Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Mankil Jung"'
Autor:
Gwang Taek Ma, Sun Kyoung Lee, Kwang-Kyun Park, Junhee Park, Seung Hwa Son, Mankil Jung, Won-Yoon Chung
Publikováno v:
Cellular Physiology and Biochemistry, Vol 49, Iss 4, Pp 1460-1475 (2018)
Background/Aims: Bone metastasis of cancer cells decreases patient survival and quality of life. Hybridization via the covalent coupling of two bioactive natural products is a useful strategy for developing more potent anticancer agents by enhancing
Externí odkaz:
https://doaj.org/article/16139dd1dc234c44b333a2d4531476a9
Publikováno v:
Molecules, Vol 17, Iss 9, Pp 10446-10458 (2012)
Simple synthesis of modafinil derivatives and their biological activity are described. The key synthetic strategies involve substitution and coupling reactions. We determined the anti-inflammatory effects of modafinil derivatives in cultured BV2 cell
Externí odkaz:
https://doaj.org/article/9b18e2ed48414988892dd976b626bacf
Autor:
Mankil Jung, Oee-Sook Park, Jeremy Ricci, Dongguk Min, Yongnam Lee, Jae-Chul Jung, Eunyoung Lim
Publikováno v:
Molecules, Vol 17, Iss 2, Pp 2091-2102 (2012)
The total synthesis and structure determination of cis- and trans-flocoumafen was described. The key synthetic steps involve Knoevenagel condensation with p-methoxybenzaldehyde, in situ decarboxylation and intramolecular ring cyclization to construct
Externí odkaz:
https://doaj.org/article/779a967a905c4b439425469b15202f37
Publikováno v:
Molecules, Vol 16, Iss 12, Pp 10409-10419 (2011)
Simple synthesis and biological activities of modafinil derivatives are described. The key reactions include condensation of acid and propargyl alcohol, subsequent 1,3-dipolar cycloaddition reaction of alkynes and (3-azido-propyl)cyclohexane or (4-az
Externí odkaz:
https://doaj.org/article/e12fafdd6b294cb4bf438c10882e0a98
Publikováno v:
Molecules, Vol 16, Iss 12, Pp 9886-9899 (2011)
Dimethyl lithosermate B (DLB) is a highly potent natural antioxidant and antidiabetic polyphenol with unknown mode of action. To determine its cellular targets, a photochemical and fluorescent dimethyl lithopermate B probe was designed and efficientl
Externí odkaz:
https://doaj.org/article/66809372dc954acf8827d69820549ac5
Autor:
Moonso Park, Mankil Jung
Publikováno v:
Molecules, Vol 12, Iss 9, Pp 2130-2139 (2007)
In a bioassay-guided search for acetylcholinesterase (AChE) inhibitors from 180 medicinal plants, an ethyl acetate extract of whole plants of Agrimonia pilosa ledeb yielded tiliroside (1), 3-methoxy quercetin (2), quercitrin (3) and quercetin (4). We
Externí odkaz:
https://doaj.org/article/2fba33dc381c406793170e8ec191e116
Publikováno v:
Molecules, Vol 22, Iss 11, p 1872 (2017)
Practical synthesis and biological activities of 4-hydroxy-3-methoxy-2-propene derivatives are described. The novel chalcone derivatives were prepared by acid catalysed one-step condensation of 1,3- or 1,4-diacetylbenzene and 1,3,5-triacetylbenzene w
Externí odkaz:
https://doaj.org/article/f4c013d231de4e48a420cc3ddf9a41bd
Autor:
Jun-Hee Park, Won Yoon Chung, Gwang Taek Ma, Mankil Jung, Sun Kyoung Lee, Kwang Kyun Park, Seung Hwa Son
Publikováno v:
Cellular Physiology and Biochemistry, Vol 49, Iss 4, Pp 1460-1475 (2018)
Background/Aims: Bone metastasis of cancer cells decreases patient survival and quality of life. Hybridization via the covalent coupling of two bioactive natural products is a useful strategy for developing more potent anticancer agents by enhancing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be88f5f1bafa188eb55bd942bb2622e3
https://www.karger.com/Article/FullText/493449
https://www.karger.com/Article/FullText/493449
Autor:
Miyeon Oh, Mankil Jung, Hyenchong Lim, Won Yoon Chung, Jeremy Ricci, Kwang Kyun Park, Dongguk Min
Publikováno v:
Medicinal Chemistry. 11:747-752
Daumone, a dauer-inducing pheromone and a series of lipid derivatives were synthesized from daumone to investigate structure-activity trends. Lipid derivatives demonstrated potent in vivo antiangiogenic activity on the chorioallantoic membrane, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f0f251afc331828a4efc914af2d80f
https://doi.org/10.2174/1573406411666150514100630
https://doi.org/10.2174/1573406411666150514100630
Publikováno v:
CHEMICAL & PHARMACEUTICAL BULLETIN. 63:843-847
The first total synthesis for large-scale production and anticancer activity of novel aminophenylpyridinium-5-(hydroxybenzoyl)hydrazonomethyl-2-oxothiazol-3-ide (PBHT) (1) and its derivatives are reported. The chemical structure of PBHT was unambiguo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eafc6d56f5880e112f39397c1c002f16
https://doi.org/10.1248/cpb.c15-00441
https://doi.org/10.1248/cpb.c15-00441