Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Manjunatha K. Nanjappa"'
Autor:
Siddaraju V. Boregowda, Manjunatha K. Nanjappa, Cori N. Booker, Jacqueline Strivelli, Valentina M. Supper, Paul S. Cooke, Donald G. Phinney
Publikováno v:
Biology, Vol 11, Iss 9, p 1257 (2022)
Obesity and type II diabetes mellitus (T2DM) are prominent risk factors for secondary osteoporosis due to the negative impacts of hyperglycemia and excessive body fat on bone metabolism. While the armamentarium of anti-diabetic drugs is expanding, th
Externí odkaz:
https://doaj.org/article/13aa00ddf3634da2bc2ba99743a7517f
Publikováno v:
Asian Journal of Andrology, Vol 17, Iss 3, Pp 355-359 (2015)
There have been significant breakthroughs over the past decade in the development and use of pluripotent stem cells as a potential source of cells for applications in regenerative medicine. It is likely that this methodology will begin to play an imp
Externí odkaz:
https://doaj.org/article/f6d9a245683248e58bf421b2b879ce2a
Autor:
Duolin Wang, Manjunatha K. Nanjappa, Jiude Mao, Paul S. Cooke, Theresa I. Medrano, Jessica A. Kinkade, Yang Liu, Zhen Lyu, Trupti Joshi, Cheryl S. Rosenfeld, Sergei G. Tevosian, Fahong Yu, Ana M Mesa
Publikováno v:
Physiol Genomics
Enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase that suppresses gene expression. Previously, we developed a conditional null model where EZH2 is knocked out in uterus. Deletion of uterine EZH2 increased proliferation of luminal and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da6a18c7032c2940d963bedc0aa86a5
https://doi.org/10.1152/physiolgenomics.00098.2019
https://doi.org/10.1152/physiolgenomics.00098.2019
Autor:
Paul S Cooke, Manjunatha K Nanjappa
Publikováno v:
Asian Journal of Andrology, Vol 19, Iss 1, Pp 3-4 (2017)
Externí odkaz:
https://doaj.org/article/21ad5286dee74d4ba402d0eed5eabe11
Autor:
Jianrong Wang, Bryce D Warren, Kathryn Brittain, Gustavo Blanco, Soo Hyun Ahn, Paul S. Cooke, Gladis Sánchez, Manjunatha K. Nanjappa, Brian K. Petroff, Hao Wang, Yong Fan, Margaret G. Petroff
Publikováno v:
Am J Pathol
Male factors, including those of autoimmune origin, contribute to approximately 50% of infertility cases in humans. However, the mechanisms underlying autoimmune male infertility are poorly understood. Deficiency in autoimmune regulator (AIRE) impair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d2ce6560d00da075eaa1b0598f81062
https://europepmc.org/articles/PMC8420865/
https://europepmc.org/articles/PMC8420865/
Autor:
Ellis R. Levin, Theresa I. Medrano, Jiude Mao, Paul S. Cooke, Cheryl S. Rosenfeld, Paul D. Caldo, Ana M Mesa, Madison T. Ortega, Manjunatha K. Nanjappa, Jessica A. Kinkade
Publikováno v:
Biol Reprod
Biology of reproduction, vol 101, iss 2
Biology of reproduction, vol 101, iss 2
Both membrane and nuclear fractions of estrogen receptor 1 (ESR1) mediate 17β-estradiol (E2) actions. Mice expressing nuclear (n)ESR1 but lacking membrane (m)ESR1 (nuclear-only estrogen receptor 1 [NOER] mice) show reduced E2 responsivity and reprod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7acb6281ba6c9d53b4e0efa8b51a10f4
https://doi.org/10.1093/biolre/ioz090
https://doi.org/10.1093/biolre/ioz090
Autor:
Paul S Cooke, Manjunatha K Nanjappa
Publikováno v:
Asian Journal of Andrology, Vol 17, Iss 3, Pp 441-442 (2015)
How the primordial germ cell (PGC) lineage, which eventually gives rise to spermatozoa in males and oocytes in females, is established in the developing mammalian embryo has been a critical topic in both developmental and reproductive biology for man
Externí odkaz:
https://doaj.org/article/b867251af02e4ef8863e4cdfbbe067de
Autor:
Gail S. Prins, Manjunatha K. Nanjappa, Theresa I. Medrano, Paul S. Cooke, Barry R. Zirkin, Haolin Chen
Publikováno v:
Andrology. 5:1165-1173
Summary Stem Leydig cells (SLCs), precursors of testicular Leydig cells that secrete testosterone required for male sexual differentiation, spermatogenesis, and fertility, were recently identified in rat testes. Various types of stem cells have shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5085c8c73154345536b6138b374c9d5f
https://doi.org/10.1111/andr.12415
https://doi.org/10.1111/andr.12415
Publikováno v:
Physiological Reviews. 97:995-1043
Estrogens have historically been associated with female reproduction, but work over the last two decades established that estrogens and their main nuclear receptors (ESR1 and ESR2) and G protein-coupled estrogen receptor (GPER) also regulate male rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::132184c84ce685f78e3928face52c3ca
https://doi.org/10.1152/physrev.00018.2016
https://doi.org/10.1152/physrev.00018.2016
Autor:
Theresa I. Medrano, Francesco J. DeMayo, John P. Lydon, Ellis R. Levin, Ana M Mesa, Wendy N. Jefferson, Carmen J. Williams, Manjunatha K. Nanjappa, Paul S. Cooke
Publikováno v:
Biology of reproduction, vol 101, iss 2
Biol Reprod
Biol Reprod
Enhancer of zeste homolog 2 (EZH2) is a rate-limiting catalytic subunit of a histone methyltransferase, polycomb repressive complex, which silences gene activity through the repressive histone mark H3K27me3. EZH2 is critical for epigenetic effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357e14628864a0bef761f7882e1d7b11
https://escholarship.org/uc/item/6ft5b9bx
https://escholarship.org/uc/item/6ft5b9bx