Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Manjula, Nandakumar"'
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1137 (2024)
Introduction: Hypoglycemia has been associated with cardiovascular events, and glucose variability has been suggested to be associated with increased cardiovascular risk. Therefore, in this study, we examined the effect on proteomic cardiovascular ri
Externí odkaz:
https://doaj.org/article/177450f86d4744b4836a4b39eb5fe2e8
Autor:
Abu Saleh Md Moin, Manjula Nandakumar, Ilhame Diboun, Ahmed Al-Qaissi, Thozhukat Sathyapalan, Stephen L. Atkin, Alexandra E. Butler
Publikováno v:
Atherosclerosis Plus, Vol 46, Iss , Pp 35-45 (2021)
Background and aims: An association between hypoglycaemia and adverse cardiovascular events has been suggested from longitudinal and retrospective cohort studies. The complement pathway proteins in hypoglycemia are not well studied. Here, we hypothes
Externí odkaz:
https://doaj.org/article/cb63b8066a2148b4841186580d9202e7
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 2044 (2023)
Introduction. Oxidative stress (OS) is recognized in the pathophysiology of polycystic ovary syndrome (PCOS). OS results in intracellular reactive oxygen species generation, causing oxidative protein damage that is protected by heat shock proteins (H
Externí odkaz:
https://doaj.org/article/f4f984d2d52f41d88e833eb0cde02399
Autor:
Alexander S. Atkin, Abu Saleh Md Moin, Manjula Nandakumar, Ahmed Al-Qaissi, Thozhukat Sathyapalan, Stephen L. Atkin, Alexandra E. Butler
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Heat shock proteins contribute to diabetes-induced complications and are affected by glycemic control. Our hypothesis was that hypoglycemia-induced heat shock and related protein changes would be amplified in type 2 diabetes (T2D). This pros
Externí odkaz:
https://doaj.org/article/a5987cfffa694d3688bc0a2df912dfef
Autor:
Edwina Brennan, Alexandra E. Butler, Manjula Nandakumar, Daniel S. Drage, Thozhukat Sathyapalan, Stephen L. Atkin
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1451 (2023)
In human population studies, organochlorine pesticides (OCPs) have been linked to vitamin D deficiency. Therefore, this study examined the association between OCPs, vitamin D3 (cholecalciferol, 25(OH)D3), and the active metabolite 1,25-dihydrovitamin
Externí odkaz:
https://doaj.org/article/7afd995bd0f7460fb7e4080ffcb48bdb
Autor:
Abu Saleh Md Moin, Manjula Nandakumar, Thozhukat Sathyapalan, Stephen L. Atkin, Alexandra E. Butler
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-4 (2021)
Externí odkaz:
https://doaj.org/article/fdcde42d035649a78a66480aa8956895
Autor:
Abu Saleh Md Moin, Manjula Nandakumar, Ahmed Al-Qaissi, Thozhukat Sathyapalan, Stephen L. Atkin, Alexandra E. Butler
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Background and Purpose: Patients with type 2 diabetes (T2D) have increased risk of cardiovascular disease (CVD), encompassing myocardial infarction, stroke, and peripheral vascular disease. We hypothesized that those biomarkers indicative of acute is
Externí odkaz:
https://doaj.org/article/e95c31b9554649eaaaa91e1455efafca
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Type 1 diabetes (T1D) is a T-cell mediated autoimmune disease characterized by recognition of pancreatic β-cell proteins as self-antigens, called autoantigens (AAgs), followed by loss of pancreatic β-cells. (Pre-)proinsulin ([P]PI), glutamic acid d
Externí odkaz:
https://doaj.org/article/e5f1d9f275f74aa1944559f9db084e57
Autor:
Abu Saleh Md Moin, Manjula Nandakumar, Hassan Kahal, Thozhukat Sathyapalan, Stephen L. Atkin, Alexandra E. Butler
Publikováno v:
Cells, Vol 10, Iss 11, p 3109 (2021)
Mild hypoglycemia is common in clinical practice. Severe hypoglycemia results in heat shock protein and associate co-chaperone changes. Whether mild prolonged hypoglycemia elicits a similar response with inflammatory and oxidative-stress responses co
Externí odkaz:
https://doaj.org/article/8317ded7de7842c79ac199c7b013c737
Autor:
Ahmed Al-Qaissi, Stephen L. Atkin, Abu Saleh Md Moin, Manjula Nandakumar, Alexandra E. Butler, Thozhukat Sathyapalan, Ilhame Diboun
Publikováno v:
Atherosclerosis Plus, Vol 46, Iss, Pp 35-45 (2021)
Background and aims: An association between hypoglycaemia and adverse cardiovascular events has been suggested from longitudinal and retrospective cohort studies. The complement pathway proteins in hypoglycemia are not well studied. Here, we hypothes