Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Manja Wachsmuth"'
Publikováno v:
PLoS Genetics, Vol 12, Iss 3, p e1005939 (2016)
The mitochondrial (mt) genome is present in many copies in human cells, and intra-individual variation in mtDNA sequences is known as heteroplasmy. Recent studies found that heteroplasmies are highly tissue-specific, site-specific, and allele-specifi
Externí odkaz:
https://doaj.org/article/97b3ab326e63462985c2dc0ae7ae5437
Publikováno v:
Umweltinformationssysteme-Wie trägt die Digitalisierung zur Nachhaltigkeit bei? ISBN: 9783658356842
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74885bd13d43feffc39f610c18ee4e97
https://doi.org/10.1007/978-3-658-35685-9_3
https://doi.org/10.1007/978-3-658-35685-9_3
Autor:
Manja Wachsmuth, Gerlinde Knetsch
Publikováno v:
Umweltinformationssysteme – Wie verändert die Digitalisierung unsere Gesellschaft? ISBN: 9783658308889
Aktuelle, umfassende und verlassliche Informationen uber umweltrelevante Eigenschaften von chemischen Stoffen sind fur alle Bereiche des Umweltschutzes und zur Gefahrenabwehr von groser Bedeutung. Um solche Informationen einheitlich verfugbar zu mach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce86c3cd64969097953a9358c68d2327
https://doi.org/10.1007/978-3-658-30889-6_14
https://doi.org/10.1007/978-3-658-30889-6_14
Autor:
Roland Schroeder, Manja Wachsmuth, Mark Stoneking, Mingkun Li, Burkhard Madea, Alexander Huebner, Anna Maria Eis-Huebinger
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
Mitochondrial DNA (mtDNA) heteroplasmy (intra-individual variation) varies among different human tissues and increases with age, suggesting that the majority of mtDNA heteroplasmies are acquired, rather than inherited. However, the extent to which he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e6803de7c05e984ec0b56b28497647
Publikováno v:
Nucleic Acids Research
Riboswitches are regulatory RNA elements typically located in the 50-untranslated region of certain mRNAs and control gene expression at the level of transcription or translation. These elements consist of a sensor and an adjacent actuator domain. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08af60071554d5c21c42ccc8d9b9d54b
https://doi.org/10.1093/nar/gks1330
https://doi.org/10.1093/nar/gks1330
Autor:
Gesine, Domin, Sven, Findeiß, Manja, Wachsmuth, Sebastian, Will, Peter F, Stadler, Mario, Mörl
Publikováno v:
Nucleic Acids Research
Riboswitches have gained attention as tools for synthetic biology, since they enable researchers to reprogram cells to sense and respond to exogenous molecules. In vitro evolutionary approaches produced numerous RNA aptamers that bind such small liga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3f1fcedc0adf38fb1e1db28defa0bde7
https://pubmed.ncbi.nlm.nih.gov/27994029
https://pubmed.ncbi.nlm.nih.gov/27994029
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 12, Iss 3, p e1005939 (2016)
PLoS Genetics, Vol 12, Iss 3, p e1005939 (2016)
The mitochondrial (mt) genome is present in many copies in human cells, and intra-individual variation in mtDNA sequences is known as heteroplasmy. Recent studies found that heteroplasmies are highly tissue-specific, site-specific, and allele-specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8692deeb43ecf4ad1e3932dcff194da
https://pubmed.ncbi.nlm.nih.gov/26978189
https://pubmed.ncbi.nlm.nih.gov/26978189
Publikováno v:
Methods in enzymology. 550
In this chapter, we review both computational and experimental aspects of de novo RNA sequence design. We give an overview of currently available design software and their limitations, and discuss the necessary setup to experimentally validate proper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::caf825f0ea549729a768ae5f8bcbeb14
https://pubmed.ncbi.nlm.nih.gov/25605378
https://pubmed.ncbi.nlm.nih.gov/25605378
In this chapter, we review both computational and experimental aspects of de novo RNA sequence design. We give an overview of currently available design software and their limitations, and discuss the necessary setup to experimentally validate proper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50b031addf091f614f461f9654d57026
https://doi.org/10.1016/bs.mie.2014.10.029
https://doi.org/10.1016/bs.mie.2014.10.029
Autor:
Ronny Lorenz, Sven Findeiß, Peter F. Stadler, Gesine Domin, Mario Mörl, Robert Serfling, Manja Wachsmuth
Riboswitches are RNA-based regulators of gene expression composed of a ligand-sensing aptamer domain followed by an overlapping expression platform. The regulation occurs at either the level of transcription (by formation of terminator or antitermina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3278e40701d28c9c72c5553c8f313601
https://publica.fraunhofer.de/handle/publica/239874
https://publica.fraunhofer.de/handle/publica/239874