Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Manisha Kusch-Poddar"'
Autor:
Ulrich Schmitt, Manisha Kusch-Poddar, Heike Gutmann, Christoph Hiemke, Katrin M. Kirschbaum, Jürgen Drewe, Birk Poller
Publikováno v:
Pharmacology Biochemistry and Behavior. 102:312-320
Background P-glycoprotein (P-gp), an efflux transporter of the blood–brain barrier, limits the access of multiple xenobiotics to the central nervous system (CNS). Thus drug-dependent inhibition, induction or genetic variation of P-gp impacts drug t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::655ce8c96e0930c01fc76809e64aed62
https://doi.org/10.1016/j.pbb.2012.04.002
https://doi.org/10.1016/j.pbb.2012.04.002
Publikováno v:
Brain research. 1064(1-2)
In vitro models of the blood-brain barrier (BBB) play a major role in the study of BBB permeability of drug candidates. However, most established in vitro models use cells of non-human origin, which is not optimal for the prediction of brain permeabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::872925ce4272280d582bf498f2fbc43e
https://pubmed.ncbi.nlm.nih.gov/16289483
https://pubmed.ncbi.nlm.nih.gov/16289483