Interaction of polysialic acid with CCL21 regulates the migratory capacity of human dendritic cells.

Autor: Marieke Bax, Sandra J van Vliet, Manja Litjens, Juan J García-Vallejo, Yvette van Kooyk

Publikováno v: PLoS ONE, Vol 4, Iss 9, p e6987 (2009)

Dendritic cells (DCs) are the most potent antigen-presenting cells (APCs). Immature DCs (iDCs) are situated in the periphery where they capture pathogen. Subsequently, they migrate as mature DCs (mDCs) to draining lymph nodes to activate T cells. CCR

Externí odkaz: https://doaj.org/article/8ae8b1238be94b65ba4e4ba2d2e362a1

Salp15 binding to DC-SIGN inhibits cytokine expression by impairing both nucleosome remodeling and mRNA stabilization.

Autor: Joppe W R Hovius, Marein A W P de Jong, Jeroen den Dunnen, Manja Litjens, Erol Fikrig, Tom van der Poll, Sonja I Gringhuis, Teunis B H Geijtenbeek

Publikováno v: PLoS Pathogens, Vol 4, Iss 2, p e31 (2008)

Ixodes ticks are major vectors for human pathogens, such as Borrelia burgdorferi, the causative agent of Lyme disease. Tick saliva contains immunosuppressive molecules that facilitate tick feeding and B. burgdorferi infection. We here demonstrate, to

Externí odkaz: https://doaj.org/article/fc03abd8a9664cb38d2c90db72a5cb93

The association between antibodies to neurotropic pathogens and bipolar disorder : A study in the Dutch Bipolar (DB) Cohort and meta-analysis

Autor: Marieke J. H. Begemann, Hans C. van Mierlo, Manja Litjens, René S. Kahn, Lot de Witte, Marco P. Boks, Arjen L. Sutterland, Roel A. Ophoff, G. Snijders

Publikováno v: Translational psychiatry, vol 9, iss 1
Translational psychiatry, 9(1):311. Nature Publishing Group
Translational Psychiatry, 9(1). Nature Publishing Group

Exposure to neurotropic pathogens has been hypothesized to be a risk factor for the development of bipolar disorder (BD). However, evidence so far is inconsistent. We, therefore, analyzed the seroprevalence and titer levels of IgG antibodies against

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad568bfb38abbbf708ef6e2f4da03c2f
https://hdl.handle.net/1874/391724

No association between anti-thyroidperoxidase antibodies and bipolar disorder: a study in the Dutch Bipolar Cohort and a meta-analysis

Autor: L.D. de Witte, C. van der Laan, R.S. Kahn, G. Snijders, Manja Litjens, D. van den Berk, M. H. J. Hillegers, E. Regeer, A. Berdenis van Berlekom, Roel A. Ophoff, Marco P. Boks, Marieke J. H. Begemann

Publikováno v: Psychoneuroendocrinology, 112:Unsp 104518. Elsevier Ltd.

Background Thyroid autoimmunity has been associated with bipolar disorder (BD). However, results from previous studies on the seroprevalence of anti-thyroid peroxidase antibodies (TPO-abs) in BD are inconsistent. Objectives The aim of the present stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54133facec599d2d23de1f4946f44f2f
https://pubmed.ncbi.nlm.nih.gov/31780186

Are infectious agents involved in the pathogenesis of postpartum psychosis?

Autor: Steven A. Kushner, Lot de Witte, Veerle Bergink, Astrid M. Kamperman, G. Snijders, René S. Kahn, Manja Litjens

Publikováno v: Journal of Affective Disorders, 229, 141-144. Elsevier
Journal of Affective Disorders, 229, 141. Elsevier

Background Since postpartum psychosis has been linked to activation of the immune system, it has been hypothesized that infectious agents may be involved in the pathogenesis of this disorder. We therefore investigated whether exposure to pathogens th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aa2320ae182dd4fe3232e6dedf72893
https://pubmed.ncbi.nlm.nih.gov/29310062