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pro vyhledávání: '"Manishita Rani"'
Autor:
Bhavna Saroha, Gourav Kumar, Suresh Kumar, Meena Kumari, Manishita Rani, Neera Raghav, Pranab Kumar Sahoo, Sushmita Ghosh, Sutapa Mahata, Vilas D. Nasare
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 5, Iss , Pp 100056- (2022)
In the present study, we have designed a series of novel 1,2,3-triazole-aurone hybrids, which were synthesized by a one-pot click reaction between a terminal alkyne and an in-situ generated azide, and evaluated as potential cathepsin B inhibitors. Th
Externí odkaz:
https://doaj.org/article/57e7e7f4dc694399828bc1e66d6b20cd
Autor:
Bhavna Saroha, Gourav Kumar, Suresh Kumar, Meena Kumari, Manishita Rani, Neera Raghav, Pranab Kumar Sahoo, Sushmita Ghosh, Sutapa Mahata, Vilas D. Nasare
Publikováno v:
Current Research in Green and Sustainable Chemistry, Vol 5, Iss , Pp 100295- (2022)
Cathepsin B represents a group of lysosomal-encapsulated cellular cysteine proteases, whose upregulation is the critical risk factor for cancer progression and in the regulation of degenerative processes like apoptosis. Therefore, cysteine cathepsins
Externí odkaz:
https://doaj.org/article/3023cb4c38b645eeb629842a4e3bb768