Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Manjusri Das"'
Autor:
Jaganmay Sarkar, Manjusri Das, Md Sariful Islam Howlader, Prateeksha Prateeksha, Derek Barthels, Hiranmoy Das
Publikováno v:
Cell Death and Disease, Vol 13, Iss 10, Pp 1-12 (2022)
Abstract A natural plant product, epigallocatechin-3-gallate (EGCG), was evaluated for its effectiveness in the regulation of osteoclastogenesis. We found that EGCG inhibited the osteoclast (OC) differentiation in vitro, and in primary bone marrow ce
Externí odkaz:
https://doaj.org/article/98c304af32704601a12b43b6a28b2dca
Autor:
Katie A. Thies, Matthew W. Cole, Rachel E. Schafer, Jonathan M. Spehar, Dillon S. Richardson, Sarah A. Steck, Manjusri Das, Arthur W. Lian, Alo Ray, Reena Shakya, Sue E. Knoblaugh, Cynthia D. Timmers, Michael C. Ostrowski, Arnab Chakravarti, Gina M. Sizemore, Steven T. Sizemore
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-17 (2021)
Abstract Background Breast cancer (BC) is the most common cancer in women and the leading cause of cancer-associated mortality in women. In particular, triple-negative BC (TNBC) has the highest rate of mortality due in large part to the lack of targe
Externí odkaz:
https://doaj.org/article/986a2f2be5dc406fa9d8fb78e612f5b5
Autor:
Gina M. Sizemore, Subhasree Balakrishnan, Katie A. Thies, Anisha M. Hammer, Steven T. Sizemore, Anthony J. Trimboli, Maria C. Cuitiño, Sarah A. Steck, Gary Tozbikian, Raleigh D. Kladney, Neelam Shinde, Manjusri Das, Dongju Park, Sarmila Majumder, Shiva Krishnan, Lianbo Yu, Soledad A. Fernandez, Arnab Chakravarti, Peter G. Shields, Julia R. White, Lisa D. Yee, Thomas J. Rosol, Thomas Ludwig, Morag Park, Gustavo Leone, Michael C. Ostrowski
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
The tumor microenvironment influences tumor progression. Here the authors show that lack of stromal PTEN phosphatase induces DNA repair defects in the neighboring mammary gland epithelial cells via hyperactivation of EGF-receptor signaling, resulting
Externí odkaz:
https://doaj.org/article/f4113fd816a74125b1e376f6cb322dab
Autor:
Elshafa Hassan Ahmed, Eric Brooks, Shelby Sloan, Sarah Schlotter, Frankie Jeney, Claire Hale, Charlene Mao, Xiaoli Zhang, Eric McLaughlin, Polina Shindiapina, Salma Shire, Manjusri Das, Alexander Prouty, Gerard Lozanski, Admasu T. Mamuye, Tamrat Abebe, Lapo Alinari, Michael A. Caligiuri, Robert A. Baiocchi
Publikováno v:
Vaccines, Vol 9, Iss 6, p 555 (2021)
Epstein-Barr virus (EBV) is a human herpes virus that infects over 90% of the world’s population and is linked to development of cancer. In immune-competent individuals, EBV infection is mitigated by a highly efficient virus-specific memory T-cell
Externí odkaz:
https://doaj.org/article/828fbf3e9e194f9d91f553e02a899a15
Autor:
Manjusri Das, Moonmoon Deb, Dipranjan Laha, Matthew Joseph, Suman Kanji, Reeva Aggarwal, O. Hans Iwenofu, Vincent J. Pompili, Wael Jarjour, Hiranmoy Das
Publikováno v:
Cells, Vol 8, Iss 8, p 908 (2019)
Rheumatoid arthritis (RA) is an immune-mediated inflammatory disease, and Krüppel-like factor 2 (KLF2) regulates immune cell activation and function. Herein, we show that in our experiments 50% global deficiency of KLF2 significantly elevated arthri
Externí odkaz:
https://doaj.org/article/aae594af504b4028b9a435a8384486c1
Autor:
Suman Kanji, Manjusri Das, Reeva Aggarwal, Jingwei Lu, Matthew Joseph, Sujit Basu, Vincent J. Pompili, Hiranmoy Das
Publikováno v:
Stem Cell Research, Vol 12, Iss 1, Pp 275-288 (2014)
Nanofiber-expanded human umbilical cord blood-derived CD34+ cell therapy is under consideration for treating peripheral and cardiac ischemia. However, the therapeutic efficacy of nanofiber-expanded human umbilical cord blood-derived (NEHUCB) CD34+ ce
Externí odkaz:
https://doaj.org/article/88454234a1114d3fa19733437809046f
Autor:
Hiranmoy Das, Zhihui Wang, M. Khalid Khan Niazi, Reeva Aggarwal, Jingwei Lu, Suman Kanji, Manjusri Das, Matthew Joseph, Metin Gurcan, Vittorio Cristini
Publikováno v:
PLoS ONE, Vol 8, Iss 10 (2013)
Externí odkaz:
https://doaj.org/article/b4da51b64c92458e98ab464250ebc51f
Autor:
Hiranmoy Das, Zhihui Wang, M Khalid Khan Niazi, Reeva Aggarwal, Jingwei Lu, Suman Kanji, Manjusri Das, Matthew Joseph, Metin Gurcan, Vittorio Cristini
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61398 (2013)
Molecular-focused cancer therapies, e.g., molecularly targeted therapy and immunotherapy, so far demonstrate only limited efficacy in cancer patients. We hypothesize that underestimating the role of biophysical factors that impact the delivery of dru
Externí odkaz:
https://doaj.org/article/3fd9990d60db45289ed8bd558d7833ed
Autor:
Reeva Aggarwal, Jingwei Lu, Suman Kanji, Matthew Joseph, Manjusri Das, Garrett J Noble, Brooke K McMichael, Sudha Agarwal, Richard T Hart, Zongyang Sun, Beth S Lee, Thomas J Rosol, Rebecca Jackson, Hai-Quan Mao, Vincent J Pompili, Hiranmoy Das
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39365 (2012)
Osteoporosis is a bone disorder associated with loss of bone mineral density and micro architecture. A balance of osteoblasts and osteoclasts activities maintains bone homeostasis. Increased bone loss due to increased osteoclast and decreased osteobl
Externí odkaz:
https://doaj.org/article/9dc52b2d97a744c4b519d68f6ef9356c
Autor:
Jingwei Lu, Reeva Aggarwal, Suman Kanji, Manjusri Das, Matthew Joseph, Vincent Pompili, Hiranmoy Das
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e23348 (2011)
Mechanisms of human Vγ2Vδ2 T cell-mediated tumor immunity have yet to be fully elucidated.At least some tumor cell recognition is mediated by NKG2D-MICA interactions. Herein, by using MTT assay and PI-BrdU co-staining and Western-blot, we show that
Externí odkaz:
https://doaj.org/article/b6ff38ede5c94b9ca1e5f26d76f47153