) receptors on human platelets and suggested that shape change and myosin light chain phosphorylation correlated with the occupancy of high affinity rec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6246c4b229f0297feccddaa29102e537
https://doi.org/10.1016/0006-2952(89)90616-3

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Alboaggregins A and B. Structure and interaction with human platelets

Autor: J. Karczewski, Manling Peng, J. C. Holt, Stefan Niewiarowski, Li Tan, M. A. Kowalska, Juan J. Calvete

Publikováno v: Europe PubMed Central
CIÊNCIAVITAE
Scopus-Elsevier

SummaryViper venoms contain a variety of platelet binding proteins including those which bind to platelet GPIb/GPIX. Most of these proteins inhibit von Willebrand factor mediated platelet agglutination. Here we report the primary structures of unique

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84a64c60edc7236ddcebb1daea2bf830
http://europepmc.org/abstract/med/9531050

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