Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Manita, Shakya"'
Autor:
Manita Shakya, Karen P. Briski
Publikováno v:
Endocrinology and Metabolism, Vol 32, Iss 4, Pp 475-484 (2017)
BackgroundShort-term interruption of feeding is ordinary in modern life but negatively impacts appetite control and body weight. Estradiol (E) imposes long-term inhibitory tonus on food consumption; however, E influence on energy repletion secondary
Externí odkaz:
https://doaj.org/article/789a7a3938074eeb8274b68278daafd7
Publikováno v:
Cell Stress & Chaperones
Cell Stress Chaperones
Cell Stress Chaperones
The secretory pathway of neurons and endocrine cells contains a variety of mechanisms designed to combat cellular stress. These include not only the unfolded protein response pathways but also diverse chaperone proteins that collectively work to ensu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82fc9a759b678e2bd22c8c4afb25c40b
http://europepmc.org/articles/PMC7591655
http://europepmc.org/articles/PMC7591655
Autor:
Manita Shakya, Surbhi Gahlot, Nicolle K Martin, Anoop Arunagiri, Martin G Martin, Peter Arvan, Malcolm J Low, Iris Lindberg
Publikováno v:
Endocrinology
PCSK1 encodes an enzyme required for prohormone maturation into bioactive peptides. A striking number of single nucleotide polymorphisms and rare mutations in PCSK1 are associated with a range of clinical phenotypes. Infants bearing 2 copies of a cat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f5ddcfaf87e1c8001abf122f02f362c
https://doi.org/10.1210/endocr/bqac024
https://doi.org/10.1210/endocr/bqac024
Autor:
Prabhat R, Napit, Md Haider, Ali, Manita, Shakya, Santosh K, Mandal, Khaggeswar, Bheemanapally, A S M Hasan, Mahmood, Mostafa M H, Ibrahim, K P, Briski
Publikováno v:
Neuroscience
Neural substrates for estrogen regulation of glucose homeostasis remain unclear. Female rat dorsal vagal complex (DVC) A2 noradrenergic neurons are estrogen- and metabolic-sensitive. The ventromedial hypothalamic nucleus (VMN) is a key component of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56ab67c45c94f6405a6e54e669373c38
https://doi.org/10.1016/j.neuroscience.2019.05.007
https://doi.org/10.1016/j.neuroscience.2019.05.007
Publikováno v:
Endocrinology
Pro-opiomelanocortin (POMC) neurons form an integral part of the central melanocortin system regulating food intake and energy expenditure. Genetic and pharmacological studies have revealed that defects in POMC synthesis, processing, and receptor sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96bc7ec496784e6bf5be59595625b504
https://doi.org/10.1210/endocr/bqab055
https://doi.org/10.1210/endocr/bqab055
Autor:
Iris Lindberg, Manita Shakya
Publikováno v:
Endocr Rev
The kexin-like proprotein convertases perform the initial proteolytic cleavages that ultimately generate a variety of different mature peptide and proteins, ranging from brain neuropeptides to endocrine peptide hormones, to structural proteins, among
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e5569c855498eb2084d38125b630ea5
https://pubmed.ncbi.nlm.nih.gov/33382413
https://pubmed.ncbi.nlm.nih.gov/33382413
Autor:
Malcolm J. Low, Anis Hassan, Manita Shakya, Surbhi Gahlot, Peter Arvan, Iris Lindberg, Anoop Arunagiri
Publikováno v:
Journal of the Endocrine Society
A striking number of SNPs and rare mutations have been identified in PCSK1, the gene that codes for the enzyme proprotein convertase 1/3 (PC1/3) which proteolytically activates prohormones within the secretory pathway. All infants bearing two copies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a336ad66b46b1eba65e5555e2fd9a4b
http://europepmc.org/articles/PMC7208903
http://europepmc.org/articles/PMC7208903
Autor:
Prem K. Shrestha, Fahaad S.H. Alenazi, Santosh K. Mandal, Manita Shakya, Hussain N. Alhamami, Karen P. Briski
Publikováno v:
Neuropeptides. 70:37-46
Background Caudal dorsomedial hindbrain detection of hypoglycemia-associated lactoprivation regulates glucose counter-regulation in male rats. In females, estradiol (E) determines hypothalamic neuroanatomical and molecular foci of hindbrain energy se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010b4309cffec4ae1117355a0aedb1b3
https://doi.org/10.1016/j.npep.2018.05.004
https://doi.org/10.1016/j.npep.2018.05.004
Autor:
Timothy S Jarvela, Surbhi Gahlot, Manita Shakya, Tomas Bachor, Anne White, Malcolm J Low, Iris Lindberg
Publikováno v:
Endocrinology
Common mutations in the human prohormone convertase 1/3 (PC1/3) gene (PCSK1) are linked to increased risk of obesity. Previous work has shown that the rs6232 SNP (N221D) results in slightly decreased activity, though whether this decrease underlies o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2249362ea67e85d56e01d1a5cb3d7843
https://doi.org/10.1210/en.2019-00418
https://doi.org/10.1210/en.2019-00418
Publikováno v:
Cell Stress and Chaperones. 25:943-943
Due to an unfortunate mistake during the production process, the last sentence of the second last paragraph of the Discussion section contains an error as the words ‘increases’ and ‘decreased’ were transposed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53202297cb6e6f9b4b5bb3bc1278e1c0
https://doi.org/10.1007/s12192-020-01138-5
https://doi.org/10.1007/s12192-020-01138-5