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Akademický článek

Deletions in the MAL gene result in loss of Mal protein, defining the rare inherited AnWj-negative blood group phenotype.

Autor: Tilley LA; International Blood Group Reference Laboratory, National Health Service Blood and Transplant, Bristol, United Kingdom., Karamatic Crew V; International Blood Group Reference Laboratory, National Health Service Blood and Transplant, Bristol, United Kingdom., Mankelow TJ; International Blood Group Reference Laboratory, National Health Service Blood and Transplant, Bristol, United Kingdom.; Component Development Laboratory, National Health Service Blood and Transplant, Cambridge, United Kingdom., AlSubhi SA; International Blood Group Reference Laboratory, National Health Service Blood and Transplant, Bristol, United Kingdom.; School of Biochemistry, University of Bristol, Bristol, United Kingdom.; Laboratory Medicine Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, Saudi Arabia., Jones B; International Blood Group Reference Laboratory, National Health Service Blood and Transplant, Bristol, United Kingdom., Borowski A; International Blood Group Reference Laboratory, National Health Service Blood and Transplant, Bristol, United Kingdom., Yahalom V; Blood Services and Apheresis Institute, Rabin Medical Center, Petah Tiqva, Israel.; Faculty of Medical and Health Science, Tel Aviv University, Tel Aviv, Israel., Finkel L; National Blood Group Reference Laboratory, Magen David Adom National Blood Services, Ramla, Israel., Singleton BK; National Institute for Health and Care Research Blood and Transplant Research Unit in Genomics to Enhance Microbiology Screening, National Health Service Blood and Transplant, Bristol, United Kingdom., Walser PJ; Clinical Biotechnology Centre, National Health Service Blood and Transplant, Bristol, United Kingdom., Toye AM; School of Biochemistry, University of Bristol, Bristol, United Kingdom.; National Institute for Health and Care Research Blood and Transplant Research Unit in Red Blood Cell Products, University of Bristol, Bristol, United Kingdom., Satchwell TJ; School of Biochemistry, University of Bristol, Bristol, United Kingdom.; National Institute for Health and Care Research Blood and Transplant Research Unit in Red Blood Cell Products, University of Bristol, Bristol, United Kingdom., Thornton NM; International Blood Group Reference Laboratory, National Health Service Blood and Transplant, Bristol, United Kingdom.

Publikováno v: Blood [Blood] 2024 Dec 26; Vol. 144 (26), pp. 2735-2747.

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Editorial & Opinion

Higher levels of von Willebrand factor in hospitalised patient plasma provides an explanation for the association of ABO blood group and secretor status with COVID19 severity.

Autor: Mankelow TJ; Bristol Institute for Transfusion Sciences, NHSBT, Bristol, UK.; NIHR Blood and Transplant Research Unit in Red Cell Products, University of Bristol, Bristol, UK., Blair A; Bristol Institute for Transfusion Sciences, NHSBT, Bristol, UK.; NIHR Blood and Transplant Research Unit in Red Cell Products, University of Bristol, Bristol, UK., Arnold DT; Infection Sciences, Southmead Hospital North Bristol NHS Trust, Bristol, UK., Hamilton FW; Infection Sciences, Southmead Hospital North Bristol NHS Trust, Bristol, UK.; Population Health Sciences, University of Bristol, Bristol, UK., Gillespie KM; Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Anstee DJ; Bristol Institute for Transfusion Sciences, NHSBT, Bristol, UK.; NIHR Blood and Transplant Research Unit in Red Cell Products, University of Bristol, Bristol, UK., Toye AM; Bristol Institute for Transfusion Sciences, NHSBT, Bristol, UK.; NIHR Blood and Transplant Research Unit in Red Cell Products, University of Bristol, Bristol, UK.

Publikováno v: Transfusion medicine (Oxford, England) [Transfus Med] 2022 Jun; Vol. 32 (3), pp. 261-262. Date of Electronic Publication: 2022 Mar 24.

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Akademický článek

Large red cell-derived membrane particles are major contributors to hypercoagulability in sickle cell disease.

Autor: Smith RA; Bristol Institute for Transfusion Sciences, National Health Service Blood and Transplant, Northway, Filton, Bristol, BS34 7QH, UK.; NIHR Blood and Transplant Research Unit, University of Bristol, Bristol, UK.; School of Biochemistry, University of Bristol, Bristol, UK., Mankelow TJ; Bristol Institute for Transfusion Sciences, National Health Service Blood and Transplant, Northway, Filton, Bristol, BS34 7QH, UK. tosti.mankelow@nhsbt.nhs.uk.; NIHR Blood and Transplant Research Unit, University of Bristol, Bristol, UK. tosti.mankelow@nhsbt.nhs.uk., Drizou D; Bristol Institute for Transfusion Sciences, National Health Service Blood and Transplant, Northway, Filton, Bristol, BS34 7QH, UK.; NIHR Blood and Transplant Research Unit, University of Bristol, Bristol, UK.; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Bullock T; Bristol Institute for Transfusion Sciences, National Health Service Blood and Transplant, Northway, Filton, Bristol, BS34 7QH, UK., Latham T; Bristol Institute for Transfusion Sciences, National Health Service Blood and Transplant, Northway, Filton, Bristol, BS34 7QH, UK., Trompeter S; Joint Red Cell Unit, Haematology Department, University College London National Health Service Foundation Trust, London, UK., Blair A; Bristol Institute for Transfusion Sciences, National Health Service Blood and Transplant, Northway, Filton, Bristol, BS34 7QH, UK.; NIHR Blood and Transplant Research Unit, University of Bristol, Bristol, UK.; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Anstee DJ; Bristol Institute for Transfusion Sciences, National Health Service Blood and Transplant, Northway, Filton, Bristol, BS34 7QH, UK.; NIHR Blood and Transplant Research Unit, University of Bristol, Bristol, UK.

Publikováno v: Scientific reports [Sci Rep] 2021 May 26; Vol. 11 (1), pp. 11035. Date of Electronic Publication: 2021 May 26.

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Akademický článek

Blood group type A secretors are associated with a higher risk of COVID-19 cardiovascular disease complications.

Autor: Mankelow TJ; Bristol Institute for Transfusion Sciences (BITS) NHSBT, Filton Bristol UK.; NIHR Blood and Transplant Research Unit in Red Cell Products Bristol UK., Singleton BK; Bristol Institute for Transfusion Sciences (BITS) NHSBT, Filton Bristol UK.; NIHR Blood and Transplant Research Unit in Red Cell Products Bristol UK., Moura PL; Center for Hematology and Regenerative Medicine Department of Medicine (MedH) Karolinska Institutet Stockholm Sweden., Stevens-Hernandez CJ; Bristol Institute for Transfusion Sciences (BITS) NHSBT, Filton Bristol UK.; NIHR Blood and Transplant Research Unit in Red Cell Products Bristol UK.; School of Biochemistry Biomedical Sciences Building University of Bristol Bristol UK., Cogan NM; Bristol Institute for Transfusion Sciences (BITS) NHSBT, Filton Bristol UK.; NIHR Blood and Transplant Research Unit in Red Cell Products Bristol UK., Gyorffy G; Bristol Institute for Transfusion Sciences (BITS) NHSBT, Filton Bristol UK.; NIHR Blood and Transplant Research Unit in Red Cell Products Bristol UK.; School of Biochemistry Biomedical Sciences Building University of Bristol Bristol UK., Kupzig S; Bristol Institute for Transfusion Sciences (BITS) NHSBT, Filton Bristol UK.; NIHR Blood and Transplant Research Unit in Red Cell Products Bristol UK., Nichols L; Acute Medical Unit, Southmead Hospital North Bristol NHS Trust Bristol UK., Asby C; Acute Medical Unit, Southmead Hospital North Bristol NHS Trust Bristol UK., Pooley J; Acute Medical Unit, Southmead Hospital North Bristol NHS Trust Bristol UK., Ruffino G; Acute Medical Unit, Southmead Hospital North Bristol NHS Trust Bristol UK., Hosseini F; Acute Medical Unit, Southmead Hospital North Bristol NHS Trust Bristol UK., Moghaddas F; Acute Medical Unit, Southmead Hospital North Bristol NHS Trust Bristol UK., Attwood M; Infection Sciences, Southmead Hospital North Bristol NHS Trust Bristol UK., Noel A; Infection Sciences, Southmead Hospital North Bristol NHS Trust Bristol UK., Cooper A; Infection Sciences, Southmead Hospital North Bristol NHS Trust Bristol UK., Arnold DT; Infection Sciences, Southmead Hospital North Bristol NHS Trust Bristol UK., Hamilton F; Infection Sciences, Southmead Hospital North Bristol NHS Trust Bristol UK.; Population Health Sciences University of Bristol Bristol UK., Hyams C; Acute Medical Unit, Southmead Hospital North Bristol NHS Trust Bristol UK.; Academic Respiratory Unit Southmead Hospital North Bristol NHS Trust Bristol UK.; Population Health Sciences University of Bristol Bristol UK., Finn A; Cellular and Molecular Medicine Biomedical Sciences Building, University of Bristol Bristol UK.; Population Health Sciences University of Bristol Bristol UK.; Bristol Vaccine Centre University of Bristol Bristol UK., Toye AM; Bristol Institute for Transfusion Sciences (BITS) NHSBT, Filton Bristol UK.; NIHR Blood and Transplant Research Unit in Red Cell Products Bristol UK.; School of Biochemistry Biomedical Sciences Building University of Bristol Bristol UK., Anstee DJ; Bristol Institute for Transfusion Sciences (BITS) NHSBT, Filton Bristol UK.; NIHR Blood and Transplant Research Unit in Red Cell Products Bristol UK.; School of Biochemistry Biomedical Sciences Building University of Bristol Bristol UK.

Publikováno v: EJHaem [EJHaem] 2021 May; Vol. 2 (2), pp. 175-187. Date of Electronic Publication: 2021 Apr 02.

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Akademický článek

Non-muscle myosin II drives vesicle loss during human reticulocyte maturation.

Autor: Moura PL; School of Biochemistry, University of Bristol, UK., Hawley BR; School of Biochemistry, University of Bristol, UK., Mankelow TJ; Bristol Institute for Transfusion Sciences, National Health Service Blood and Transplant (NHSBT), UK.; NIHR Blood and Transplant Research Unit, University of Bristol, UK., Griffiths RE; Bristol Institute for Transfusion Sciences, National Health Service Blood and Transplant (NHSBT), UK.; NIHR Blood and Transplant Research Unit, University of Bristol, UK.; UQ-StemCARE, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Australia., Dobbe JGG; Department of Biomedical Engineering and Physics, Academic Medical Center, University of Amsterdam, the Netherlands., Streekstra GJ; Department of Biomedical Engineering and Physics, Academic Medical Center, University of Amsterdam, the Netherlands., Anstee DJ; Bristol Institute for Transfusion Sciences, National Health Service Blood and Transplant (NHSBT), UK.; NIHR Blood and Transplant Research Unit, University of Bristol, UK., Satchwell TJ; School of Biochemistry, University of Bristol, UK t.satchwell@bristol.ac.uk ash.m.toye@bristol.ac.uk.; Bristol Institute for Transfusion Sciences, National Health Service Blood and Transplant (NHSBT), UK.; NIHR Blood and Transplant Research Unit, University of Bristol, UK., Toye AM; School of Biochemistry, University of Bristol, UK t.satchwell@bristol.ac.uk ash.m.toye@bristol.ac.uk.; Bristol Institute for Transfusion Sciences, National Health Service Blood and Transplant (NHSBT), UK.; NIHR Blood and Transplant Research Unit, University of Bristol, UK.

Publikováno v: Haematologica [Haematologica] 2018 Dec; Vol. 103 (12), pp. 1997-2007. Date of Electronic Publication: 2018 Aug 03.

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