Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Manjunath P Pai"'
Autor:
Rachel O’Connell, Manjunath P Pai
Publikováno v:
Trauma Surgery & Acute Care Open, Vol 6, Iss 1 (2021)
Background Intraosseous (IO) drug delivery may be necessary in emergency situations when intravenous access is unattainable. Valproic acid (VPA) is a histone deacetylase inhibitor that has previously been shown to improve survival in preclinical mode
Externí odkaz:
https://doaj.org/article/04f8a3f642174ee7b34b70f2d98fc489
Autor:
Valerie J Morley, Clare L Kinnear, Derek G Sim, Samantha N Olson, Lindsey M Jackson, Elsa Hansen, Grace A Usher, Scott A Showalter, Manjunath P Pai, Robert J Woods, Andrew F Read
Publikováno v:
eLife, Vol 9 (2020)
A key challenge in antibiotic stewardship is figuring out how to use antibiotics therapeutically without promoting the evolution of antibiotic resistance. Here, we demonstrate proof of concept for an adjunctive therapy that allows intravenous antibio
Externí odkaz:
https://doaj.org/article/a1a0ef55660049aaa1bfa3ba8c496de1
Autor:
Zhuo Ma, Erica Lasek-Nesselquist, Jackson Lu, Ryan Schneider, Riddhi Shah, George Oliva, Janice Pata, Kathleen McDonough, Manjunath P Pai, Warren E Rose, George Sakoulas, Meenakshi Malik
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0198366 (2018)
The extensive use of daptomycin (DAP) for treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections in the last decade has led to the emergence of DAP non-susceptible (DNS) Staphylococcus aureus strains. A better understanding of the
Externí odkaz:
https://doaj.org/article/9c9aede5faf84f6b9f922e3954d84f23
Publikováno v:
Therapeutic Drug Monitoring. 45:95-101
Publikováno v:
Bioanalysis. 14(17)
Background: Volumetric absorptive microsampling may reduce the blood collection burden associated with therapeutic drug monitoring of immunosuppression to prevent organ transplant rejection. This work describes the development of a laboratory and ana
Publikováno v:
British Journal of Clinical Pharmacology. 89:1207-1210
The goal of this study was to use a model kidney function clearance-dependent drug (vancomycin) to understand the gain or loss of precision in dosing with use of serum creatinine (S
Publikováno v:
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 43:35-42
The use of race in medicine can contribute to health inequity. Updated equations for estimated glomerular filtration rate (eGFR) without race have been published. Likewise, de-indexation of eGFR to body surface area (BSA) has been recommended by regu
Autor:
Manjunath P Pai, Pier Giorgio Cojutti, Valentina Gerussi, Paola Della Siega, Carlo Tascini, Federico Pea
Publikováno v:
Clinical Infectious Diseases. 76:1173-1179
Background Linezolid-induced myelosuppression limits optimal therapy in cardiosurgical patients with deep-seated infections at current doses. Methods Adult patients who received a cardiac surgery intervention and linezolid for a documented or presume
Autor:
Sirima, Sitaruno, Wichai, Santimaleeworagun, Sutthiporn, Pattharachayakul, Kenneth C, DeBacker, Veerapong, Vattanavanit, Wanrada, Binyala, Manjunath P, Pai
Publikováno v:
The Journal of Clinical Pharmacology. 62:1215-1226
Empiric antibiotic dosing frequently relies on an estimate of kidney function based on age, serum creatinine, sex, and race (on occasion). New non-race-based estimated glomerular filtration rate (eGFR) equations have been published, but their role in
Autor:
N. Lynn Henry, Ellen M. Lavoie Smith, Daniel F. Hayes, Catherine Van Poznak, Anne F. Schott, Jennifer J. Griggs, Monika Burness, Manjunath P. Pai, Feng Li, Kiran Vangipuram, Kelley M. Kidwell, Daniel L. Hertz
Supplementary Figure 2: Paclitaxel Exposure in Patients Who Did or Did Not Experience Peripheral Neuropathy-Induced Treatment Disruption. Patients who experienced PN-induced treatment disruption had greater median paclitaxel Tc>0.05 than patients who
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bca13a1e7c23aeff4c603d4b99cf0ff
https://doi.org/10.1158/1078-0432.22469955
https://doi.org/10.1158/1078-0432.22469955