Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Manisha Priyadarsini Sahoo"'
Autor:
Indrajit Sahu, Sachitanand M. Mali, Prasad Sulkshane, Cong Xu, Andrey Rozenberg, Roni Morag, Manisha Priyadarsini Sahoo, Sumeet K. Singh, Zhanyu Ding, Yifan Wang, Sharleen Day, Yao Cong, Oded Kleifeld, Ashraf Brik, Michael H. Glickman
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
The 20S particle is part of the 26S proteasome, but also exists as a free complex. Here, the authors outline signature activities of the 20S and combine chemical, structural, functional and proteomic assays to show that the 20S can degrade ubiquitin
Externí odkaz:
https://doaj.org/article/46cc92bf4c3f4fcfb5bb5b4fa465398a
Proteasomes are multi-subunit, multi-catalytic protein complexes present in eukaryotic cells that degrade misfolded, damaged, or unstructured proteins. In this study, we used an activity-guided proteomic methodology based on fluorogenic peptide subst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f79f081ee19814eb7350d4bf4c6ecdc
https://doi.org/10.1101/2023.03.30.534963
https://doi.org/10.1101/2023.03.30.534963
Publikováno v:
The Ubiquitin Code ISBN: 9781071628584
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed97c42f8ae0625d00769d5a172dcaca
https://doi.org/10.1007/978-1-0716-2859-1_17
https://doi.org/10.1007/978-1-0716-2859-1_17
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2602
Analyzing intracellular peptides generated by proteasomes is highly informative to understand the spatiotemporal regulation of protein homeostasis. A large portion of eukaryotic proteins is proteolyzed within the 20S core particle of the 26S holoenzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::14710ded2d76274751de118c67fbc4e4
https://pubmed.ncbi.nlm.nih.gov/36446979
https://pubmed.ncbi.nlm.nih.gov/36446979
Autor:
Cong Xu, Indrajit Sahu, Andrey Rozenberg, Roni Morag, Sumeet K. Singh, Yao Cong, Manisha Priyadarsini Sahoo, Sachitanand M. Mali, Michael H. Glickman, Zhanyu Ding, Sharleen Day, Prasad Sulkshane, Ashraf Brik, Oded Kleifeld, Yifan Wang
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
The proteasome, the primary protease for ubiquitin-dependent proteolysis in eukaryotes, is usually found as a mixture of 30S, 26S, and 20S complexes. These complexes have common catalytic sites, which makes it challenging to determine their distincti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d4b8d1326c3cace48f1bd38a2e9fa4
Autor:
Zhanyu Ding, Cong Xu, Indrajit Sahu, Sumeet K. Singh, Andrey Rozenberg, Manisha Priyadarsini Sahoo, Yifan Wang, Prasad Sulkshane, Sachitanand M. Mali, Roni Morag, Yao Cong, Michael H. Glickman, Sharleen Day, Ashraf Brik, Oded Kleifeld
Publikováno v:
BioRxIV
bioRxiv
bioRxiv
Careful removal of unwanted proteins is necessary for cell survival. The primary constitutive intracellular protease is the 26S proteasome complex, often found in equilibrium with its free catalytic subcomplex– the 20S core particle. Protein degrad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c28de01de89fa73cc779b4f8d1e812a