Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Manjula Viggeswarapu"'
Autor:
Joseph L. Roberts, Mingcan Yu, Manjula Viggeswarapu, Jamie L. Arnst, Roberto Pacifici, George R. Beck Jr
Publikováno v:
JCI Insight, Vol 8, Iss 10 (2023)
The intake of dietary phosphate far exceeds recommended levels; however, the long-term health consequences remain relatively unknown. Here, the chronic physiological response to sustained elevated and reduced dietary phosphate consumption was investi
Externí odkaz:
https://doaj.org/article/ad4a4086c828464eac336155a4505759
Bioactive effects of silica nanoparticles on bone cells are size, surface, and composition dependent
Publikováno v:
Acta Biomater
Silica based nanoparticles have been demonstrated to have intrinsic biologic activity towards the skeleton and to function by promoting the differentiation of bone forming osteoblasts while inhibiting the differentiation of bone resorbing osteoclasts
Autor:
George R. Beck, Anna K. Porter, Manjula Viggeswarapu, Joseph L. Roberts, Orlando M. Gutiérrez
Publikováno v:
J Nutr Biochem
Phosphorus is a common additive used in food processing that is typically consumed in excess of the recommended daily allowance; however, our knowledge of its effects on health, in the context of normal renal function, is limited. Unlike phosphorus,
Publikováno v:
Footankle international. 39(8)
Background:Vancomycin is frequently applied locally to the operative site during foot and ankle procedures to help prevent infection. Although the efficacy of locally applied vancomycin has been demonstrated in spine surgery, there is no consensus on
Autor:
Colleen Oliver, Mesfin Teklemariam, Sreedhara Sangadala, Louisa Titus, Scott D. Boden, Matthew F. Gary, Manjula Viggeswarapu
Publikováno v:
Neurosurgery. 61:182-186
Autor:
Scott D. Boden, Louisa Titus, Yunshan Liu, Motohiro Okada, Sreedhara Sangadala, Manjula Viggeswarapu
Publikováno v:
Protein Expression and Purification. 65:165-173
Short peptide sequences known as protein transduction domains have become increasingly prevalent as tools to internalize molecules that would otherwise remain extracellular. Here, we determine whether a purified recombinant mammalian intracellular os
Autor:
Qinming Fei, Sreedhara Sangadala, Manjula Viggeswarapu, Scott D. Boden, Yunshan Liu, Louisa Titus
Publikováno v:
Acta Biochimica et Biophysica Sinica. 39:693-700
LIM mineralization protein-1 (LMP-1) is a novel intracellular osteoinductive protein that has been shown to induce bone formation both in vitro and in vivo. LMP-1 contains an N-terminal PDZ domain and three C-terminal LIM domains. In this study, we i
Publikováno v:
Journal of Bone and Mineral Research. 17:406-414
Rat LIM mineralization protein 1 (LMP-1, an LIM domain protein) mediates bone morphogenetic protein 6 (BMP-6) induction of bone nodule formation in fetal rat calvarial osteoblast (ROB) cultures. We have isolated the complementary DNA (cDNA) for the h
Autor:
John Louis-Ugbo, Gregory A. Hair, Hak Sun Kim, Matthew T. Mayr, Manjula Viggeswarapu, William C. Hutton, Hideki Murakami, Yunshan Liu, Scott D. Boden, Louisa Titus
Publikováno v:
The Journal of Bone and Joint Surgery-American Volume. 83:364-376
Background: The LIM mineralization protein-1 (LMP-1) gene encodes for an intracellular protein that induces the expression of several bone growth factors. The purpose of the present study was to determine the feasibility and the optimal dose of adeno
Publikováno v:
Clinical Orthopaedics and Related Research. 379:S225-S233
Spine fusion is a commonly performed yet often unsuccessful surgical procedure. As many as 40% of patients undergoing spine fusion may have a nonunion or failure to form a continuous bone bridge. This clinical challenge has focused much of the attent