Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Manju Sasi"'
Autor:
Beatrice Vignoli, Gabriele Sansevero, Manju Sasi, Roberto Rimondini, Robert Blum, Valerio Bonaldo, Emiliano Biasini, Spartaco Santi, Nicoletta Berardi, Bai Lu, Marco Canossa
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-17 (2021)
Beatrice Vignoli et al. examine potential molecular mechanisms of long-term storage information in mice. Their results suggest that astrocytes may help convert neuronal BDNF precursor into active prodomain and mature forms to enhance post-synaptic si
Externí odkaz:
https://doaj.org/article/8f200d647e2d488e9a5707b188533ab9
Autor:
Dennis Segebarth, Matthias Griebel, Nikolai Stein, Cora R von Collenberg, Corinna Martin, Dominik Fiedler, Lucas B Comeras, Anupam Sah, Victoria Schoeffler, Teresa Lüffe, Alexander Dürr, Rohini Gupta, Manju Sasi, Christina Lillesaar, Maren D Lange, Ramon O Tasan, Nicolas Singewald, Hans-Christian Pape, Christoph M Flath, Robert Blum
Publikováno v:
eLife, Vol 9 (2020)
Bioimage analysis of fluorescent labels is widely used in the life sciences. Recent advances in deep learning (DL) allow automating time-consuming manual image analysis processes based on annotated training data. However, manual annotation of fluores
Externí odkaz:
https://doaj.org/article/ac0ffdcd78dc4ad080ed0dc01533019f
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 3, p e1006054 (2018)
Local and spontaneous calcium signals play important roles in neurons and neuronal networks. Spontaneous or cell-autonomous calcium signals may be difficult to assess because they appear in an unpredictable spatiotemporal pattern and in very small ne
Externí odkaz:
https://doaj.org/article/5609e02ac4e4495d938125218976726f
Autor:
Jérémy Signoret-Genest, Marcus Behringer, Nina Schukraft, Markus Sauer, Michael Sendtner, Philip Tovote, Manju Sasi, Stefanie Rauskolb, Robert Blum, Patrick Lüningschrör, Thomas Andreska
Publikováno v:
The Journal of Neuroscience
Motor learning depends on synaptic plasticity between corticostriatal projections and striatal medium spiny neurons. Retrograde tracing from the dorsolateral striatum reveals that both layer II/III and V neurons in the motor cortex express BDNF as a
Autor:
Bai Lu, Nicoletta Berardi, Beatrice Vignoli, Valerio Bonaldo, Gabriele Sansevero, Robert Blum, Spartaco Santi, Manju Sasi, Marco Canossa, Emiliano Biasini, Roberto Rimondini
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-17 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-17 (2021)
Memory consolidation requires astrocytic microdomains for protein recycling; but whether this lays a mechanistic foundation for long-term information storage remains enigmatic. Here we demonstrate that persistent synaptic strengthening invited astroc
Autor:
Marco Canossa, Nicoletta Berardi, Spartaco Santi, Manju Sasi, Roberto Rimondini-Giorgini, Robert Blum, Bai Lu, Gabriele Sansevero, Beatrice Vignoli
Publikováno v:
Research Square
Memory consolidation requires astrocytic microdomains for protein recycling; but whether this lays a mechanistic foundation for long-term information storage remains enigmatic. Here we demonstrate that persistent synaptic strengthening invited astroc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3e9cdd3c41c28bb7e1caeacfde5fc09
https://doi.org/10.21203/rs.3.rs-139639/v1
https://doi.org/10.21203/rs.3.rs-139639/v1
Autor:
Christopher M. Klinke, Matthias Lange, Manju Sasi, Hans-Christian Pape, Dominik Fiedler, Marta Andreatta, Robert Blum
Publikováno v:
J Neurosci
Dysregulation of proteins involved in synaptic plasticity is associated with pathologies in the CNS, including psychiatric disorders. The bed nucleus of the stria terminalis (BNST), a brain region of the extended amygdala circuit, has been identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a04853f05b9d1b87008417a68bdc7de7
https://europepmc.org/articles/PMC7821854/
https://europepmc.org/articles/PMC7821854/
Autor:
Anupam Sah, Dennis Segebarth, Nikolai Stein, Christoph M. Flath, Robert Blum, Hans-Christian Pape, Christina Lillesaar, Maren D. Lange, Dominik Fiedler, Ramon O. Tasan, Matthias Griebel, Teresa M. Lüffe, Corinna Martin, Nicolas Singewald, Rohini Gupta, Lucas B. Comeras, Manju Sasi, Cora R. von Collenberg, Alexander Dürr, Victoria Schoeffler
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d2b5b1eb1d68795e3e41dae52a2399c
https://doi.org/10.7554/elife.59780.sa2
https://doi.org/10.7554/elife.59780.sa2
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 3, p e1006054 (2018)
PLoS Computational Biology
PLoS Computational Biology
Local and spontaneous calcium signals play important roles in neurons and neuronal networks. Spontaneous or cell-autonomous calcium signals may be difficult to assess because they appear in an unpredictable spatiotemporal pattern and in very small ne
Autor:
Thomas M. Frimurer, Daniel Gilbert, Dieter Janzen, Carmen Villmann, Manju Sasi, Sinem Milanos, Katharina Kuenzel, Andrea Buettner
Publikováno v:
Biological chemistryReferences. 399(6)
GABAA receptors are ligand-gated anion channels that form pentameric arrangements of various subunits. Positive allosteric modulators of GABAA receptors have been reported as being isolated either from plants or synthesized analogs of known GABAA rec