Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Manjun Li"'
Autor:
Melissa K. Bennett, Manjun Li, Melinda N. Tea, Melissa R. Pitman, John Toubia, Paul P.-S. Wang, Dovile Anderson, Darren J. Creek, Robert Z. Orlowski, Briony L. Gliddon, Jason A. Powell, Craig T. Wallington-Beddoe, Stuart M. Pitson
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 24, Iss 1, Pp 1-11 (2022)
The introduction of the proteasome inhibitor bortezomib into treatment regimens for myeloma has led to substantial improvement in patient survival. However, whilst bortezomib elicits initial responses in many myeloma patients, this haematological mal
Externí odkaz:
https://doaj.org/article/f5e0bdd9d3004cfdbf70bbe296a47fe3
Autor:
Li Yang, Manjun Li, Fang Wang, Chen Zhen, Min Luo, Xiaona Fang, Hong Zhang, Jianye Zhang, Qingshan Li, Liwu Fu
Publikováno v:
Cellular Physiology and Biochemistry, Vol 46, Iss 6, Pp 2487-2499 (2018)
Background/Aims: Multidrug resistance (MDR) triggered by ATP binding cassette (ABC) transporters, such as ABCB1, ABCC1, and ABCG2, is a key obstacle for successful cancer chemotherapy. There is currently no FDA-approved MDR modulator that can be used
Externí odkaz:
https://doaj.org/article/890ab6ad65c64262b22d3d4df4a4de20
Publikováno v:
Structures. 53:199-204
Publikováno v:
Structures. 48:1722-1729
Autor:
Briony L. Gliddon, Craig T. Wallington-Beddoe, Manjun Li, Darren J. Creek, Melissa R. Pitman, Melinda N. Tea, Paul Wang, Dovile Anderson, John Toubia, Melissa K. Bennett, Robert Z. Orlowski, Stuart M. Pitson, Jason A. Powell
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 24, Iss 1, Pp 1-11 (2022)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
Refereed/Peer-reviewed The introduction of the proteasome inhibitor bortezomib into treatment regimens for myeloma has led to substantial improvement in patient survival. However, whilst bortezomib elicits initial responses in many myeloma patients,
Publikováno v:
REVIEWS ON ADVANCED MATERIALS SCIENCE. 61:350-362
Two-component foaming polymer (TFPU) grouting material is increasingly used in civil engineering. Its compressive strength is key to achieving the desired enhancing effect. The constitutive model of TFPU grouting material is a theoretical basis to ev
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 147:691-701
Some chemotherapy drugs have immunomodulatory effects on specific tumors. The potential of vincristine (VCR) in the R-CHOP regimen to act as both a chemotherapeutic and an immunomodulatory agent via PD-L1 in tumor cells remains unclear. In vitro scre
Autor:
Mengzhen Yue, Lijian Shao, Qingxian Zhu, Rui Xu, Wuping Yang, Jiaoqi Cheng, Xincheng Wu, Huihong Zeng, Manjun Li, Huan Li, Ying Fan, Jiahui Tang, Guangqin Fan, Hongping Chen, Bohai Kuang
Publikováno v:
Br J Pharmacol
Background and purpose Damage to intestinal epithelial cells and mucosa limits the effectiveness of several anti-cancer chemotherapeutic agents but the underlying mechanism (s) remain unknown. Little is known of how enteric nervous system regulates p
Autor:
Abel Tesfaye Anshabo, Laychiluh Bantie, Sarah Diab, Jimma Lenjisa, Alemwork Kebede, Yi Long, Gary Heinemann, Jasmine Karanjia, Benjamin Noll, Sunita K. C. Basnet, Manjun Li, Robert Milne, Hugo Albrecht, Shudong Wang
Publikováno v:
Cancers; Volume 14; Issue 5; Pages: 1113
Mutations in FMS-like tyrosine kinase 3 (FLT3) occur in approximately one-third of AML patients and are associated with a particularly poor prognosis. The most common mutation, FLT3-ITD, is a self-activating internal tandem duplication (ITD) in the F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb76e0b4e5a2ac45bd74644f460d73c1
https://hdl.handle.net/11541.2/31432
https://hdl.handle.net/11541.2/31432
Autor:
Alexander C. Lewis, Victoria S. Pope, Melinda N. Tea, Manjun Li, Gus O. Nwosu, Thao M. Nguyen, Craig T. Wallington-Beddoe, Paul A. B. Moretti, Dovile Anderson, Darren J. Creek, Maurizio Costabile, Saira R. Ali, Chloe A. L. Thompson-Peach, B. Kate Dredge, Andrew G. Bert, Gregory J. Goodall, Paul G. Ekert, Anna L. Brown, Richard D’Andrea, Nirmal Robinson, Melissa R. Pitman, Daniel Thomas, David M. Ross, Briony L. Gliddon, Jason A. Powell, Stuart M. Pitson
Inducing cell death by the sphingolipid ceramide is a potential anticancer strategy, but the underlying mechanisms remain poorly defined. In this study, triggering an accumulation of ceramide in acute myeloid leukemia (AML) cells by inhibition of sph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ed8fbe2daf653ebbee791ab6b83276b
https://hdl.handle.net/11541.2/31406
https://hdl.handle.net/11541.2/31406