Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Manju Swaroop"'
Autor:
Holly Y Chen, Manju Swaroop, Samantha Papal, Anupam K Mondal, Hyun Beom Song, Laura Campello, Gregory J Tawa, Florian Regent, Hiroko Shimada, Kunio Nagashima, Natalia de Val, Samuel G Jacobson, Wei Zheng, Anand Swaroop
Publikováno v:
eLife, Vol 12 (2023)
Ciliopathies manifest from sensory abnormalities to syndromic disorders with multi-organ pathologies, with retinal degeneration a highly penetrant phenotype. Photoreceptor cell death is a major cause of incurable blindness in retinal ciliopathies. To
Externí odkaz:
https://doaj.org/article/d7b516710de643d58647394ef7678b1a
Autor:
Holly Y Chen, Manju Swaroop, Samantha Papal, Anupam K Mondal, Hyun Beom Song, Laura Campello, Gregory J Tawa, Florian Regent, Hiroko Shimada, Kunio Nagashima, Natalia de Val, Samuel G Jacobson, Wei Zheng, Anand Swaroop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2140ff55ea36b5c6f2347a8d42639c39
https://doi.org/10.7554/elife.83205.sa2
https://doi.org/10.7554/elife.83205.sa2
Autor:
Holly Y. Chen, Manju Swaroop, Samantha Papal, Anupam K. Mondal, Gregory J. Tawa, Florian Regent, Hiroko Shimada, Kunio Nagashima, Natalia de Val, Samuel G. Jacobson, Wei Zheng, Anand Swaroop
Ciliopathies manifest from sensory abnormalities to syndromic disorders with multiorgan pathologies, with retinal degeneration a highly penetrant phenotype. Photoreceptor cell death is a major cause of incurable blindness in retinal ciliopathies. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fd3da62732e2111ab85d29896c9d453
https://doi.org/10.1101/2022.09.14.22279917
https://doi.org/10.1101/2022.09.14.22279917
Autor:
Manisha Pradhan, Xin Xu, Miao Xu, Zhiji Luo, Manju Swaroop, Qi Zhang, Amy Wang, Lu Chen, Natalie Hagen, Min Shen, Yihong Ye, Juhyung Lee, Wei Zheng, Catherine Z. Chen, Yue Xu, Wenwei Huang, Lihui Wang
Publikováno v:
Cell Discovery, Vol 6, Iss 1, Pp 1-14 (2020)
Cell Discovery
bioRxiv
Cell Discovery
bioRxiv
Drugs capable of blocking the infectious cycle of the coronavirus SARS-CoV-2 are urgently needed to tackle the ongoing COVID-19 pandemic. To this end, the cell entry of SARS-CoV-2, initiated by the binding of the viral Spike (S) protein to human ACE2
Autor:
Abhishek Vats, Gregory J. Tawa, Leah C. Byrne, William L. Seibel, Yuanyuan Chen, Bing Feng, Manju Swaroop, Wei Zheng, Xujie Liu, Mark E. Schurdak, Hong Tang
Publikováno v:
FASEB J
Rhodopsin mutation and misfolding is a common cause of autosomal dominant retinitis pigmentosa. Using a luciferase reporter assay, we undertook a small-molecule high-throughput screening of 68,979 compounds and identified nine compounds that selectiv
Autor:
Junjie Hong, Yu-Shan Cheng, Shu Yang, Manju Swaroop, Miao Xu, Jeanette Beers, Jizhong Zou, Wenwei Huang, Juan J. Marugan, Xiujun Cai, Wei Zheng
Publikováno v:
Exp Cell Res
Mucopolysaccharidosis type II (MPS II), also known as Hunter syndrome, is a rare, lysosomal disorder caused by mutations in a gene encoding iduronate-2-sulfatase (IDS). IDS deficiency results in an accumulation of glycosaminoglycans (GAGs) and second
Publikováno v:
Human Molecular Genetics. 27:3612-3626
Mucopolysaccharidosis type I (MPS I) is caused by deficiency of α-l-iduronidase (IDUA), a lysosomal enzyme involved in the breakdown and recycling of glycosaminoglycans (GAGs). Although enzyme replacement therapy is available, the efficacy of the tr
Publikováno v:
Exp Cell Res
Mucopolysaccharidosis type IIIB (MPS IIIB) is a lysosomal disease caused by mutations in the NAGLU gene encoding α-N-acetylglucosaminidase (NAGLU) which degrades heparan sulfate in lysosomes. Deficiency in NAGLU results in lysosomal accumulation of
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Publikováno v:
Stem Cells Translational Medicine. 4:800-808
Fragile X syndrome (FXS), the most common form of inherited cognitive disability, is caused by a deficiency of the fragile X mental retardation protein (FMRP). In most patients, the absence of FMRP is due to an aberrant transcriptional silencing of t