Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Manjyot K. Nanhwan"'
Autor:
Sven Nylander, Yochai Birnbaum, Gilad D. Birnbaum, Yumei Ye, Jose R. Perez-Polo, Manjyot K. Nanhwan
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35:1805-1814
Objective— In addition to P2Y 12 receptor antagonism, ticagrelor inhibits adenosine cell uptake. Prior data show that 7-day pretreatment with ticagrelor limits infarct size. We explored the acute effects of ticagrelor and clopidogrel on infarct siz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d652c779b037eb92e1d5cafb28cf1f7
https://doi.org/10.1161/atvbaha.115.305655
https://doi.org/10.1161/atvbaha.115.305655
Autor:
Jinqiao Qian, Mandeep Bajaj, Yan Chen, Manjyot K. Nanhwan, Yumei Ye, Yochai Birnbaum, Hongmei Chen
Publikováno v:
Diabetes & Vascular Disease Research
Purpose:To assess the effects of Aleglitazar on hyperglycaemia-induced apoptosis.Methods:We incubated human cardiomyocytes, cardiomyocytes from cardiac-specific peroxisome proliferator-activated receptor-γ knockout or wild-type mice in normoglycaemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880af3ac74ba4b3a5daa93d4c5b5fefd
https://pubmed.ncbi.nlm.nih.gov/28111985
https://pubmed.ncbi.nlm.nih.gov/28111985
Autor:
Manjyot K. Nanhwan, Yumei Ye, Shukuan Ling, Monica Kodakandla, Yochai Birnbaum, Sven Nylander
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34:2078-2085
Objective— In a phase III clinical trial (PLATelet inhibition and patient Outcomes, PLATO), ticagrelor provided better clinical outcomes than clopidogrel in patients with acute coronary syndromes. In addition to P2Y 12 -receptor antagonism, ticagre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb09fbe39db95f27f0364de18754bbc4
https://doi.org/10.1161/atvbaha.114.304002
https://doi.org/10.1161/atvbaha.114.304002
Publikováno v:
Cellular Signalling. 25:2840-2847
Both HIF1α (hypoxia-inducible factor alpha) and VEGF (vascular endothelial growth factor) are implicated in the pathogenesis of diabetic retinopathy (DR). Competitive endogenous RNAs (ceRNAs) are messenger RNA (mRNA) molecules that affect each other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ffe4e8c291b6fc6f18dbda92d6ad35
https://doi.org/10.1016/j.cellsig.2013.08.039
https://doi.org/10.1016/j.cellsig.2013.08.039
Publikováno v:
Cardiovascular drugs and therapy. 30(2)
To evaluate whether aleglitazar (Ale), a dual PPARα/γ agonist, has additive effects on myocardial protection against ischemia-reperfusion injury. Human cardiomyocytes (HCMs), cardiomyocytes from cardiac-specific PPARγ knockout (MCM-PPARγ CKO ) or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f65ea0076cd0394199dde4bfed8f0caf
https://pubmed.ncbi.nlm.nih.gov/26861490
https://pubmed.ncbi.nlm.nih.gov/26861490
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35
Background: Clopidogrel (C) and Ticagrelor (T) are P2Y12 ADP receptor antagonists. In addition, ticagrelor inhibits adenosine cell uptake. In PLATO trial T reduced the incidence of the primary composite endpoint myocardial infarction, stroke or cardi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::274207582b0ddc6a596648089d0eb651
https://doi.org/10.1161/atvb.35.suppl_1.177
https://doi.org/10.1161/atvb.35.suppl_1.177
Autor:
Yochai Birnbaum, Mandeep Bajaj, Shukuan Ling, Manjyot K. Nanhwan, Jose R. Perez-Polo, Yumei Ye
Publikováno v:
Cardiovascular drugs and therapy. 28(5)
Statins increase the incidence of new onset diabetes. Prolonged statin therapy upregulates PTEN expression. PTEN levels are also elevated in diabetic animals. Activation of protein kinase A by cAMP decreases PTEN expression. We assessed whether prolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57e0d563995e5c589d53609d938999cf
https://pubmed.ncbi.nlm.nih.gov/25178970
https://pubmed.ncbi.nlm.nih.gov/25178970
Autor:
Hongju Liu, Alexander C. Castillo, Shukuan Ling, Monica Kodakandla, Bejoy Thomas, Manjyot K. Nanhwan, Jinqiao Qian, Yumei Ye
Publikováno v:
Journal of molecular and cellular cardiology. 65
Background Dysregulation of microRNAs (miRNAs) in arterial dysfunction and hypertension has not been extensively investigated yet. This project determined the effects of two anti-hypertensive β1 adrenergic selective blockers on miRNA expression in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea966459eefcbd538f9aa213c15a928
https://pubmed.ncbi.nlm.nih.gov/24161401
https://pubmed.ncbi.nlm.nih.gov/24161401
Autor:
Yinghui Li, Yu Li, Mandeep Bajaj, Bejoy Thomas, Yochai Birnbaum, Manjyot K. Nanhwan, Shukuan Ling, Yumei Ye
Publikováno v:
Basic Research in Cardiology. 108
Competitive endogenous RNAs (ceRNAs) regulate mRNA transcripts containing common microRNA (miRNA) recognition elements (MREs) through sequestration of shared miRNAs. Interactions of ceRNA have been demonstrated in cancerous cells. However, a paucity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a7cad6323b16d0ed29f0fe2263a5586
https://doi.org/10.1007/s00395-013-0352-2
https://doi.org/10.1007/s00395-013-0352-2
Publikováno v:
Journal of the American College of Cardiology. (12):A22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffa2eaf34167e9d733da807a22cf5406