Therapeutic antibody activation of the glucocorticoid-induced TNF receptor by a clustering mechanism.

Autor: He C; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY, USA., Maniyar RR; Ludwig Collaborative and Swim Across America Laboratory, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Avraham Y; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel., Zappasodi R; Ludwig Collaborative and Swim Across America Laboratory, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Parker Institute for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell Medicine, New York, NY, USA.; Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, New York, NY, USA., Rusinova R; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY, USA., Newman W; Leap Therapeutics, Cambridge, MA, USA., Heath H; Leap Therapeutics, Cambridge, MA, USA., Wolchok JD; Ludwig Collaborative and Swim Across America Laboratory, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Parker Institute for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell Medicine, New York, NY, USA.; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Dahan R; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel., Merghoub T; Ludwig Collaborative and Swim Across America Laboratory, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Parker Institute for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell Medicine, New York, NY, USA.; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Meyerson JR; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY, USA.

Publikováno v: Science advances [Sci Adv] 2022 Feb 25; Vol. 8 (8), pp. eabm4552. Date of Electronic Publication: 2022 Feb 25.

Interacting Genetic Lesions of Melanoma in the Tumor Microenvironment: Defining a Viable Therapy.

Autor: Maniyar RR; Human Oncology and Pathogenesis Program, Ludwig Collaborative and Swim Across America Laboratory, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Chakraborty S; Department of Medicine, Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, NY, USA., Jarboe T; Departments of Pathology, Microbiology and Immunology, New York Medical College, Valhalla, NY, USA., Suriano R; Division of Natural Sciences, College of Mount Saint Vincent, Bronx, NY, USA., Wallack M; Department Surgery, Metropolitan Hospital, New York, NY, USA., Geliebter J; Departments of Pathology, Microbiology and Immunology, New York Medical College, Valhalla, NY, USA., Tiwari RK; Departments of Pathology, Microbiology and Immunology, New York Medical College, Valhalla, NY, USA. Raj_Tiwari@nymc.edu.

Publikováno v: Advances in experimental medicine and biology [Adv Exp Med Biol] 2021; Vol. 1350, pp. 123-143.