Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Manjul Rana"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Prostate cancer (PCa) is dependent on the androgen receptor (AR). Advanced PCa is treated with an androgen deprivation therapy-based regimen; tumors develop resistance, although they typically remain AR-dependent. Expression of constitutivel
Externí odkaz:
https://doaj.org/article/d596508e4db041fab19ab78aa8fed1fd
Autor:
Manjul Rana, Jianrong Dong, Matthew J. Robertson, Paul Basil, Cristian Coarfa, Nancy L. Weigel
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/a38ab4c701574deab78bca9c62ffb56c
Autor:
Manjul Rana, Rita Kansal, Mehdi Chaib, Bin Teng, Michelle Morrrison, David Neil Hayes, Ansley G. Stanfill, David Shibata, James A. Carson, Liza Makowski, Evan S. Glazer
Publikováno v:
Molecular Carcinogenesis. 61:549-557
Pancreatic ductal adenocarcinoma (PDA) tumors have a highly immunosuppressive desmoplastic tumor microenvironment (TME) where immune checkpoint inhibition (ICI) therapy has been exceptionally ineffective. Transforming growth factor-β (TGF-β) recept
Publikováno v:
Cancer Research. 82:B044-B044
Introduction: The bromodomain and extra-terminal (BET) protein family contains proteins which have evolutionarily conserved bromodomains (BRDs) that specifically recognize acetylated lysine residues on the histone tails of chromatin and regulate gene
Autor:
David Shibata, Manjul Rana, Rita Kansal, Evan S. Glazer, Anders Berglund, Abidemi Ajidahun, Abul Elahi
Publikováno v:
Cancer Research. 81:PO-090
INTRODUCTION: Transforming growth factor-β (TGF-β), a ubiquitous molecule in pancreatic ductal adenocarcinoma (PDA) tumors, acts as a potent inducer of tumor invasion by regulating proteins involved in metastasis and driving epithelial-mesenchymal
Publikováno v:
Cell Biology International. 41:570-576
The Pregnane and Xenobiotic Receptor (PXR; NR1I2) is a ligand-modulated transcription factor that belongs to the nuclear receptor superfamily. It is expressed at higher levels primarily in liver and intestine as compared to the levels in several othe
Autor:
Cristian Coarfa, Matthew J. Robertson, Manjul Rana, Jianrong Dong, Harika Nagandla, Basil Paul, Nancy L. Weigel
Publikováno v:
Journal of the Endocrine Society
The androgen receptor (AR) is a hormone activated transcription factor which is important for the growth and progression of prostate cancer (PCa). Metastatic PCa is treated with androgen deprivation therapy (ADT) based regimen but eventually, these t
Autor:
Paul Basil, Nancy L. Weigel, Cristian Coarfa, Matthew J. Robertson, Manjul Rana, Jianrong Dong
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
Scientific Reports
Scientific Reports
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Publikováno v:
Gastroenterology. 160:S-915
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1859:1183-1197
Pregnane & Xenobiotic Receptor (PXR) acts as a xenosensing transcriptional regulator of many drug metabolizing enzymes and transporters of the 'detoxification machinery' that coordinate in elimination of xenobiotics and endobiotics from the cellular